PDB: 6BRU — CK1 VRK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6BRUA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK1 VRK1_HUMAN 6BRUA Q99986 20 341 396.0 No_ligand No_ligand Inactive DFGin 8.0334 14.707 BLAminus -117.66, 174.8 73.4, 90.42 -111.17, 18.43 297.57, 83.73 -62.66, -32.45 in-in in 7.7505 Saltbr-in 2.7232 HRD-in -89.4, -48.02 76.76, 0.18 in-in-out SNCiio in-out ActLoopNT-in 2.9094 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -112.07, 4.26 APE9-dihe-na 85.33, -161.74 APE8-dihe-in -100.33, 121.11 APE8-rot-in 296.71 APE67-dihe-in -67.79, -25.01 -53.75, -41.68 APE12-dist-in 9.256 APE11-dist-out 5.4967 APE10-dist-out 10.929 APE9-dist-in 3.8042 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 1.8 0.196 0.214 A 364.0 322.0 0 35 35 0 [[37, 326]] 1.0 6bru CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BRUC Q99986 21 341 396.0 No_ligand No_ligand Inactive DFGin 7.9847 14.9619 BLAminus -117.45, 175.22 72.9, 90.95 -111.5, 17.79 298.09, 83.36 -63.53, -31.92 in-in in 8.0282 Saltbr-in 2.732 HRD-in -88.93, -48.21 76.94, 0.57 in-in-out SNCiio in-out ActLoopNT-in 2.8702 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -112.0, 3.87 APE9-dihe-na 86.79, -161.39 APE8-dihe-in -100.72, 120.61 APE8-rot-in 298.11 APE67-dihe-in -68.1, -24.22 -53.45, -41.86 APE12-dist-in 9.1948 APE11-dist-out 5.5096 APE10-dist-out 10.9601 APE9-dist-in 3.808 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 1.8 0.196 0.214 C 364.0 315.0 6 35 35 0 [[37, 326]] 1.0 6bru CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BRUB Q99986 23 341 396.0 E5M:401 Type1.5_Back Inactive DFGin 8.3574 14.7479 BLAminus -116.05, 174.64 73.11, 90.37 -112.13, 20.06 298.39, 84.27 -63.74, -27.85 in-in in 8.0769 Saltbr-in 2.7276 HRD-in -90.47, -48.07 75.98, 2.3 in-in-out SNCiio in-out ActLoopNT-in 2.89 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooi APE10-dihe-na -62.64, 163.66 APE9-dihe-na 89.79, -163.11 APE8-dihe-in -97.38, 120.62 APE8-rot-in 298.71 APE67-dihe-in -69.4, -24.42 -55.79, -40.6 APE12-dist-out 15.5991 APE11-dist-out 14.2978 APE10-dist-out 8.5755 APE9-dist-in 4.0236 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 1.8 0.196 0.214 B 364.0 301.0 18 35 35 0 [[37, 326]] 1.0 6bru CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BRUD Q99986 22 341 396.0 E5M:401 Type1.5_Back Inactive DFGin 8.2362 14.6243 BLAminus -117.89, 173.75 70.48, 89.16 -108.83, 20.66 296.08, 83.19 -48.29, -34.49 in-in in 8.0302 Saltbr-in 2.8773 HRD-in -89.48, -48.25 74.72, 2.08 in-in-out SNCiio in-out ActLoopNT-in 2.894 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -62.24, 162.75 APE9-dihe-na 91.76, -163.66 APE8-dihe-in -96.35, 120.51 APE8-rot-in 298.54 APE67-dihe-in -70.22, -23.54 -55.93, -40.24 APE12-dist-out 15.2061 APE11-dist-in 13.8461 APE10-dist-out 8.1052 APE9-dist-in 4.0579 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 1.8 0.196 0.214 D 364.0 311.0 9 35 35 0 [[37, 326]] 1.0 6bru CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

