PDB: 4LRM — TYR EGFR_HUMAN

Total number of chains: 5
Active chains: 5
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 4LRMA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4LRMA P00533 696 999 1210.0 YUN:61101 Type1 Active DFGin 4.93 14.141 BLAminus -158.6, -179.81 59.5, 67.69 -73.3, -10.6 304.95, 80.93 -43.1, -43.98 in-in in 8.525 Saltbr-in 2.25 HRD-in -63.46, -47.09 80.09, -2.56 in-in-in SNCiii in-in ActLoopNT-in 3.48 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -123.95, 131.0 APE9-dihe-in -142.36, 158.24 APE8-dihe-in -79.28, 92.61 APE8-rot-na 26.9 APE67-dihe-in -59.89, -28.15 -57.58, -49.17 APE12-dist-na 9.439 APE11-dist-na 11.082 APE10-dist-na 9.688 APE9-dist-in 7.132 None None None XRAY 3.526 0.227 0.264 A 334 304 0 0 0 0 [[712, 970]] 1.0 4lrm TYR_EGFR_HUMAN TYR 1.7e-85 292.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMB P00533 695 984 1210.0 YUN:61101 Type1 Active DFGin 5.532 14.623 BLAminus -142.14, -169.88 61.38, 66.02 -84.65, 8.68 301.37, 83.75 -51.1, -43.11 in-in in 8.174 Saltbr-in 2.299 HRD-in -63.69, -44.58 74.58, 1.29 in-in-in SNCiii in-in ActLoopNT-in 3.42 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -94.16, 130.29 APE9-dihe-in -170.64, 141.47 APE8-dihe-in -73.49, 101.45 APE8-rot-na 22.26 APE67-dihe-in -63.2, -7.11 -64.86, -46.08 APE12-dist-na 10.44 APE11-dist-na 11.621 APE10-dist-na 9.395 APE9-dist-in 6.862 None None None XRAY 3.526 0.227 0.264 B 334 290 0 0 0 0 [[712, 970]] 1.0 4lrm TYR_EGFR_HUMAN TYR 1.7e-85 292.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMC P00533 694 983 1210.0 YUN:61101 Type1 Active DFGin 5.508 14.779 BLAminus -160.48, -176.43 59.92, 67.08 -79.93, -1.69 283.78, 100.07 -59.01, -39.57 in-in in 8.9 Saltbr-in 3.071 HRD-in -63.5, -47.73 78.4, -4.25 in-in-in SNCiii in-in ActLoopNT-in 3.24 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -126.48, 145.03 APE9-dihe-in -149.11, 167.52 APE8-dihe-in -81.81, 92.2 APE8-rot-na 26.63 APE67-dihe-in -60.5, -24.4 -61.07, -44.78 APE12-dist-na 10.454 APE11-dist-na 12.259 APE10-dist-na 11.083 APE9-dist-in 7.237 None None None XRAY 3.526 0.227 0.264 C 334 290 0 0 0 0 [[712, 970]] 1.0 4lrm TYR_EGFR_HUMAN TYR 1.7e-85 292.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMD P00533 696 981 1210.0 YUN:61101 Type1 Active DFGin 5.712 15.251 BLAminus -148.37, -162.17 52.48, 44.96 -64.79, -16.2 243.39, 79.15 -40.26, -53.82 in-in in 8.723 Saltbr-in 3.075 HRD-in -62.93, -45.84 76.67, -2.7 in-in-in SNCiii in-in ActLoopNT-in 3.103 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -99.87, 124.7 APE9-dihe-in -148.33, 129.49 APE8-dihe-in -84.5, 68.54 APE8-rot-na 31.24 APE67-dihe-in -68.57, -19.39 -40.54, -45.59 APE12-dist-na 9.638 APE11-dist-na 11.365 APE10-dist-na 8.404 APE9-dist-in 7.285 None None None XRAY 3.526 0.227 0.264 D 334 286 0 0 0 0 [[712, 970]] 1.0 4lrm TYR_EGFR_HUMAN TYR 1.7e-85 292.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRME P00533 697 983 1210.0 YUN:61101 Type1 Active DFGin 5.122 15.128 BLAminus -149.12, 177.76 56.26, 51.42 -60.22, -36.0 278.23, 76.29 -54.0, 140.36 in-in in 8.548 Saltbr-in 2.983 HRD-in -64.42, -45.57 82.92, -8.54 in-in-in SNCiii in-in ActLoopNT-in 3.08 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -59.92, 140.02 APE9-dihe-in -130.51, 156.61 APE8-dihe-in -89.68, 108.31 APE8-rot-na 37.48 APE67-dihe-in -56.1, -15.47 -64.45, -45.1 APE12-dist-na 11.529 APE11-dist-na 9.116 APE10-dist-na 10.778 APE9-dist-in 6.782 None None None XRAY 3.526 0.227 0.264 E 334 287 0 0 0 0 [[712, 970]] 1.0 4lrm TYR_EGFR_HUMAN TYR 1.7e-85 292.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 4LRM — TYR EGFR_HUMAN

