PDB: 6CQH — CK1 VRK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6CQHB
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK1 VRK1_HUMAN 6CQHC Q99986 21 341 396.0 No_ligand No_ligand Inactive DFGin 7.983 14.851 BLAminus -118.07, 171.71 76.59, 94.42 -117.6, 18.62 300.15, 81.64 -66.87, -26.53 in-in in 8.206 Saltbr-in 2.634 HRD-in -92.02, -48.17 76.02, 0.45 in-in-out SNCiio in-out ActLoopNT-in 2.877 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, 7.71 APE9-dihe-na 82.96, -159.08 APE8-dihe-in -106.9, 123.02 APE8-rot-in 294.19 APE67-dihe-in -67.55, -22.98 -57.09, -40.82 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 10.275 APE9-dist-in 3.617 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.15 0.203 0.239 C 364 308 13 0 0 7 [[37, 326]] 1.0 6cqh CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1 261 261 196 197 198 200 202 71 83 87 174 176 175 177 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CQHA Q99986 20 341 396.0 F8Y:401 Type1 Inactive DFGin 8.008 14.763 BLAminus -111.2, 177.84 71.65, 92.99 -113.5, 20.29 298.38, 81.92 -64.24, -31.74 in-in in 7.987 Saltbr-in 2.719 HRD-in -84.71, -51.53 76.7, 2.57 in-in-out SNCiio in-out ActLoopNT-in 2.845 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, -17.4 APE9-dihe-na 78.26, -153.63 APE8-dihe-in -106.52, 129.33 APE8-rot-in 308.27 APE67-dihe-in -63.14, -26.0 -57.9, -46.8 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 10.171 APE9-dist-in 3.603 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.15 0.203 0.239 A 364 316 6 0 0 4 [[37, 326]] 1.0 6cqh CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1 261 261 196 197 198 200 202 71 83 87 174 176 175 177 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CQHB Q99986 22 341 396.0 F8Y:401 Type1 Inactive DFGin 8.571 14.534 BLAminus -111.21, 174.84 67.29, 87.72 -103.26, 28.03 297.11, 78.79 -65.77, -35.57 in-in in 7.65 Saltbr-in 2.873 HRD-in -90.46, -48.61 81.42, 3.81 in-in-out SNCiio in-out ActLoopNT-in 3.01 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -62.89, 150.55 APE9-dihe-na 106.38, -164.1 APE8-dihe-in -95.63, 117.11 APE8-rot-in 304.03 APE67-dihe-in -69.89, -25.07 -49.92, -44.26 APE12-dist-out 15.076 APE11-dist-in 13.613 APE10-dist-in 7.836 APE9-dist-in 4.087 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.15 0.203 0.239 B 364 316 4 0 0 0 [[37, 326]] 1.0 6cqh CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1 261 261 196 197 198 200 202 71 83 87 174 176 175 177 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CQHD Q99986 22 341 396.0 F8Y:401 Type1 Inactive DFGin 8.174 14.593 BLAminus -115.41, 176.27 64.66, 83.6 -96.31, 20.54 290.9, 78.1 -60.27, -27.19 in-in in 7.777 Saltbr-in 2.579 HRD-in -86.32, -49.88 80.57, -0.25 in-in-out SNCiio in-out ActLoopNT-in 3.007 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -66.57, 153.39 APE9-dihe-na 100.05, -169.76 APE8-dihe-in -95.11, 122.88 APE8-rot-in 296.22 APE67-dihe-in -70.56, -25.23 -58.65, -38.36 APE12-dist-out 14.86 APE11-dist-in 13.379 APE10-dist-in 7.56 APE9-dist-in 4.047 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.15 0.203 0.239 D 364 315 5 0 0 0 [[37, 326]] 1.0 6cqh CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1 261 261 196 197 198 200 202 71 83 87 174 176 175 177 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

PDB: 6CQH — CK1 VRK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6CQHB
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK1 VRK1_HUMAN 6CQHC Q99986 21 341 396.0 No_ligand No_ligand Inactive DFGin 7.983 14.851 BLAminus -118.07, 171.71 76.59, 94.42 -117.6, 18.62 300.15, 81.64 -66.87, -26.53 in-in in 8.206 Saltbr-in 2.634 HRD-in -92.02, -48.17 76.02, 0.45 in-in-out SNCiio in-out ActLoopNT-in 2.877 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, 7.71 APE9-dihe-na 82.96, -159.08 APE8-dihe-in -106.9, 123.02 APE8-rot-in 294.19 APE67-dihe-in -67.55, -22.98 -57.09, -40.82 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 10.275 APE9-dist-in 3.617 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.15 0.203 0.239 C 364 308 13 0 0 7 [[37, 326]] 1.0 6cqh Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1 261 261 196 197 198 200 202 71 83 87 174 176 175 177 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CQHA Q99986 20 341 396.0 F8Y:401 Type1 Inactive DFGin 8.008 14.763 BLAminus -111.2, 177.84 71.65, 92.99 -113.5, 20.29 298.38, 81.92 -64.24, -31.74 in-in in 7.987 Saltbr-in 2.719 HRD-in -84.71, -51.53 76.7, 2.57 in-in-out SNCiio in-out ActLoopNT-in 2.845 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, -17.4 APE9-dihe-na 78.26, -153.63 APE8-dihe-in -106.52, 129.33 APE8-rot-in 308.27 APE67-dihe-in -63.14, -26.0 -57.9, -46.8 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 10.171 APE9-dist-in 3.603 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.15 0.203 0.239 A 364 316 6 0 0 4 [[37, 326]] 1.0 6cqh Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1 261 261 196 197 198 200 202 71 83 87 174 176 175 177 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CQHB Q99986 22 341 396.0 F8Y:401 Type1 Inactive DFGin 8.571 14.534 BLAminus -111.21, 174.84 67.29, 87.72 -103.26, 28.03 297.11, 78.79 -65.77, -35.57 in-in in 7.65 Saltbr-in 2.873 HRD-in -90.46, -48.61 81.42, 3.81 in-in-out SNCiio in-out ActLoopNT-in 3.01 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -62.89, 150.55 APE9-dihe-na 106.38, -164.1 APE8-dihe-in -95.63, 117.11 APE8-rot-in 304.03 APE67-dihe-in -69.89, -25.07 -49.92, -44.26 APE12-dist-out 15.076 APE11-dist-in 13.613 APE10-dist-in 7.836 APE9-dist-in 4.087 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.15 0.203 0.239 B 364 316 4 0 0 0 [[37, 326]] 1.0 6cqh Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1 261 261 196 197 198 200 202 71 83 87 174 176 175 177 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CQHD Q99986 22 341 396.0 F8Y:401 Type1 Inactive DFGin 8.174 14.593 BLAminus -115.41, 176.27 64.66, 83.6 -96.31, 20.54 290.9, 78.1 -60.27, -27.19 in-in in 7.777 Saltbr-in 2.579 HRD-in -86.32, -49.88 80.57, -0.25 in-in-out SNCiio in-out ActLoopNT-in 3.007 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -66.57, 153.39 APE9-dihe-na 100.05, -169.76 APE8-dihe-in -95.11, 122.88 APE8-rot-in 296.22 APE67-dihe-in -70.56, -25.23 -58.65, -38.36 APE12-dist-out 14.86 APE11-dist-in 13.379 APE10-dist-in 7.56 APE9-dist-in 4.047 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.15 0.203 0.239 D 364 315 5 0 0 0 [[37, 326]] 1.0 6cqh Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1 261 261 196 197 198 200 202 71 83 87 174 176 175 177 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

PDB: 6CQH — CK1 VRK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name