PDB: 6BRU — CK1 VRK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6BRUA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK1 VRK1_HUMAN 6BRUA Q99986 20 341 396.0 No_ligand No_ligand Inactive DFGin 8.0334 14.707 BLAminus -117.66, 174.8 73.4, 90.42 -111.17, 18.43 297.57, 83.73 -62.66, -32.45 in-in in 7.7505 Saltbr-in 2.7232 HRD-in -89.4, -48.02 76.76, 0.18 in-in-out SNCiio in-out ActLoopNT-in 2.9094 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -112.07, 4.26 APE9-dihe-na 85.33, -161.74 APE8-dihe-in -100.33, 121.11 APE8-rot-in 296.71 APE67-dihe-in -67.79, -25.01 -53.75, -41.68 APE12-dist-in 9.256 APE11-dist-out 5.4967 APE10-dist-out 10.929 APE9-dist-in 3.8042 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 1.8 0.196 0.214 A 364.0 322.0 0 35 35 0 [[37, 326]] 1.0 6bru Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BRUC Q99986 21 341 396.0 No_ligand No_ligand Inactive DFGin 7.9847 14.9619 BLAminus -117.45, 175.22 72.9, 90.95 -111.5, 17.79 298.09, 83.36 -63.53, -31.92 in-in in 8.0282 Saltbr-in 2.732 HRD-in -88.93, -48.21 76.94, 0.57 in-in-out SNCiio in-out ActLoopNT-in 2.8702 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -112.0, 3.87 APE9-dihe-na 86.79, -161.39 APE8-dihe-in -100.72, 120.61 APE8-rot-in 298.11 APE67-dihe-in -68.1, -24.22 -53.45, -41.86 APE12-dist-in 9.1948 APE11-dist-out 5.5096 APE10-dist-out 10.9601 APE9-dist-in 3.808 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 1.8 0.196 0.214 C 364.0 315.0 6 35 35 0 [[37, 326]] 1.0 6bru Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BRUB Q99986 23 341 396.0 E5M:401 Type1.5_Back Inactive DFGin 8.3574 14.7479 BLAminus -116.05, 174.64 73.11, 90.37 -112.13, 20.06 298.39, 84.27 -63.74, -27.85 in-in in 8.0769 Saltbr-in 2.7276 HRD-in -90.47, -48.07 75.98, 2.3 in-in-out SNCiio in-out ActLoopNT-in 2.89 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooi APE10-dihe-na -62.64, 163.66 APE9-dihe-na 89.79, -163.11 APE8-dihe-in -97.38, 120.62 APE8-rot-in 298.71 APE67-dihe-in -69.4, -24.42 -55.79, -40.6 APE12-dist-out 15.5991 APE11-dist-out 14.2978 APE10-dist-out 8.5755 APE9-dist-in 4.0236 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 1.8 0.196 0.214 B 364.0 301.0 18 35 35 0 [[37, 326]] 1.0 6bru Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BRUD Q99986 22 341 396.0 E5M:401 Type1.5_Back Inactive DFGin 8.2362 14.6243 BLAminus -117.89, 173.75 70.48, 89.16 -108.83, 20.66 296.08, 83.19 -48.29, -34.49 in-in in 8.0302 Saltbr-in 2.8773 HRD-in -89.48, -48.25 74.72, 2.08 in-in-out SNCiio in-out ActLoopNT-in 2.894 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -62.24, 162.75 APE9-dihe-na 91.76, -163.66 APE8-dihe-in -96.35, 120.51 APE8-rot-in 298.54 APE67-dihe-in -70.22, -23.54 -55.93, -40.24 APE12-dist-out 15.2061 APE11-dist-in 13.8461 APE10-dist-out 8.1052 APE9-dist-in 4.0579 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 1.8 0.196 0.214 D 364.0 311.0 9 35 35 0 [[37, 326]] 1.0 6bru Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

PDB: 6BRU — CK1 VRK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name