PDB: 6AGX — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6AGXB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 6AGXA P21802 467 764 821.0 9WX:800 Type1.5_Back Inactive DFGin 6.3853 13.7705 BLAminus -135.61, -178.23 50.32, 94.72 -100.36, 28.49 297.32, 121.17 -57.47, -52.54 in-out in 7.9997 Saltbr-out 3.657 HRD-in -93.88, -57.68 78.68, 6.68 out-in-in SNCoii in-in ActLoopNT-in 2.9546 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -105.5, 54.14 APE9-dihe-in -114.81, 139.22 APE8-dihe-in -71.75, 130.63 APE8-rot-na 345.91 APE67-dihe-in -76.18, -12.01 -73.34, -35.43 APE12-dist-na 13.5302 APE11-dist-na 9.0647 APE10-dist-na 7.568 APE9-dist-in 4.5955 A628T PTR586,PTR588,PTR656,PTR657 PTR586,PTR588,PTR656,PTR657 XRAY 2.95 0.254 0.298 A 298.0 285.0 13 30 25 5 [[481, 759]] 1.0 6agx TYR_FGFR2_HUMAN TYR 1.2e-103 351.9 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXB P21802 467 764 821.0 9WX:800 Type1.5_Back Inactive DFGin 6.4052 14.0255 BLAminus -135.35, -176.95 51.01, 93.04 -100.6, 27.53 298.31, 119.25 -60.39, -50.86 in-out in 7.9614 Saltbr-out 4.3798 HRD-in -94.17, -57.95 78.91, 4.09 out-in-out SNCoio in-out ActLoopNT-in 2.9492 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -102.86, 49.42 APE9-dihe-in -113.92, 143.72 APE8-dihe-in -70.47, 130.2 APE8-rot-na 344.64 APE67-dihe-in -74.99, -12.99 -75.16, -33.86 APE12-dist-na 14.5033 APE11-dist-na 9.8559 APE10-dist-na 7.7325 APE9-dist-in 4.6967 A628T PTR586,PTR588,PTR656,PTR657 PTR586,PTR588,PTR656,PTR657 XRAY 2.95 0.254 0.298 B 298.0 298.0 0 30 30 0 [[481, 759]] 1.0 6agx TYR_FGFR2_HUMAN TYR 1.2e-103 351.9 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXC P21802 467 764 821.0 9WX:800 Type1.5_Back Inactive DFGin 6.3902 13.8027 BLAminus -136.28, -175.68 48.02, 94.4 -101.25, 28.5 296.6, 120.3 -58.43, -51.67 in-out in 7.9156 Saltbr-out 3.6615 HRD-in -93.94, -57.46 79.08, 5.82 out-in-in SNCoii in-in ActLoopNT-in 2.9508 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -86.39, 66.84 APE9-dihe-in -120.25, 138.55 APE8-dihe-in -72.11, 130.82 APE8-rot-na 346.01 APE67-dihe-in -76.61, -11.72 -72.7, -35.99 APE12-dist-na 14.1409 APE11-dist-na 9.1912 APE10-dist-na 7.7003 APE9-dist-in 4.6998 A628T PTR586,PTR588,PTR656,PTR657 PTR586,PTR588,PTR656,PTR657 XRAY 2.95 0.254 0.298 C 298.0 284.0 14 30 25 5 [[481, 759]] 1.0 6agx TYR_FGFR2_HUMAN TYR 1.2e-103 351.9 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXD P21802 467 764 821.0 9WX:800 Type1.5_Back Inactive DFGin 6.3552 13.9404 BLAminus -136.3, -175.46 49.29, 93.64 -101.17, 27.37 298.51, 119.67 -59.92, -50.84 in-out in 7.9748 Saltbr-out 3.6895 HRD-in -94.2, -57.48 79.52, 3.16 out-in-out SNCoio in-out ActLoopNT-in 2.9496 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -103.04, 47.47 APE9-dihe-in -113.88, 141.66 APE8-dihe-in -70.17, 130.94 APE8-rot-na 346.46 APE67-dihe-in -73.96, -13.6 -74.55, -33.23 APE12-dist-na 14.2829 APE11-dist-na 9.8199 APE10-dist-na 7.6084 APE9-dist-in 4.719 A628T PTR586,PTR588,PTR656,PTR657 PTR586,PTR588,PTR656,PTR657 XRAY 2.95 0.254 0.298 D 298.0 298.0 0 30 30 0 [[481, 759]] 1.0 6agx TYR_FGFR2_HUMAN TYR 1.2e-103 351.9 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 6AGX — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6AGXB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 