PDB: 6AAJ — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6AAJA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR JAK2-2 JAK2_HUMAN 6AAJA 2.37 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9T6 Type1 843 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6AAJB 2.37 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9T6 Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2

PDB: 6AAJ — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6AAJA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR JAK2-2 JAK2_HUMAN 6AAJA 2.37 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9T6 Type1 843 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 6AAJB 2.37 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9T6 Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2 Homo sapiens

PDB: 6AAJ — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism