PDB: 6QU2 — CMGC DYR1A_HUMAN

Total number of chains: 4
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6QU2A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 6QU2A Q13627 134 482 763.0 JHW:506 Type1 Active DFGin 6.982 14.589 BLAminus -117.63, 177.32 58.78, 78.21 -94.48, 27.81 290.76, 75.74 -69.1, -16.2 in-in in 8.568 Saltbr-in 2.854 HRD-in -61.74, -43.97 72.49, -0.84 in-in-in SNCiii in-in ActLoopNT-in 2.807 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.02, 172.07 APE9-dihe-na 71.62, 149.26 APE8-dihe-in -69.7, 147.81 APE8-rot-in 285.05 APE67-dihe-in -59.57, -29.32 -59.04, -45.45 APE12-dist-in 12.878 APE11-dist-in 11.444 APE10-dist-in 7.011 APE9-dist-in 3.089 None PTR321 PTR321 XRAY 2.9 0.204 0.242 A 361 349 0 0 0 0 [[159, 479]] 1.0 6qu2 CMGC_DYRK1A_HUMAN CMGC 8.4e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6QU2B Q13627 134 482 763.0 JHW:508 Type1 Active DFGin 7.005 14.638 BLAminus -117.89, 176.82 58.51, 78.25 -94.64, 27.55 290.8, 75.81 -68.12, -17.63 in-in in 8.561 Saltbr-in 2.852 HRD-in -61.86, -43.77 71.78, 1.07 in-in-in SNCiii in-in ActLoopNT-in 2.812 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.33, 172.98 APE9-dihe-na 71.69, 147.87 APE8-dihe-in -69.83, 147.77 APE8-rot-in 285.59 APE67-dihe-in -59.33, -29.5 -59.31, -45.22 APE12-dist-in 12.876 APE11-dist-in 11.482 APE10-dist-in 7.021 APE9-dist-in 3.097 None PTR321 PTR321 XRAY 2.9 0.204 0.242 B 361 349 0 0 0 0 [[159, 479]] 1.0 6qu2 CMGC_DYRK1A_HUMAN CMGC 8.4e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6QU2C Q13627 134 482 763.0 JHW:505 Type1 Active DFGin 7.004 14.655 BLAminus -118.42, 176.92 59.0, 78.18 -94.14, 27.62 291.21, 74.99 -69.86, -15.95 in-in in 8.578 Saltbr-in 2.854 HRD-in -61.48, -44.17 72.54, -0.44 in-in-in SNCiii in-in ActLoopNT-in 2.8 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.57, 172.15 APE9-dihe-na 71.25, 147.44 APE8-dihe-in -70.36, 148.07 APE8-rot-in 286.47 APE67-dihe-in -59.29, -29.31 -59.04, -45.15 APE12-dist-in 12.889 APE11-dist-in 11.507 APE10-dist-in 7.035 APE9-dist-in 3.102 None PTR321 PTR321 XRAY 2.9 0.204 0.242 C 361 349 0 0 0 0 [[159, 479]] 1.0 6qu2 CMGC_DYRK1A_HUMAN CMGC 8.4e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6QU2D Q13627 134 482 763.0 JHW:504 Type1 Active DFGin 6.989 14.664 BLAminus -118.28, 176.89 59.45, 77.75 -95.14, 28.05 290.79, 75.43 -69.23, -15.75 in-in in 8.547 Saltbr-in 2.858 HRD-in -61.16, -43.94 72.27, -0.05 in-in-in SNCiii in-in ActLoopNT-in 2.802 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.09, 173.93 APE9-dihe-na 71.93, 148.3 APE8-dihe-in -68.69, 147.47 APE8-rot-in 287.5 APE67-dihe-in -59.03, -30.52 -59.66, -44.67 APE12-dist-in 13.01 APE11-dist-in 11.567 APE10-dist-in 7.068 APE9-dist-in 3.083 None PTR321 PTR321 XRAY 2.9 0.204 0.242 D 361 349 0 0 0 0 [[159, 479]] 1.0 6qu2 CMGC_DYRK1A_HUMAN CMGC 8.4e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 6QU2 — CMGC DYR1A_HUMAN

Total number of chains: 4
