PDB: 4J99 — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4J99B
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 4J99A P21802 466 764 821.0 ACP:802 ATPlike Inactive DFGin 6.715 14.14 BLAminus -130.96, -174.69 58.83, 77.45 -92.73, 19.29 291.78, 87.39 -60.03, -34.11 in-in in 7.61 Saltbr-in 2.845 HRD-in -78.19, -48.52 73.01, -4.76 in-in-out SNCiio in-out ActLoopNT-in 2.861 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -115.36, 29.03 APE9-dihe-in -109.75, 138.54 APE8-dihe-in -57.3, 116.33 APE8-rot-na 330.48 APE67-dihe-in -70.7, -10.42 -57.47, -40.52 APE12-dist-na 15.04 APE11-dist-na 11.232 APE10-dist-na 7.972 APE9-dist-in 5.13 C491A,K659T None None XRAY 1.847 0.206 0.24 A 324 280 19 0 0 4 [[481, 759]] 1.0 4j99 TYR_FGFR2_HUMAN TYR 2e-104 354.4 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99B P21802 467 764 821.0 ACP:802 ATPlike Inactive DFGin 6.666 14.188 BLAminus -133.21, -176.0 58.56, 76.97 -94.04, 15.78 292.83, 99.53 -58.91, -32.83 in-in in 7.584 Saltbr-in 2.616 HRD-in -76.65, -48.86 73.31, -6.92 in-in-out SNCiio in-out ActLoopNT-in 2.9 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -118.89, 30.62 APE9-dihe-in -108.84, 137.25 APE8-dihe-in -57.12, 118.19 APE8-rot-na 330.19 APE67-dihe-in -70.1, -10.12 -57.01, -39.76 APE12-dist-na 14.148 APE11-dist-na 11.074 APE10-dist-na 8.007 APE9-dist-in 5.18 C491A,K659T None None XRAY 1.847 0.206 0.24 B 324 291 7 0 0 0 [[481, 759]] 1.0 4j99 TYR_FGFR2_HUMAN TYR 2e-104 354.4 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99C P21802 467 764 821.0 ACP:802 ATPlike Inactive DFGin 6.835 14.168 BLAminus -131.87, -175.54 59.17, 75.71 -91.42, 19.92 291.67, 85.71 -59.92, -32.59 in-in in 7.628 Saltbr-in 2.913 HRD-in -76.88, -47.72 74.23, -7.36 in-in-out SNCiio in-out ActLoopNT-in 2.894 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -117.66, 30.6 APE9-dihe-in -110.19, 138.06 APE8-dihe-in -55.44, 118.46 APE8-rot-na 330.51 APE67-dihe-in -70.73, -10.29 -57.12, -38.65 APE12-dist-na 14.121 APE11-dist-na 10.954 APE10-dist-na 8.05 APE9-dist-in 5.362 C491A,K659T None None XRAY 1.847 0.206 0.24 C 324 291 7 0 0 0 [[481, 759]] 1.0 4j99 TYR_FGFR2_HUMAN TYR 2e-104 354.4 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99D P21802 465 764 821.0 ACP:802 ATPlike Inactive DFGin 6.593 14.159 BLAminus -133.66, -174.57 58.72, 78.56 -92.61, 20.44 290.96, 82.99 -59.4, -33.38 in-in in 7.631 Saltbr-in 2.639 HRD-in -78.38, -50.11 73.68, -6.22 in-in-out SNCiio in-out ActLoopNT-in 2.893 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -117.76, 31.03 APE9-dihe-in -108.34, 137.61 APE8-dihe-in -55.35, 118.06 APE8-rot-na 330.85 APE67-dihe-in -71.9, -11.56 -55.67, -38.95 APE12-dist-na 999.0 APE11-dist-na 11.135 APE10-dist-na 7.859 APE9-dist-in 4.992 C491A,K659T None None XRAY 1.847 0.206 0.24 D 324 281 19 0 0 3 [[481, 759]] 1.0 4j99 TYR_FGFR2_HUMAN TYR 2e-104 354.4 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 4J99 — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4J99B
