PDB: 6EIV — CMGC DYR1A_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6EIVA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 6EIVA Q13627 134 480 763.0 B6Q:501 Type1 Inactive DFGin 7.555 15.152 BLAminus -120.84, 171.67 57.39, 86.98 -102.78, 35.14 274.84, 85.24 -78.55, -29.99 in-in in 8.863 Saltbr-in 2.667 HRD-in -64.41, -32.42 61.66, 3.26 in-in-out SNCiio in-out ActLoopNT-in 2.583 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -115.94, 171.35 APE9-dihe-na 64.29, 157.62 APE8-dihe-in -72.84, 149.54 APE8-rot-in 294.84 APE67-dihe-in -70.56, -22.33 -58.23, -37.84 APE12-dist-in 13.979 APE11-dist-in 11.914 APE10-dist-out 8.132 APE9-dist-in 3.157 None PTR321 PTR321 XRAY 2.68 0.2 0.235 A 368 342 5 0 0 0 [[159, 479]] 1.0 6eiv CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6EIVB Q13627 133 480 763.0 B6Q:501 Type1 Inactive DFGin 7.838 15.054 BLAminus -117.46, 173.9 54.13, 86.38 -99.45, 36.06 278.29, 87.94 -79.83, -33.89 in-in in 9.001 Saltbr-in 2.687 HRD-in -72.2, -37.83 60.09, 15.76 in-in-out SNCiio in-out ActLoopNT-in 3.031 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -115.67, 152.23 APE9-dihe-na 68.73, 155.27 APE8-dihe-in -64.12, 146.96 APE8-rot-in 304.3 APE67-dihe-in -70.42, -38.71 -50.76, -42.3 APE12-dist-out 14.313 APE11-dist-in 11.293 APE10-dist-out 8.714 APE9-dist-in 3.185 None PTR321 PTR321 XRAY 2.68 0.2 0.235 B 368 340 8 0 0 0 [[159, 479]] 1.0 6eiv CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6EIVC Q13627 135 479 763.0 B6Q:501 Type1 Inactive DFGin 7.974 15.09 BLAminus -130.5, 162.34 68.37, 85.75 -108.43, 38.06 286.93, 86.81 -88.65, -21.51 in-in in 8.82 Saltbr-in 3.056 HRD-in -63.41, -36.37 61.31, 16.95 in-in-out SNCiio in-out ActLoopNT-in 3.132 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioi APE10-dihe-na -105.82, 169.53 APE9-dihe-na 68.49, 151.95 APE8-dihe-in -66.67, 153.42 APE8-rot-out 50.58 APE67-dihe-in -66.4, -29.21 -58.54, -50.01 APE12-dist-out 14.024 APE11-dist-in 12.006 APE10-dist-out 8.071 APE9-dist-in 3.196 None PTR321 PTR321 XRAY 2.68 0.2 0.235 C 368 333 12 0 0 0 [[159, 479]] 1.0 6eiv CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6EIVD Q13627 134 479 763.0 B6Q:501 Type1 Inactive DFGin 7.858 14.788 BLAminus -123.28, 170.55 60.69, 87.47 -104.63, 40.75 289.41, 79.15 -84.06, -24.98 in-in in 8.939 Saltbr-in 3.077 HRD-in -80.96, -33.53 58.1, 20.23 in-in-out SNCiio in-out ActLoopNT-in 2.757 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -123.8, 169.26 APE9-dihe-na 65.27, 152.41 APE8-dihe-in -65.12, 144.68 APE8-rot-in 294.25 APE67-dihe-in -62.96, -33.45 -60.21, -40.79 APE12-dist-in 13.884 APE11-dist-in 11.72 APE10-dist-out 8.139 APE9-dist-in 3.184 None PTR321 PTR321 XRAY 2.68 0.2 0.235 D 368 333 13 0 0 0 [[159, 479]] 1.0 6eiv CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 6EIV — CMGC