Total number of chains: 5
Active chains: 5
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 4LRMA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4LRMA P00533 696 999 1210.0 YUN:61101 Type1 Active DFGin 4.93 14.141 BLAminus -158.6, -179.81 59.5, 67.69 -73.3, -10.6 304.95, 80.93 -43.1, -43.98 in-in in 8.525 Saltbr-in 2.25 HRD-in -63.46, -47.09 80.09, -2.56 in-in-in SNCiii in-in ActLoopNT-in 3.48 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -123.95, 131.0 APE9-dihe-in -142.36, 158.24 APE8-dihe-in -79.28, 92.61 APE8-rot-na 26.9 APE67-dihe-in -59.89, -28.15 -57.58, -49.17 APE12-dist-na 9.439 APE11-dist-na 11.082 APE10-dist-na 9.688 APE9-dist-in 7.132 None None None XRAY 3.526 0.227 0.264 A 334 304 0 0 0 0 [[712, 970]] 1.0 4lrm Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMB P00533 695 984 1210.0 YUN:61101 Type1 Active DFGin 5.532 14.623 BLAminus -142.14, -169.88 61.38, 66.02 -84.65, 8.68 301.37, 83.75 -51.1, -43.11 in-in in 8.174 Saltbr-in 2.299 HRD-in -63.69, -44.58 74.58, 1.29 in-in-in SNCiii in-in ActLoopNT-in 3.42 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -94.16, 130.29 APE9-dihe-in -170.64, 141.47 APE8-dihe-in -73.49, 101.45 APE8-rot-na 22.26 APE67-dihe-in -63.2, -7.11 -64.86, -46.08 APE12-dist-na 10.44 APE11-dist-na 11.621 APE10-dist-na 9.395 APE9-dist-in 6.862 None None None XRAY 3.526 0.227 0.264 B 334 290 0 0 0 0 [[712, 970]] 1.0 4lrm Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMC P00533 694 983 1210.0 YUN:61101 Type1 Active DFGin 5.508 14.779 BLAminus -160.48, -176.43 59.92, 67.08 -79.93, -1.69 283.78, 100.07 -59.01, -39.57 in-in in 8.9 Saltbr-in 3.071 HRD-in -63.5, -47.73 78.4, -4.25 in-in-in SNCiii in-in ActLoopNT-in 3.24 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -126.48, 145.03 APE9-dihe-in -149.11, 167.52 APE8-dihe-in -81.81, 92.2 APE8-rot-na 26.63 APE67-dihe-in -60.5, -24.4 -61.07, -44.78 APE12-dist-na 10.454 APE11-dist-na 12.259 APE10-dist-na 11.083 APE9-dist-in 7.237 None None None XRAY 3.526 0.227 0.264 C 334 290 0 0 0 0 [[712, 970]] 1.0 4lrm Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMD P00533 696 981 1210.0 YUN:61101 Type1 Active DFGin 5.712 15.251 BLAminus -148.37, -162.17 52.48, 44.96 -64.79, -16.2 243.39, 79.15 -40.26, -53.82 in-in in 8.723 Saltbr-in 3.075 HRD-in -62.93, -45.84 76.67, -2.7 in-in-in SNCiii in-in ActLoopNT-in 3.103 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -99.87, 124.7 APE9-dihe-in -148.33, 129.49 APE8-dihe-in -84.5, 68.54 APE8-rot-na 31.24 APE67-dihe-in -68.57, -19.39 -40.54, -45.59 APE12-dist-na 9.638 APE11-dist-na 11.365 APE10-dist-na 8.404 APE9-dist-in 7.285 None None None XRAY 3.526 0.227 0.264 D 334 286 0 0 0 0 [[712, 970]] 1.0 4lrm Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRME P00533 697 983 1210.0 YUN:61101 Type1 Active DFGin 5.122 15.128 BLAminus -149.12, 177.76 56.26, 51.42 -60.22, -36.0 278.23, 76.29 -54.0, 140.36 in-in in 8.548 Saltbr-in 2.983 HRD-in -64.42, -45.57 82.92, -8.54 in-in-in SNCiii in-in ActLoopNT-in 3.08 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -59.92, 140.02 APE9-dihe-in -130.51, 156.61 APE8-dihe-in -89.68, 108.31 APE8-rot-na 37.48 APE67-dihe-in -56.1, -15.47 -64.45, -45.1 APE12-dist-na 11.529 APE11-dist-na 9.116 APE10-dist-na 10.778 APE9-dist-in 6.782 None None None XRAY 3.526 0.227 0.264 E 334 287 0 0 0 0 [[712, 970]] 1.0 4lrm Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 4LRM — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name