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 4J99A P21802 466 764 821.0 ACP:802 ATPlike Inactive DFGin 6.715 14.14 BLAminus -130.96, -174.69 58.83, 77.45 -92.73, 19.29 291.78, 87.39 -60.03, -34.11 in-in in 7.61 Saltbr-in 2.845 HRD-in -78.19, -48.52 73.01, -4.76 in-in-out SNCiio in-out ActLoopNT-in 2.861 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -115.36, 29.03 APE9-dihe-in -109.75, 138.54 APE8-dihe-in -57.3, 116.33 APE8-rot-na 330.48 APE67-dihe-in -70.7, -10.42 -57.47, -40.52 APE12-dist-na 15.04 APE11-dist-na 11.232 APE10-dist-na 7.972 APE9-dist-in 5.13 C491A,K659T None None XRAY 1.847 0.206 0.24 A 324 280 19 0 0 4 [[481, 759]] 1.0 4j99 Homo sapiens TYR_FGFR2_HUMAN TYR 2e-104 354.4 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99B P21802 467 764 821.0 ACP:802 ATPlike Inactive DFGin 6.666 14.188 BLAminus -133.21, -176.0 58.56, 76.97 -94.04, 15.78 292.83, 99.53 -58.91, -32.83 in-in in 7.584 Saltbr-in 2.616 HRD-in -76.65, -48.86 73.31, -6.92 in-in-out SNCiio in-out ActLoopNT-in 2.9 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -118.89, 30.62 APE9-dihe-in -108.84, 137.25 APE8-dihe-in -57.12, 118.19 APE8-rot-na 330.19 APE67-dihe-in -70.1, -10.12 -57.01, -39.76 APE12-dist-na 14.148 APE11-dist-na 11.074 APE10-dist-na 8.007 APE9-dist-in 5.18 C491A,K659T None None XRAY 1.847 0.206 0.24 B 324 291 7 0 0 0 [[481, 759]] 1.0 4j99 Homo sapiens TYR_FGFR2_HUMAN TYR 2e-104 354.4 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99C P21802 467 764 821.0 ACP:802 ATPlike Inactive DFGin 6.835 14.168 BLAminus -131.87, -175.54 59.17, 75.71 -91.42, 19.92 291.67, 85.71 -59.92, -32.59 in-in in 7.628 Saltbr-in 2.913 HRD-in -76.88, -47.72 74.23, -7.36 in-in-out SNCiio in-out ActLoopNT-in 2.894 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -117.66, 30.6 APE9-dihe-in -110.19, 138.06 APE8-dihe-in -55.44, 118.46 APE8-rot-na 330.51 APE67-dihe-in -70.73, -10.29 -57.12, -38.65 APE12-dist-na 14.121 APE11-dist-na 10.954 APE10-dist-na 8.05 APE9-dist-in 5.362 C491A,K659T None None XRAY 1.847 0.206 0.24 C 324 291 7 0 0 0 [[481, 759]] 1.0 4j99 Homo sapiens TYR_FGFR2_HUMAN TYR 2e-104 354.4 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99D P21802 465 764 821.0 ACP:802 ATPlike Inactive DFGin 6.593 14.159 BLAminus -133.66, -174.57 58.72, 78.56 -92.61, 20.44 290.96, 82.99 -59.4, -33.38 in-in in 7.631 Saltbr-in 2.639 HRD-in -78.38, -50.11 73.68, -6.22 in-in-out SNCiio in-out ActLoopNT-in 2.893 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -117.76, 31.03 APE9-dihe-in -108.34, 137.61 APE8-dihe-in -55.35, 118.06 APE8-rot-na 330.85 APE67-dihe-in -71.9, -11.56 -55.67, -38.95 APE12-dist-na 999.0 APE11-dist-na 11.135 APE10-dist-na 7.859 APE9-dist-in 4.992 C491A,K659T None None XRAY 1.847 0.206 0.24 D 324 281 19 0 0 3 [[481, 759]] 1.0 4j99 Homo sapiens TYR_FGFR2_HUMAN TYR 2e-104 354.4 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 4J99 — TYR FGFR2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name