DYR1A_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6EIVA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 6EIVA Q13627 134 480 763.0 B6Q:501 Type1 Inactive DFGin 7.555 15.152 BLAminus -120.84, 171.67 57.39, 86.98 -102.78, 35.14 274.84, 85.24 -78.55, -29.99 in-in in 8.863 Saltbr-in 2.667 HRD-in -64.41, -32.42 61.66, 3.26 in-in-out SNCiio in-out ActLoopNT-in 2.583 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -115.94, 171.35 APE9-dihe-na 64.29, 157.62 APE8-dihe-in -72.84, 149.54 APE8-rot-in 294.84 APE67-dihe-in -70.56, -22.33 -58.23, -37.84 APE12-dist-in 13.979 APE11-dist-in 11.914 APE10-dist-out 8.132 APE9-dist-in 3.157 None PTR321 PTR321 XRAY 2.68 0.2 0.235 A 368 342 5 0 0 0 [[159, 479]] 1.0 6eiv Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6EIVB Q13627 133 480 763.0 B6Q:501 Type1 Inactive DFGin 7.838 15.054 BLAminus -117.46, 173.9 54.13, 86.38 -99.45, 36.06 278.29, 87.94 -79.83, -33.89 in-in in 9.001 Saltbr-in 2.687 HRD-in -72.2, -37.83 60.09, 15.76 in-in-out SNCiio in-out ActLoopNT-in 3.031 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -115.67, 152.23 APE9-dihe-na 68.73, 155.27 APE8-dihe-in -64.12, 146.96 APE8-rot-in 304.3 APE67-dihe-in -70.42, -38.71 -50.76, -42.3 APE12-dist-out 14.313 APE11-dist-in 11.293 APE10-dist-out 8.714 APE9-dist-in 3.185 None PTR321 PTR321 XRAY 2.68 0.2 0.235 B 368 340 8 0 0 0 [[159, 479]] 1.0 6eiv Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6EIVC Q13627 135 479 763.0 B6Q:501 Type1 Inactive DFGin 7.974 15.09 BLAminus -130.5, 162.34 68.37, 85.75 -108.43, 38.06 286.93, 86.81 -88.65, -21.51 in-in in 8.82 Saltbr-in 3.056 HRD-in -63.41, -36.37 61.31, 16.95 in-in-out SNCiio in-out ActLoopNT-in 3.132 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioi APE10-dihe-na -105.82, 169.53 APE9-dihe-na 68.49, 151.95 APE8-dihe-in -66.67, 153.42 APE8-rot-out 50.58 APE67-dihe-in -66.4, -29.21 -58.54, -50.01 APE12-dist-out 14.024 APE11-dist-in 12.006 APE10-dist-out 8.071 APE9-dist-in 3.196 None PTR321 PTR321 XRAY 2.68 0.2 0.235 C 368 333 12 0 0 0 [[159, 479]] 1.0 6eiv Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6EIVD Q13627 134 479 763.0 B6Q:501 Type1 Inactive DFGin 7.858 14.788 BLAminus -123.28, 170.55 60.69, 87.47 -104.63, 40.75 289.41, 79.15 -84.06, -24.98 in-in in 8.939 Saltbr-in 3.077 HRD-in -80.96, -33.53 58.1, 20.23 in-in-out SNCiio in-out ActLoopNT-in 2.757 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -123.8, 169.26 APE9-dihe-na 65.27, 152.41 APE8-dihe-in -65.12, 144.68 APE8-rot-in 294.25 APE67-dihe-in -62.96, -33.45 -60.21, -40.79 APE12-dist-in 13.884 APE11-dist-in 11.72 APE10-dist-out 8.139 APE9-dist-in 3.184 None PTR321 PTR321 XRAY 2.68 0.2 0.235 D 368 333 13 0 0 0 [[159, 479]] 1.0 6eiv Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 6EIV — CMGC DYR1A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name