PDB: 5W86 — TYR JAK3_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 5W86C
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN 5W86A P52333 814 1098 1124.0 9YV:4000 Type1 Inactive DFGin 6.508 14.2333 BLAminus -130.78, -178.04 55.33, 86.29 -99.45, 24.99 285.64, 80.91 -59.45, -36.09 in-in in 8.3613 Saltbr-in 2.7197 HRD-in -61.74, -49.91 79.02, -19.05 in-in-out SNCiio in-out ActLoopNT-in 2.8338 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -62.63 APE8-dihe-in -73.09, 69.06 APE8-rot-na 28.5 APE67-dihe-in -76.22, -6.14 -68.16, -24.91 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.3257 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.61 0.211 0.264 A 287.0 271.0 14 31 26 5 [[521, 779], [822, 1097]] 2.0 5w86 TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86B P52333 816 1098 1124.0 9YV:4000 Type1 None DFGin 6.5719 14.1258 BLAminus -130.89, -177.7 55.33, 86.59 -98.74, 23.53 285.65, 80.73 -58.36, -36.34 in-in in 8.1755 Saltbr-in 2.7815 HRD-in -61.09, -43.56 75.39, -22.05 in-in-none SNCiin in-none ActLoopNT-in 2.8266 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-in -98.06, 144.28 APE8-rot-na 28.22 APE67-dihe-in -84.46, -5.87 -122.29, -17.07 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7561 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.61 0.211 0.264 B 287.0 269.0 14 31 26 5 [[521, 779], [822, 1097]] 2.0 5w86 TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86C P52333 814 1099 1124.0 9YV:4000 Type1 None DFGin 6.5069 14.1113 BLAminus -131.5, -178.51 55.57, 86.1 -97.59, 23.31 285.7, 80.13 -57.67, -36.43 in-in in 8.1655 Saltbr-in 2.9403 HRD-in -62.63, -48.44 77.31, -20.33 in-in-none SNCiin in-none ActLoopNT-in 2.8223 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -67.29 APE8-rot-na 15.79 APE67-dihe-in -70.13, -18.29 -58.03, -20.5 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.61 0.211 0.264 C 287.0 275.0 11 31 25 6 [[521, 779], [822, 1097]] 2.0 5w86 TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86D P52333 814 1099 1124.0 9YV:4000 Type1 Inactive DFGin 6.5614 14.2551 BLAminus -130.88, -178.77 56.18, 85.97 -99.02, 25.19 285.73, 80.24 -59.91, -34.36 in-in in 8.1827 Saltbr-in 2.7569 HRD-in -62.59, -49.55 78.85, -19.41 in-in-out SNCiio in-out ActLoopNT-in 2.814 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -64.08 APE8-dihe-in -73.59, 57.74 APE8-rot-na 27.09 APE67-dihe-in -73.08, -10.82 -59.31, -28.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.2414 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.61 0.211 0.264 D 287.0 274.0 12 31 26 5 [[521, 779], [822, 1097]] 2.0 5w86 TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

PDB: 5W86 — TYR JAK3_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 5W86C
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN 5W86A P52333 814 1098 1124.0 9YV:4000 Type1 Inactive DFGin 6.508 14.2333 BLAminus -130.78, -178.04 55.33, 86.29 -99.45, 24.99 285.64, 80.91 -59.45, -36.09 in-in in 8.3613 Saltbr-in 2.7197 HRD-in -61.74, -49.91 79.02, -19.05 in-in-out SNCiio in-out ActLoopNT-in 2.8338 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -62.63 APE8-dihe-in -73.09, 69.06 APE8-rot-na 28.5 APE67-dihe-in -76.22, -6.14 -68.16, -24.91 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.3257 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.61 0.211 0.264 A 287.0 271.0 14 31 26 5 [[521, 779], [822, 1097]] 2.0 5w86 Homo sapiens TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86B P52333 816 1098 1124.0 9YV:4000 Type1 None DFGin 6.5719 14.1258 BLAminus -130.89, -177.7 55.33, 86.59 -98.74, 23.53 285.65, 80.73 -58.36, -36.34 in-in in 8.1755 Saltbr-in 2.7815 HRD-in -61.09, -43.56 75.39, -22.05 in-in-none SNCiin in-none ActLoopNT-in 2.8266 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-in -98.06, 144.28 APE8-rot-na 28.22 APE67-dihe-in -84.46, -5.87 -122.29, -17.07 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7561 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.61 0.211 0.264 B 287.0 269.0 14 31 26 5 [[521, 779], [822, 1097]] 2.0 5w86 Homo sapiens TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86C P52333 814 1099 1124.0 9YV:4000 Type1 None DFGin 6.5069 14.1113 BLAminus -131.5, -178.51 55.57, 86.1 -97.59, 23.31 285.7, 80.13 -57.67, -36.43 in-in in 8.1655 Saltbr-in 2.9403 HRD-in -62.63, -48.44 77.31, -20.33 in-in-none SNCiin in-none ActLoopNT-in 2.8223 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -67.29 APE8-rot-na 15.79 APE67-dihe-in -70.13, -18.29 -58.03, -20.5 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.61 0.211 0.264 C 287.0 275.0 11 31 25 6 [[521, 779], [822, 1097]] 2.0 5w86 Homo sapiens TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86D P52333 814 1099 1124.0 9YV:4000 Type1 Inactive DFGin 6.5614 14.2551 BLAminus -130.88, -178.77 56.18, 85.97 -99.02, 25.19 285.73, 80.24 -59.91, -34.36 in-in in 8.1827 Saltbr-in 2.7569 HRD-in -62.59, -49.55 78.85, -19.41 in-in-out SNCiio in-out ActLoopNT-in 2.814 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -64.08 APE8-dihe-in -73.59, 57.74 APE8-rot-na 27.09 APE67-dihe-in -73.08, -10.82 -59.31, -28.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.2414 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.61 0.211 0.264 D 287.0 274.0 12 31 26 5 [[521, 779], [822, 1097]] 2.0 5w86 Homo sapiens TYR_JAK3-2_HUMAN TYR 1.9e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

PDB: 5W86 — TYR JAK3_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name