PDB: 7A4O — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7A4OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7A4OA Q13627 136 481 763.0 ANP:501 ATPlike Active DFGin 7.4043 15.0335 BLAminus -121.6, 173.77 67.88, 73.96 -92.34, 22.26 284.87, 82.1 -70.26, -21.97 in-in in 8.6845 Saltbr-in 2.7935 HRD-in -65.03, -49.19 79.83, -0.94 in-in-in SNCiii in-in ActLoopNT-in 2.7995 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.61, 174.39 APE9-dihe-na 70.74, 151.67 APE8-dihe-in -72.34, 134.57 APE8-rot-in 295.77 APE67-dihe-in -65.19, -24.46 -43.45, -47.13 APE12-dist-in 10.0985 APE11-dist-in 12.2369 APE10-dist-in 7.723 APE9-dist-in 3.1562 None PTR321 PTR321 XRAY 1.9 0.18 0.203 A 382.0 341.0 5 25 25 0 [[159, 479]] 1.0 7a4o CMGC_DYRK1A_HUMAN CMGC 1e-90 310.0 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7A4OB Q13627 134 481 763.0 ANP:501 ATPlike Inactive DFGin 7.2232 15.0468 BLAminus -127.4, 170.29 72.8, 80.08 -93.18, 24.5 286.73, 76.67 -71.46, -26.03 in-in in 8.3652 Saltbr-in 2.7974 HRD-in -57.9, -49.71 71.19, 2.83 in-in-out SNCiio in-out ActLoopNT-in 2.8396 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -84.65, 164.16 APE9-dihe-na 75.07, 150.77 APE8-dihe-in -68.35, 138.34 APE8-rot-in 298.16 APE67-dihe-in -63.89, -24.74 -46.52, -48.39 APE12-dist-out 14.0969 APE11-dist-in 11.8963 APE10-dist-in 7.5367 APE9-dist-in 3.0281 None PTR321 PTR321 XRAY 1.9 0.18 0.203 B 382.0 341.0 7 25 25 0 [[159, 479]] 1.0 7a4o CMGC_DYRK1A_HUMAN CMGC 1e-90 310.0 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 7A4O — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7A4OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7A4OA Q13627 136 481 763.0 ANP:501 ATPlike Active DFGin 7.4043 15.0335 BLAminus -121.6, 173.77 67.88, 73.96 -92.34, 22.26 284.87, 82.1 -70.26, -21.97 in-in in 8.6845 Saltbr-in 2.7935 HRD-in -65.03, -49.19 79.83, -0.94 in-in-in SNCiii in-in ActLoopNT-in 2.7995 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.61, 174.39 APE9-dihe-na 70.74, 151.67 APE8-dihe-in -72.34, 134.57 APE8-rot-in 295.77 APE67-dihe-in -65.19, -24.46 -43.45, -47.13 APE12-dist-in 10.0985 APE11-dist-in 12.2369 APE10-dist-in 7.723 APE9-dist-in 3.1562 None PTR321 PTR321 XRAY 1.9 0.18 0.203 A 382.0 341.0 5 25 25 0 [[159, 479]] 1.0 7a4o Homo sapiens CMGC_DYRK1A_HUMAN CMGC 1e-90 310.0 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7A4OB Q13627 134 481 763.0 ANP:501 ATPlike Inactive DFGin 7.2232 15.0468 BLAminus -127.4, 170.29 72.8, 80.08 -93.18, 24.5 286.73, 76.67 -71.46, -26.03 in-in in 8.3652 Saltbr-in 2.7974 HRD-in -57.9, -49.71 71.19, 2.83 in-in-out SNCiio in-out ActLoopNT-in 2.8396 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -84.65, 164.16 APE9-dihe-na 75.07, 150.77 APE8-dihe-in -68.35, 138.34 APE8-rot-in 298.16 APE67-dihe-in -63.89, -24.74 -46.52, -48.39 APE12-dist-out 14.0969 APE11-dist-in 11.8963 APE10-dist-in 7.5367 APE9-dist-in 3.0281 None PTR321 PTR321 XRAY 1.9 0.18 0.203 B 382.0 341.0 7 25 25 0 [[159, 479]] 1.0 7a4o Homo sapiens CMGC_DYRK1A_HUMAN CMGC 1e-90 310.0 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 7A4O — CMGC DYR1A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name