PDB: 4J97 — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4J97B
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 4J97A P21802 468 764 821.0 ACP:801 ATPlike Inactive DFGin 6.55 14.123 BLAminus -139.14, -173.61 59.78, 71.54 -95.85, 23.3 290.64, 88.77 -67.56, -16.73 in-in in 7.316 Saltbr-in 3.004 HRD-in -83.97, -47.07 72.51, -7.44 in-in-out SNCiio in-out ActLoopNT-in 2.877 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -104.39, 21.13 APE9-dihe-in -97.79, 130.15 APE8-dihe-in -58.11, 126.83 APE8-rot-na 332.95 APE67-dihe-in -66.85, -7.34 -61.56, -42.87 APE12-dist-na 15.336 APE11-dist-na 10.692 APE10-dist-na 7.744 APE9-dist-in 4.882 C491A,K659E None None XRAY 2.548 0.202 0.257 A 324 282 15 0 0 0 [[481, 759]] 1.0 4j97 TYR_FGFR2_HUMAN TYR 2.8e-104 353.9 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97B P21802 468 764 821.0 ACP:801 ATPlike Inactive DFGin 6.619 14.161 BLAminus -137.2, -170.97 56.98, 77.11 -102.2, 28.96 291.71, 89.32 -70.08, -17.2 in-in in 7.432 Saltbr-in 2.683 HRD-in -92.02, -43.47 71.93, -10.83 in-in-out SNCiio in-out ActLoopNT-in 2.882 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -109.22, 28.28 APE9-dihe-in -102.89, 130.04 APE8-dihe-in -52.94, 125.61 APE8-rot-na 331.88 APE67-dihe-in -68.38, -8.99 -59.09, -43.64 APE12-dist-na 15.333 APE11-dist-na 10.637 APE10-dist-na 7.778 APE9-dist-in 4.888 C491A,K659E None None XRAY 2.548 0.202 0.257 B 324 283 14 0 0 0 [[481, 759]] 1.0 4j97 TYR_FGFR2_HUMAN TYR 2.8e-104 353.9 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97C P21802 467 764 821.0 ACP:801 ATPlike Inactive DFGin 6.645 13.946 BLAminus -135.48, -176.12 59.98, 78.76 -103.0, 29.61 294.18, 85.28 -73.23, -9.75 in-in in 7.37 Saltbr-in 2.772 HRD-in -84.13, -44.14 69.93, -6.04 in-in-out SNCiio in-out ActLoopNT-in 2.837 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -106.47, 19.13 APE9-dihe-in -91.95, 123.86 APE8-dihe-in -53.96, 120.55 APE8-rot-na 330.23 APE67-dihe-in -67.12, -15.11 -56.46, -44.57 APE12-dist-na 15.284 APE11-dist-na 10.828 APE10-dist-na 7.639 APE9-dist-in 4.85 C491A,K659E None None XRAY 2.548 0.202 0.257 C 324 283 15 0 0 0 [[481, 759]] 1.0 4j97 TYR_FGFR2_HUMAN TYR 2.8e-104 353.9 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97D P21802 466 764 821.0 ACP:801 ATPlike Inactive DFGin 6.6 13.952 BLAminus -140.55, -174.15 59.58, 71.6 -94.76, 28.97 293.72, 82.5 -71.76, -12.96 in-in in 7.326 Saltbr-in 3.288 HRD-in -86.64, -45.82 71.0, -4.65 in-in-out SNCiio in-out ActLoopNT-in 2.976 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -106.43, 15.17 APE9-dihe-in -92.91, 126.7 APE8-dihe-in -55.77, 123.75 APE8-rot-na 332.18 APE67-dihe-in -67.8, -5.5 -58.98, -44.55 APE12-dist-na 15.175 APE11-dist-na 10.81 APE10-dist-na 7.653 APE9-dist-in 4.774 C491A,K659E None None XRAY 2.548 0.202 0.257 D 324 285 14 0 0 0 [[481, 759]] 1.0 4j97 TYR_FGFR2_HUMAN TYR 2.8e-104 353.9 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 4J97 — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4J97B
