PDB: 6EIR — CMGC DYR1A_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6EIRA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 6EIRA Q13627 134 480 763.0 B6H:501 Type1 Inactive DFGin 7.393 14.795 BLAminus -125.18, 166.81 63.57, 86.84 -99.28, 31.63 287.87, 74.48 -70.6, -35.95 in-in in 8.782 Saltbr-in 2.895 HRD-in -63.53, -49.11 75.82, 12.8 in-in-out SNCiio in-out ActLoopNT-in 3.052 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -140.45, 163.14 APE9-dihe-na 68.93, 157.09 APE8-dihe-in -74.57, 134.52 APE8-rot-in 295.13 APE67-dihe-in -54.09, -35.75 -49.98, -47.46 APE12-dist-in 13.834 APE11-dist-in 11.859 APE10-dist-out 8.03 APE9-dist-in 3.209 None PTR321 PTR321 XRAY 2.4 0.235 0.258 A 368 342 5 0 0 0 [[159, 479]] 1.0 6eir CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6EIRB Q13627 133 480 763.0 B6H:501 Type1 Inactive DFGin 7.276 14.735 BLAminus -119.78, 174.81 68.91, 77.35 -98.17, 20.3 285.13, 87.39 -69.57, -27.99 in-in in 8.712 Saltbr-in 2.955 HRD-in -65.48, -40.64 68.84, 5.47 in-in-out SNCiio in-out ActLoopNT-in 2.731 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -144.55, 153.93 APE9-dihe-na 72.69, 153.36 APE8-dihe-in -69.83, 136.66 APE8-rot-in 293.84 APE67-dihe-in -59.39, -29.71 -51.99, -43.85 APE12-dist-out 14.548 APE11-dist-in 11.935 APE10-dist-out 8.485 APE9-dist-in 3.178 None PTR321 PTR321 XRAY 2.4 0.235 0.258 B 368 335 13 0 0 0 [[159, 479]] 1.0 6eir CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6EIRC Q13627 135 479 763.0 B6H:501 Type1 Inactive DFGin 7.412 15.039 BLAminus -130.82, 163.5 66.19, 85.94 -102.57, 28.49 281.77, 74.34 -75.43, -37.22 in-in in 8.512 Saltbr-in 2.752 HRD-in -65.03, -38.44 68.49, 5.65 in-in-out SNCiio in-out ActLoopNT-in 3.18 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -126.14, 166.06 APE9-dihe-na 64.03, 157.33 APE8-dihe-in -71.3, 146.96 APE8-rot-in 289.92 APE67-dihe-in -58.68, -32.01 -54.63, -47.82 APE12-dist-in 13.847 APE11-dist-in 11.909 APE10-dist-out 8.196 APE9-dist-in 3.124 None PTR321 PTR321 XRAY 2.4 0.235 0.258 C 368 333 12 0 0 0 [[159, 479]] 1.0 6eir CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6EIRD Q13627 134 479 763.0 B6H:501 Type1 Inactive DFGin 7.412 15.089 BLAminus -128.73, 160.15 68.25, 89.2 -103.65, 29.38 289.19, 75.86 -72.84, -26.68 in-in in 8.657 Saltbr-in 2.915 HRD-in -59.93, -46.06 73.72, 10.04 in-in-out SNCiio in-out ActLoopNT-in 2.872 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -138.86, 161.67 APE9-dihe-na 67.2, 154.51 APE8-dihe-in -70.63, 143.22 APE8-rot-in 290.43 APE67-dihe-in -57.31, -33.06 -57.15, -43.79 APE12-dist-out 14.027 APE11-dist-in 11.781 APE10-dist-in 7.978 APE9-dist-in 3.306 None PTR321 PTR321 XRAY 2.4 0.235 0.258 D 368 333 13 0 0 0 [[159, 479]] 1.0 6eir CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 6EIR — CMGC DYR1A_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6EIRA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 6EIRA Q13627 134 480 763.0 B6H:501 Type1 Inactive DFGin 7.393 14.795 BLAminus -125.18, 166.81 63.57, 86.84 -99.28, 31.63 287.87, 74.48 -70.6, -35.95 in-in in 8.782 Saltbr-in 2.895 HRD-in -63.53, -49.11 75.82, 12.8 in-in-out SNCiio in-out ActLoopNT-in 3.052 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -140.45, 163.14 APE9-dihe-na 68.93, 157.09 APE8-dihe-in -74.57, 134.52 APE8-rot-in 295.13 APE67-dihe-in -54.09, -35.75 -49.98, -47.46 APE12-dist-in 13.834 APE11-dist-in 11.859 APE10-dist-out 8.03 APE9-dist-in 3.209 None PTR321 PTR321 XRAY 2.4 0.235 0.258 A 368 342 5 0 0 0 [[159, 479]] 1.0 6eir Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6EIRB Q13627 133 480 763.0 B6H:501 Type1 Inactive DFGin 7.276 14.735 BLAminus -119.78, 174.81 68.91, 77.35 -98.17, 20.3 285.13, 87.39 -69.57, -27.99 in-in in 8.712 Saltbr-in 2.955 HRD-in -65.48, -40.64 68.84, 5.47 in-in-out SNCiio in-out ActLoopNT-in 2.731 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -144.55, 153.93 APE9-dihe-na 72.69, 153.36 APE8-dihe-in -69.83, 136.66 APE8-rot-in 293.84 APE67-dihe-in -59.39, -29.71 -51.99, -43.85 APE12-dist-out 14.548 APE11-dist-in 11.935 APE10-dist-out 8.485 APE9-dist-in 3.178 None PTR321 PTR321 XRAY 2.4 0.235 0.258 B 368 335 13 0 0 0 [[159, 479]] 1.0 6eir Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6EIRC Q13627 135 479 763.0 B6H:501 Type1 Inactive DFGin 7.412 15.039 BLAminus -130.82, 163.5 66.19, 85.94 -102.57, 28.49 281.77, 74.34 -75.43, -37.22 in-in in 8.512 Saltbr-in 2.752 HRD-in -65.03, -38.44 68.49, 5.65 in-in-out SNCiio in-out ActLoopNT-in 3.18 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -126.14, 166.06 APE9-dihe-na 64.03, 157.33 APE8-dihe-in -71.3, 146.96 APE8-rot-in 289.92 APE67-dihe-in -58.68, -32.01 -54.63, -47.82 APE12-dist-in 13.847 APE11-dist-in 11.909 APE10-dist-out 8.196 APE9-dist-in 3.124 None PTR321 PTR321 XRAY 2.4 0.235 0.258 C 368 333 12 0 0 0 [[159, 479]] 1.0 6eir Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 6EIRD Q13627 134 479 763.0 B6H:501 Type1 Inactive DFGin 7.412 15.089 BLAminus -128.73, 160.15 68.25, 89.2 -103.65, 29.38 289.19, 75.86 -72.84, -26.68 in-in in 8.657 Saltbr-in 2.915 HRD-in -59.93, -46.06 73.72, 10.04 in-in-out SNCiio in-out ActLoopNT-in 2.872 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -138.86, 161.67 APE9-dihe-na 67.2, 154.51 APE8-dihe-in -70.63, 143.22 APE8-rot-in 290.43 APE67-dihe-in -57.31, -33.06 -57.15, -43.79 APE12-dist-out 14.027 APE11-dist-in 11.781 APE10-dist-in 7.978 APE9-dist-in 3.306 None PTR321 PTR321 XRAY 2.4 0.235 0.258 D 368 333 13 0 0 0 [[159, 479]] 1.0 6eir Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 6EIR — CMGC DYR1A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name