6AGXA P21802 467 764 821.0 9WX:800 Type1.5_Back Inactive DFGin 6.3853 13.7705 BLAminus -135.61, -178.23 50.32, 94.72 -100.36, 28.49 297.32, 121.17 -57.47, -52.54 in-out in 7.9997 Saltbr-out 3.657 HRD-in -93.88, -57.68 78.68, 6.68 out-in-in SNCoii in-in ActLoopNT-in 2.9546 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -105.5, 54.14 APE9-dihe-in -114.81, 139.22 APE8-dihe-in -71.75, 130.63 APE8-rot-na 345.91 APE67-dihe-in -76.18, -12.01 -73.34, -35.43 APE12-dist-na 13.5302 APE11-dist-na 9.0647 APE10-dist-na 7.568 APE9-dist-in 4.5955 A628T PTR586,PTR588,PTR656,PTR657 PTR586,PTR588,PTR656,PTR657 XRAY 2.95 0.254 0.298 A 298.0 285.0 13 30 25 5 [[481, 759]] 1.0 6agx Homo sapiens TYR_FGFR2_HUMAN TYR 1.2e-103 351.9 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXB P21802 467 764 821.0 9WX:800 Type1.5_Back Inactive DFGin 6.4052 14.0255 BLAminus -135.35, -176.95 51.01, 93.04 -100.6, 27.53 298.31, 119.25 -60.39, -50.86 in-out in 7.9614 Saltbr-out 4.3798 HRD-in -94.17, -57.95 78.91, 4.09 out-in-out SNCoio in-out ActLoopNT-in 2.9492 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -102.86, 49.42 APE9-dihe-in -113.92, 143.72 APE8-dihe-in -70.47, 130.2 APE8-rot-na 344.64 APE67-dihe-in -74.99, -12.99 -75.16, -33.86 APE12-dist-na 14.5033 APE11-dist-na 9.8559 APE10-dist-na 7.7325 APE9-dist-in 4.6967 A628T PTR586,PTR588,PTR656,PTR657 PTR586,PTR588,PTR656,PTR657 XRAY 2.95 0.254 0.298 B 298.0 298.0 0 30 30 0 [[481, 759]] 1.0 6agx Homo sapiens TYR_FGFR2_HUMAN TYR 1.2e-103 351.9 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXC P21802 467 764 821.0 9WX:800 Type1.5_Back Inactive DFGin 6.3902 13.8027 BLAminus -136.28, -175.68 48.02, 94.4 -101.25, 28.5 296.6, 120.3 -58.43, -51.67 in-out in 7.9156 Saltbr-out 3.6615 HRD-in -93.94, -57.46 79.08, 5.82 out-in-in SNCoii in-in ActLoopNT-in 2.9508 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -86.39, 66.84 APE9-dihe-in -120.25, 138.55 APE8-dihe-in -72.11, 130.82 APE8-rot-na 346.01 APE67-dihe-in -76.61, -11.72 -72.7, -35.99 APE12-dist-na 14.1409 APE11-dist-na 9.1912 APE10-dist-na 7.7003 APE9-dist-in 4.6998 A628T PTR586,PTR588,PTR656,PTR657 PTR586,PTR588,PTR656,PTR657 XRAY 2.95 0.254 0.298 C 298.0 284.0 14 30 25 5 [[481, 759]] 1.0 6agx Homo sapiens TYR_FGFR2_HUMAN TYR 1.2e-103 351.9 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXD P21802 467 764 821.0 9WX:800 Type1.5_Back Inactive DFGin 6.3552 13.9404 BLAminus -136.3, -175.46 49.29, 93.64 -101.17, 27.37 298.51, 119.67 -59.92, -50.84 in-out in 7.9748 Saltbr-out 3.6895 HRD-in -94.2, -57.48 79.52, 3.16 out-in-out SNCoio in-out ActLoopNT-in 2.9496 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -103.04, 47.47 APE9-dihe-in -113.88, 141.66 APE8-dihe-in -70.17, 130.94 APE8-rot-na 346.46 APE67-dihe-in -73.96, -13.6 -74.55, -33.23 APE12-dist-na 14.2829 APE11-dist-na 9.8199 APE10-dist-na 7.6084 APE9-dist-in 4.719 A628T PTR586,PTR588,PTR656,PTR657 PTR586,PTR588,PTR656,PTR657 XRAY 2.95 0.254 0.298 D 298.0 298.0 0 30 30 0 [[481, 759]] 1.0 6agx Homo sapiens TYR_FGFR2_HUMAN TYR 1.2e-103 351.9 1.0 260.0 260.0 643 644 645 647 649 517 534 538 623 625 624 626.0 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 6AGX — TYR FGFR2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name