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6QU2A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 6QU2A Q13627 134 482 763.0 JHW:506 Type1 Active DFGin 6.982 14.589 BLAminus -117.63, 177.32 58.78, 78.21 -94.48, 27.81 290.76, 75.74 -69.1, -16.2 in-in in 8.568 Saltbr-in 2.854 HRD-in -61.74, -43.97 72.49, -0.84 in-in-in SNCiii in-in ActLoopNT-in 2.807 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.02, 172.07 APE9-dihe-na 71.62, 149.26 APE8-dihe-in -69.7, 147.81 APE8-rot-in 285.05 APE67-dihe-in -59.57, -29.32 -59.04, -45.45 APE12-dist-in 12.878 APE11-dist-in 11.444 APE10-dist-in 7.011 APE9-dist-in 3.089 None PTR321 PTR321 XRAY 2.9 0.204 0.242 A 361 349 0 0 0 0 [[159, 479]] 1.0 6qu2 Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.4e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6QU2B Q13627 134 482 763.0 JHW:508 Type1 Active DFGin 7.005 14.638 BLAminus -117.89, 176.82 58.51, 78.25 -94.64, 27.55 290.8, 75.81 -68.12, -17.63 in-in in 8.561 Saltbr-in 2.852 HRD-in -61.86, -43.77 71.78, 1.07 in-in-in SNCiii in-in ActLoopNT-in 2.812 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.33, 172.98 APE9-dihe-na 71.69, 147.87 APE8-dihe-in -69.83, 147.77 APE8-rot-in 285.59 APE67-dihe-in -59.33, -29.5 -59.31, -45.22 APE12-dist-in 12.876 APE11-dist-in 11.482 APE10-dist-in 7.021 APE9-dist-in 3.097 None PTR321 PTR321 XRAY 2.9 0.204 0.242 B 361 349 0 0 0 0 [[159, 479]] 1.0 6qu2 Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.4e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6QU2C Q13627 134 482 763.0 JHW:505 Type1 Active DFGin 7.004 14.655 BLAminus -118.42, 176.92 59.0, 78.18 -94.14, 27.62 291.21, 74.99 -69.86, -15.95 in-in in 8.578 Saltbr-in 2.854 HRD-in -61.48, -44.17 72.54, -0.44 in-in-in SNCiii in-in ActLoopNT-in 2.8 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.57, 172.15 APE9-dihe-na 71.25, 147.44 APE8-dihe-in -70.36, 148.07 APE8-rot-in 286.47 APE67-dihe-in -59.29, -29.31 -59.04, -45.15 APE12-dist-in 12.889 APE11-dist-in 11.507 APE10-dist-in 7.035 APE9-dist-in 3.102 None PTR321 PTR321 XRAY 2.9 0.204 0.242 C 361 349 0 0 0 0 [[159, 479]] 1.0 6qu2 Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.4e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6QU2D Q13627 134 482 763.0 JHW:504 Type1 Active DFGin 6.989 14.664 BLAminus -118.28, 176.89 59.45, 77.75 -95.14, 28.05 290.79, 75.43 -69.23, -15.75 in-in in 8.547 Saltbr-in 2.858 HRD-in -61.16, -43.94 72.27, -0.05 in-in-in SNCiii in-in ActLoopNT-in 2.802 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.09, 173.93 APE9-dihe-na 71.93, 148.3 APE8-dihe-in -68.69, 147.47 APE8-rot-in 287.5 APE67-dihe-in -59.03, -30.52 -59.66, -44.67 APE12-dist-in 13.01 APE11-dist-in 11.567 APE10-dist-in 7.068 APE9-dist-in 3.083 None PTR321 PTR321 XRAY 2.9 0.204 0.242 D 361 349 0 0 0 0 [[159, 479]] 1.0 6qu2 Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.4e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 6QU2 — CMGC DYR1A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name