PDB: 6CMM — CK1 VRK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6CMMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK1 VRK1_HUMAN 6CMMA Q99986 20 341 396.0 No_ligand No_ligand Inactive DFGin 7.939 14.8529 BLAminus -118.01, 179.55 70.25, 94.14 -114.09, 19.03 296.97, 80.28 -64.11, -27.16 in-in in 7.9867 Saltbr-in 2.7237 HRD-in -70.61, -48.88 72.27, 0.35 in-in-out SNCiio in-out ActLoopNT-in 2.8353 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -115.61, 6.25 APE9-dihe-na 83.26, -156.76 APE8-dihe-in -101.59, 132.95 APE8-rot-in 301.05 APE67-dihe-in -61.96, -26.2 -62.18, -45.9 APE12-dist-in 9.4052 APE11-dist-out 5.5788 APE10-dist-out 10.7856 APE9-dist-in 3.7965 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.192 0.222 A 364.0 318.0 4 35 35 0 [[37, 326]] 1.0 6cmm CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CMMC Q99986 21 341 396.0 No_ligand No_ligand Inactive DFGin 7.9134 14.8381 BLAminus -118.19, 172.22 77.38, 94.72 -118.56, 19.82 299.14, 81.41 -62.89, -28.04 in-in in 8.0902 Saltbr-in 2.6585 HRD-in -85.44, -49.56 76.52, 1.18 in-in-out SNCiio in-out ActLoopNT-in 2.8166 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -126.71, 22.14 APE9-dihe-na 66.49, -154.73 APE8-dihe-in -106.73, 121.33 APE8-rot-in 297.11 APE67-dihe-in -65.73, -23.75 -52.02, -44.91 APE12-dist-in 9.3574 APE11-dist-out 5.6204 APE10-dist-out 10.6221 APE9-dist-in 3.6326 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.192 0.222 C 364.0 316.0 5 35 35 0 [[37, 326]] 1.0 6cmm CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CMMB Q99986 23 341 396.0 F7D:401 Type1 Inactive DFGin 8.4756 14.4828 BLAminus -115.06, 177.55 64.23, 84.91 -98.08, 23.22 291.58, 82.57 -66.41, -28.16 in-in in 7.6013 Saltbr-in 2.8968 HRD-in -88.21, -48.16 77.0, 4.0 in-in-out SNCiio in-out ActLoopNT-in 2.9589 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -59.62, 146.4 APE9-dihe-na 107.7, -170.45 APE8-dihe-in -90.13, 117.89 APE8-rot-in 302.22 APE67-dihe-in -67.83, -25.02 -51.39, -42.58 APE12-dist-out 15.0374 APE11-dist-in 13.4506 APE10-dist-in 7.738 APE9-dist-in 4.0653 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.192 0.222 B 364.0 310.0 9 35 35 0 [[37, 326]] 1.0 6cmm CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CMMD Q99986 23 341 396.0 F7D:401 Type1 Inactive DFGin 8.3025 14.5765 BLAminus -120.35, -178.73 57.57, 80.72 -90.78, 22.63 288.79, 76.0 -64.84, -22.8 in-in in 7.7939 Saltbr-in 2.9946 HRD-in -88.03, -46.07 76.94, -0.28 in-in-out SNCiio in-out ActLoopNT-in 2.9087 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -59.16, 154.16 APE9-dihe-na 94.99, -165.63 APE8-dihe-in -97.55, 123.52 APE8-rot-in 296.28 APE67-dihe-in -67.77, -24.35 -58.36, -42.41 APE12-dist-out 14.924 APE11-dist-in 13.1932 APE10-dist-in 7.4334 APE9-dist-in 4.1656 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.192 0.222 D 364.0 315.0 4 35 35 0 [[37, 326]] 1.0 6cmm CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

PDB: 6CMM — CK1 VRK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6CMMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK1 VRK1_HUMAN 6CMMA Q99986 20 341 396.0 No_ligand No_ligand Inactive DFGin 7.939 14.8529 BLAminus -118.01, 179.55 70.25, 94.14 -114.09, 19.03 296.97, 80.28 -64.11, -27.16 in-in in 7.9867 Saltbr-in 2.7237 HRD-in -70.61, -48.88 72.27, 0.35 in-in-out SNCiio in-out ActLoopNT-in 2.8353 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -115.61, 6.25 APE9-dihe-na 83.26, -156.76 APE8-dihe-in -101.59, 132.95 APE8-rot-in 301.05 APE67-dihe-in -61.96, -26.2 -62.18, -45.9 APE12-dist-in 9.4052 APE11-dist-out 5.5788 APE10-dist-out 10.7856 APE9-dist-in 3.7965 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.192 0.222 A 364.0 318.0 4 35 35 0 [[37, 326]] 1.0 6cmm Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CMMC Q99986 21 341 396.0 No_ligand No_ligand Inactive DFGin 7.9134 14.8381 BLAminus -118.19, 172.22 77.38, 94.72 -118.56, 19.82 299.14, 81.41 -62.89, -28.04 in-in in 8.0902 Saltbr-in 2.6585 HRD-in -85.44, -49.56 76.52, 1.18 in-in-out SNCiio in-out ActLoopNT-in 2.8166 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -126.71, 22.14 APE9-dihe-na 66.49, -154.73 APE8-dihe-in -106.73, 121.33 APE8-rot-in 297.11 APE67-dihe-in -65.73, -23.75 -52.02, -44.91 APE12-dist-in 9.3574 APE11-dist-out 5.6204 APE10-dist-out 10.6221 APE9-dist-in 3.6326 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.192 0.222 C 364.0 316.0 5 35 35 0 [[37, 326]] 1.0 6cmm Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CMMB Q99986 23 341 396.0 F7D:401 Type1 Inactive DFGin 8.4756 14.4828 BLAminus -115.06, 177.55 64.23, 84.91 -98.08, 23.22 291.58, 82.57 -66.41, -28.16 in-in in 7.6013 Saltbr-in 2.8968 HRD-in -88.21, -48.16 77.0, 4.0 in-in-out SNCiio in-out ActLoopNT-in 2.9589 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -59.62, 146.4 APE9-dihe-na 107.7, -170.45 APE8-dihe-in -90.13, 117.89 APE8-rot-in 302.22 APE67-dihe-in -67.83, -25.02 -51.39, -42.58 APE12-dist-out 15.0374 APE11-dist-in 13.4506 APE10-dist-in 7.738 APE9-dist-in 4.0653 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.192 0.222 B 364.0 310.0 9 35 35 0 [[37, 326]] 1.0 6cmm Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CMMD Q99986 23 341 396.0 F7D:401 Type1 Inactive DFGin 8.3025 14.5765 BLAminus -120.35, -178.73 57.57, 80.72 -90.78, 22.63 288.79, 76.0 -64.84, -22.8 in-in in 7.7939 Saltbr-in 2.9946 HRD-in -88.03, -46.07 76.94, -0.28 in-in-out SNCiio in-out ActLoopNT-in 2.9087 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -59.16, 154.16 APE9-dihe-na 94.99, -165.63 APE8-dihe-in -97.55, 123.52 APE8-rot-in 296.28 APE67-dihe-in -67.77, -24.35 -58.36, -42.41 APE12-dist-out 14.924 APE11-dist-in 13.1932 APE10-dist-in 7.4334 APE9-dist-in 4.1656 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.192 0.222 D 364.0 315.0 4 35 35 0 [[37, 326]] 1.0 6cmm Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

PDB: 6CMM — CK1 VRK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name