PDB: 6AAK — TYR JAK3_HUMAN

Total number of chains: 4
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6AAKB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN 6AAKA P52333 815 1098 1124.0 9T6:1201 Type1 Inactive DFGin 6.4258 14.4877 BLAminus -141.28, -175.48 60.31, 80.99 -97.75, 30.98 284.74, 77.33 -61.02, -46.05 in-in in 8.5254 Saltbr-in 2.67 HRD-in -75.62, -45.99 77.6, -18.1 in-in-out SNCiio in-out ActLoopNT-in 2.7362 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -74.2, -11.07 APE9-dihe-in -68.95, 155.07 APE8-dihe-in -47.57, 131.1 APE8-rot-na 329.72 APE67-dihe-in -73.4, -26.9 -66.76, -22.48 APE12-dist-na 11.9929 APE11-dist-na 8.6734 APE10-dist-na 11.3981 APE9-dist-in 7.4704 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.67 0.269 0.326 A 287.0 277.0 7 31 31 0 [[521, 779], [822, 1097]] 2.0 6aak TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6AAKB P52333 815 1100 1124.0 9T6:1201 Type1 Inactive DFGin 6.549 14.3135 BLAminus -132.57, -171.05 56.03, 83.09 -98.42, 24.6 281.38, 75.24 -63.47, -40.11 in-in in 8.0358 Saltbr-in 2.7546 HRD-in -65.5, -48.18 78.33, -13.38 in-in-out SNCiio in-out ActLoopNT-in 2.9074 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -123.61, -28.55 APE9-dihe-in -64.46, 151.35 APE8-dihe-in -40.19, 130.42 APE8-rot-na 326.93 APE67-dihe-in -77.17, -14.56 -72.74, -10.57 APE12-dist-na 13.1081 APE11-dist-na 9.526 APE10-dist-na 10.0845 APE9-dist-in 7.2029 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.67 0.269 0.326 B 287.0 285.0 1 31 31 0 [[521, 779], [822, 1097]] 2.0 6aak TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6AAKC P52333 814 1099 1124.0 9T6:1201 Type1 Active DFGin 6.7877 14.6346 BLAminus -114.47, 172.4 69.03, 86.81 -107.19, 29.58 286.76, 78.99 -58.47, -55.72 in-in in 8.2406 Saltbr-in 2.7237 HRD-in -89.94, -41.82 71.73, -3.81 in-in-in SNCiii in-in ActLoopNT-in 2.7832 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.85, 76.94 APE9-dihe-in -171.36, 163.86 APE8-dihe-in -58.47, 128.31 APE8-rot-na 338.62 APE67-dihe-in -73.56, -5.95 -79.88, -15.99 APE12-dist-na 12.9746 APE11-dist-na 9.2183 APE10-dist-na 10.3986 APE9-dist-in 7.7513 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.67 0.269 0.326 C 287.0 276.0 10 31 31 0 [[521, 779], [822, 1097]] 2.0 6aak TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6AAKD P52333 814 1098 1124.0 9T6:1201 Type1 None DFGin 6.3309 14.1383 BLAminus -145.03, 168.99 56.55, 97.11 -103.75, 32.24 293.47, 81.71 -62.01, -33.71 in-in in 8.0179 Saltbr-in 2.8556 HRD-in -76.49, -42.81 76.74, -36.27 in-in-none SNCiin in-none ActLoopNT-in 2.7662 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 72.65 APE8-dihe-in -50.29, 134.06 APE8-rot-na 332.19 APE67-dihe-in -63.85, -16.03 -70.13, -20.9 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.3842 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.67 0.269 0.326 D 287.0 268.0 17 31 26 5 [[521, 779], [822, 1097]] 2.0 6aak TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

PDB: 6AAK — TYR JAK3_HUMAN

Total number of chains: 4
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6AAKB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN 6AAKA P52333 815 1098 1124.0 9T6:1201 Type1 Inactive DFGin 6.4258 14.4877 BLAminus -141.28, -175.48 60.31, 80.99 -97.75, 30.98 284.74, 77.33 -61.02, -46.05 in-in in 8.5254 Saltbr-in 2.67 HRD-in -75.62, -45.99 77.6, -18.1 in-in-out SNCiio in-out ActLoopNT-in 2.7362 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -74.2, -11.07 APE9-dihe-in -68.95, 155.07 APE8-dihe-in -47.57, 131.1 APE8-rot-na 329.72 APE67-dihe-in -73.4, -26.9 -66.76, -22.48 APE12-dist-na 11.9929 APE11-dist-na 8.6734 APE10-dist-na 11.3981 APE9-dist-in 7.4704 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.67 0.269 0.326 A 287.0 277.0 7 31 31 0 [[521, 779], [822, 1097]] 2.0 6aak Homo sapiens TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6AAKB P52333 815 1100 1124.0 9T6:1201 Type1 Inactive DFGin 6.549 14.3135 BLAminus -132.57, -171.05 56.03, 83.09 -98.42, 24.6 281.38, 75.24 -63.47, -40.11 in-in in 8.0358 Saltbr-in 2.7546 HRD-in -65.5, -48.18 78.33, -13.38 in-in-out SNCiio in-out ActLoopNT-in 2.9074 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -123.61, -28.55 APE9-dihe-in -64.46, 151.35 APE8-dihe-in -40.19, 130.42 APE8-rot-na 326.93 APE67-dihe-in -77.17, -14.56 -72.74, -10.57 APE12-dist-na 13.1081 APE11-dist-na 9.526 APE10-dist-na 10.0845 APE9-dist-in 7.2029 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.67 0.269 0.326 B 287.0 285.0 1 31 31 0 [[521, 779], [822, 1097]] 2.0 6aak Homo sapiens TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6AAKC P52333 814 1099 1124.0 9T6:1201 Type1 Active DFGin 6.7877 14.6346 BLAminus -114.47, 172.4 69.03, 86.81 -107.19, 29.58 286.76, 78.99 -58.47, -55.72 in-in in 8.2406 Saltbr-in 2.7237 HRD-in -89.94, -41.82 71.73, -3.81 in-in-in SNCiii in-in ActLoopNT-in 2.7832 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.85, 76.94 APE9-dihe-in -171.36, 163.86 APE8-dihe-in -58.47, 128.31 APE8-rot-na 338.62 APE67-dihe-in -73.56, -5.95 -79.88, -15.99 APE12-dist-na 12.9746 APE11-dist-na 9.2183 APE10-dist-na 10.3986 APE9-dist-in 7.7513 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.67 0.269 0.326 C 287.0 276.0 10 31 31 0 [[521, 779], [822, 1097]] 2.0 6aak Homo sapiens TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6AAKD P52333 814 1098 1124.0 9T6:1201 Type1 None DFGin 6.3309 14.1383 BLAminus -145.03, 168.99 56.55, 97.11 -103.75, 32.24 293.47, 81.71 -62.01, -33.71 in-in in 8.0179 Saltbr-in 2.8556 HRD-in -76.49, -42.81 76.74, -36.27 in-in-none SNCiin in-none ActLoopNT-in 2.7662 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 72.65 APE8-dihe-in -50.29, 134.06 APE8-rot-na 332.19 APE67-dihe-in -63.85, -16.03 -70.13, -20.9 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.3842 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.67 0.269 0.326 D 287.0 268.0 17 31 26 5 [[521, 779], [822, 1097]] 2.0 6aak Homo sapiens TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

PDB: 6AAK — TYR JAK3_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name