PDB: 6AAJ — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6AAJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6AAJA O60674 843 1130 1132.0 9T6:1201 Type1 Active DFGin 6.5381 14.4891 BLAminus -115.63, -164.58 40.59, 91.02 -103.17, 27.63 288.93, 89.27 -64.3, -31.13 in-in in 8.2901 Saltbr-in 3.264 HRD-in -73.79, -50.75 76.22, -8.05 in-in-in SNCiii in-in ActLoopNT-in 2.6624 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -60.45, 121.7 APE9-dihe-in -116.64, 165.17 APE8-dihe-in -82.47, 75.26 APE8-rot-na 26.67 APE67-dihe-in -77.47, -9.05 -66.38, -30.21 APE12-dist-na 11.3039 APE11-dist-na 10.8972 APE10-dist-na 12.893 APE9-dist-in 7.8569 K943A,K945A PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.37 0.211 0.262 A 299.0 283.0 5 31 31 0 [[545, 807], [849, 1125]] 2.0 6aaj TYR_JAK2-2_HUMAN TYR 1.1e-86 296.3 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6AAJB O60674 843 1131 1132.0 9T6:1201 Type1 Active DFGin 6.5453 14.3954 BLAminus -118.96, -159.53 45.76, 82.33 -100.65, 20.72 287.12, 93.43 -66.06, -21.73 in-in in 8.5436 Saltbr-in 2.8436 HRD-in -65.44, -45.07 71.55, -13.22 in-in-in SNCiii in-in ActLoopNT-in 2.8819 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -115.56, 105.36 APE9-dihe-in -102.08, 153.39 APE8-dihe-in -76.19, 74.45 APE8-rot-na 31.79 APE67-dihe-in -76.6, 0.02 -66.92, -30.87 APE12-dist-na 999.0 APE11-dist-na 12.1768 APE10-dist-na 12.8016 APE9-dist-in 7.8139 K943A,K945A PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.37 0.211 0.262 B 299.0 274.0 15 31 29 2 [[545, 807], [849, 1125]] 2.0 6aaj TYR_JAK2-2_HUMAN TYR 1.1e-86 296.3 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6AAJ — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6AAJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6AAJA O60674 843 1130 1132.0 9T6:1201 Type1 Active DFGin 6.5381 14.4891 BLAminus -115.63, -164.58 40.59, 91.02 -103.17, 27.63 288.93, 89.27 -64.3, -31.13 in-in in 8.2901 Saltbr-in 3.264 HRD-in -73.79, -50.75 76.22, -8.05 in-in-in SNCiii in-in ActLoopNT-in 2.6624 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -60.45, 121.7 APE9-dihe-in -116.64, 165.17 APE8-dihe-in -82.47, 75.26 APE8-rot-na 26.67 APE67-dihe-in -77.47, -9.05 -66.38, -30.21 APE12-dist-na 11.3039 APE11-dist-na 10.8972 APE10-dist-na 12.893 APE9-dist-in 7.8569 K943A,K945A PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.37 0.211 0.262 A 299.0 283.0 5 31 31 0 [[545, 807], [849, 1125]] 2.0 6aaj Homo sapiens TYR_JAK2-2_HUMAN TYR 1.1e-86 296.3 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6AAJB O60674 843 1131 1132.0 9T6:1201 Type1 Active DFGin 6.5453 14.3954 BLAminus -118.96, -159.53 45.76, 82.33 -100.65, 20.72 287.12, 93.43 -66.06, -21.73 in-in in 8.5436 Saltbr-in 2.8436 HRD-in -65.44, -45.07 71.55, -13.22 in-in-in SNCiii in-in ActLoopNT-in 2.8819 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -115.56, 105.36 APE9-dihe-in -102.08, 153.39 APE8-dihe-in -76.19, 74.45 APE8-rot-na 31.79 APE67-dihe-in -76.6, 0.02 -66.92, -30.87 APE12-dist-na 999.0 APE11-dist-na 12.1768 APE10-dist-na 12.8016 APE9-dist-in 7.8139 K943A,K945A PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.37 0.211 0.262 B 299.0 274.0 15 31 29 2 [[545, 807], [849, 1125]] 2.0 6aaj Homo sapiens TYR_JAK2-2_HUMAN TYR 1.1e-86 296.3 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6AAJ — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name