PDB: 6CNX — CK1 VRK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6CNXA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK1 VRK1_HUMAN 6CNXA Q99986 20 341 396.0 F87:401 Type1 Inactive DFGin 8.0698 14.9683 BLAminus -118.67, 171.71 78.23, 84.24 -105.86, 18.22 298.1, 81.05 -66.18, -28.04 in-in in 8.0765 Saltbr-in 2.71 HRD-in -87.45, -49.38 77.51, -6.45 in-in-out SNCiio in-out ActLoopNT-in 2.9029 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -102.75, 3.42 APE9-dihe-na 88.52, -160.39 APE8-dihe-in -99.42, 119.25 APE8-rot-in 299.48 APE67-dihe-in -66.91, -26.62 -49.42, -43.65 APE12-dist-in 9.6231 APE11-dist-out 5.4796 APE10-dist-out 10.8125 APE9-dist-in 3.8365 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.0 0.188 0.211 A 364.0 322.0 0 35 35 0 [[37, 326]] 1.0 6cnx CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CNXB Q99986 21 341 396.0 F87:401 Type1.5_Back Inactive DFGin 8.3216 14.5468 BLAminus -115.62, 174.28 70.19, 90.35 -107.48, 27.1 294.52, 82.05 -63.68, -39.02 in-in in 7.7555 Saltbr-in 2.7564 HRD-in -89.7, -49.47 77.79, 1.89 in-in-out SNCiio in-out ActLoopNT-in 2.901 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -57.74, 153.84 APE9-dihe-na 94.87, -163.7 APE8-dihe-in -96.72, 118.51 APE8-rot-in 300.36 APE67-dihe-in -67.9, -26.38 -50.76, -42.64 APE12-dist-out 15.2417 APE11-dist-in 13.6818 APE10-dist-in 7.9708 APE9-dist-in 3.9974 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.0 0.188 0.211 B 364.0 311.0 10 35 35 0 [[37, 326]] 1.0 6cnx CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CNXC Q99986 21 341 396.0 FCS:401 Type1.5_Back Inactive DFGin 7.9287 14.959 BLAminus -117.97, 174.58 72.5, 95.69 -112.8, 14.63 298.18, 79.72 -53.03, -36.61 in-in in 8.2695 Saltbr-in 2.6981 HRD-in -80.65, -55.5 79.78, -0.52 in-in-out SNCiio in-out ActLoopNT-in 2.885 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -102.77, 2.4 APE9-dihe-na 89.21, -150.13 APE8-dihe-in -109.73, 119.46 APE8-rot-in 298.92 APE67-dihe-in -67.91, -25.71 -48.97, -43.76 APE12-dist-none 999.0 APE11-dist-out 5.5686 APE10-dist-out 10.8745 APE9-dist-in 3.8246 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.0 0.188 0.211 C 364.0 311.0 10 35 31 4 [[37, 326]] 1.0 6cnx CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CNXD Q99986 24 341 396.0 F87:401 Type1.5_Back Inactive DFGin 8.2679 14.5904 BLAminus -116.5, 175.45 68.07, 89.66 -105.26, 24.25 293.69, 81.55 -61.01, -28.01 in-in in 8.0432 Saltbr-in 2.7688 HRD-in -89.35, -52.24 76.81, 0.22 in-in-out SNCiio in-out ActLoopNT-in 2.8962 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -52.59, 151.44 APE9-dihe-na 93.38, -163.54 APE8-dihe-in -96.97, 118.76 APE8-rot-in 300.17 APE67-dihe-in -69.21, -25.49 -50.58, -42.99 APE12-dist-out 15.0907 APE11-dist-in 13.583 APE10-dist-in 7.8752 APE9-dist-in 4.121 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.0 0.188 0.211 D 364.0 312.0 6 35 35 0 [[37, 326]] 1.0 6cnx CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

PDB: 6CNX — CK1 VRK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6CNXA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK1 VRK1_HUMAN 6CNXA Q99986 20 341 396.0 F87:401 Type1 Inactive DFGin 8.0698 14.9683 BLAminus -118.67, 171.71 78.23, 84.24 -105.86, 18.22 298.1, 81.05 -66.18, -28.04 in-in in 8.0765 Saltbr-in 2.71 HRD-in -87.45, -49.38 77.51, -6.45 in-in-out SNCiio in-out ActLoopNT-in 2.9029 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -102.75, 3.42 APE9-dihe-na 88.52, -160.39 APE8-dihe-in -99.42, 119.25 APE8-rot-in 299.48 APE67-dihe-in -66.91, -26.62 -49.42, -43.65 APE12-dist-in 9.6231 APE11-dist-out 5.4796 APE10-dist-out 10.8125 APE9-dist-in 3.8365 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.0 0.188 0.211 A 364.0 322.0 0 35 35 0 [[37, 326]] 1.0 6cnx Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CNXB Q99986 21 341 396.0 F87:401 Type1.5_Back Inactive DFGin 8.3216 14.5468 BLAminus -115.62, 174.28 70.19, 90.35 -107.48, 27.1 294.52, 82.05 -63.68, -39.02 in-in in 7.7555 Saltbr-in 2.7564 HRD-in -89.7, -49.47 77.79, 1.89 in-in-out SNCiio in-out ActLoopNT-in 2.901 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -57.74, 153.84 APE9-dihe-na 94.87, -163.7 APE8-dihe-in -96.72, 118.51 APE8-rot-in 300.36 APE67-dihe-in -67.9, -26.38 -50.76, -42.64 APE12-dist-out 15.2417 APE11-dist-in 13.6818 APE10-dist-in 7.9708 APE9-dist-in 3.9974 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.0 0.188 0.211 B 364.0 311.0 10 35 35 0 [[37, 326]] 1.0 6cnx Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CNXC Q99986 21 341 396.0 FCS:401 Type1.5_Back Inactive DFGin 7.9287 14.959 BLAminus -117.97, 174.58 72.5, 95.69 -112.8, 14.63 298.18, 79.72 -53.03, -36.61 in-in in 8.2695 Saltbr-in 2.6981 HRD-in -80.65, -55.5 79.78, -0.52 in-in-out SNCiio in-out ActLoopNT-in 2.885 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -102.77, 2.4 APE9-dihe-na 89.21, -150.13 APE8-dihe-in -109.73, 119.46 APE8-rot-in 298.92 APE67-dihe-in -67.91, -25.71 -48.97, -43.76 APE12-dist-none 999.0 APE11-dist-out 5.5686 APE10-dist-out 10.8745 APE9-dist-in 3.8246 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.0 0.188 0.211 C 364.0 311.0 10 35 31 4 [[37, 326]] 1.0 6cnx Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CNXD Q99986 24 341 396.0 F87:401 Type1.5_Back Inactive DFGin 8.2679 14.5904 BLAminus -116.5, 175.45 68.07, 89.66 -105.26, 24.25 293.69, 81.55 -61.01, -28.01 in-in in 8.0432 Saltbr-in 2.7688 HRD-in -89.35, -52.24 76.81, 0.22 in-in-out SNCiio in-out ActLoopNT-in 2.8962 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -52.59, 151.44 APE9-dihe-na 93.38, -163.54 APE8-dihe-in -96.97, 118.76 APE8-rot-in 300.17 APE67-dihe-in -69.21, -25.49 -50.58, -42.99 APE12-dist-out 15.0907 APE11-dist-in 13.583 APE10-dist-in 7.8752 APE9-dist-in 4.121 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.0 0.188 0.211 D 364.0 312.0 6 35 35 0 [[37, 326]] 1.0 6cnx Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

PDB: 6CNX — CK1 VRK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name