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 4J97A P21802 468 764 821.0 ACP:801 ATPlike Inactive DFGin 6.55 14.123 BLAminus -139.14, -173.61 59.78, 71.54 -95.85, 23.3 290.64, 88.77 -67.56, -16.73 in-in in 7.316 Saltbr-in 3.004 HRD-in -83.97, -47.07 72.51, -7.44 in-in-out SNCiio in-out ActLoopNT-in 2.877 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -104.39, 21.13 APE9-dihe-in -97.79, 130.15 APE8-dihe-in -58.11, 126.83 APE8-rot-na 332.95 APE67-dihe-in -66.85, -7.34 -61.56, -42.87 APE12-dist-na 15.336 APE11-dist-na 10.692 APE10-dist-na 7.744 APE9-dist-in 4.882 C491A,K659E None None XRAY 2.548 0.202 0.257 A 324 282 15 0 0 0 [[481, 759]] 1.0 4j97 Homo sapiens TYR_FGFR2_HUMAN TYR 2.8e-104 353.9 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97B P21802 468 764 821.0 ACP:801 ATPlike Inactive DFGin 6.619 14.161 BLAminus -137.2, -170.97 56.98, 77.11 -102.2, 28.96 291.71, 89.32 -70.08, -17.2 in-in in 7.432 Saltbr-in 2.683 HRD-in -92.02, -43.47 71.93, -10.83 in-in-out SNCiio in-out ActLoopNT-in 2.882 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -109.22, 28.28 APE9-dihe-in -102.89, 130.04 APE8-dihe-in -52.94, 125.61 APE8-rot-na 331.88 APE67-dihe-in -68.38, -8.99 -59.09, -43.64 APE12-dist-na 15.333 APE11-dist-na 10.637 APE10-dist-na 7.778 APE9-dist-in 4.888 C491A,K659E None None XRAY 2.548 0.202 0.257 B 324 283 14 0 0 0 [[481, 759]] 1.0 4j97 Homo sapiens TYR_FGFR2_HUMAN TYR 2.8e-104 353.9 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97C P21802 467 764 821.0 ACP:801 ATPlike Inactive DFGin 6.645 13.946 BLAminus -135.48, -176.12 59.98, 78.76 -103.0, 29.61 294.18, 85.28 -73.23, -9.75 in-in in 7.37 Saltbr-in 2.772 HRD-in -84.13, -44.14 69.93, -6.04 in-in-out SNCiio in-out ActLoopNT-in 2.837 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -106.47, 19.13 APE9-dihe-in -91.95, 123.86 APE8-dihe-in -53.96, 120.55 APE8-rot-na 330.23 APE67-dihe-in -67.12, -15.11 -56.46, -44.57 APE12-dist-na 15.284 APE11-dist-na 10.828 APE10-dist-na 7.639 APE9-dist-in 4.85 C491A,K659E None None XRAY 2.548 0.202 0.257 C 324 283 15 0 0 0 [[481, 759]] 1.0 4j97 Homo sapiens TYR_FGFR2_HUMAN TYR 2.8e-104 353.9 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97D P21802 466 764 821.0 ACP:801 ATPlike Inactive DFGin 6.6 13.952 BLAminus -140.55, -174.15 59.58, 71.6 -94.76, 28.97 293.72, 82.5 -71.76, -12.96 in-in in 7.326 Saltbr-in 3.288 HRD-in -86.64, -45.82 71.0, -4.65 in-in-out SNCiio in-out ActLoopNT-in 2.976 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -106.43, 15.17 APE9-dihe-in -92.91, 126.7 APE8-dihe-in -55.77, 123.75 APE8-rot-na 332.18 APE67-dihe-in -67.8, -5.5 -58.98, -44.55 APE12-dist-na 15.175 APE11-dist-na 10.81 APE10-dist-na 7.653 APE9-dist-in 4.774 C491A,K659E None None XRAY 2.548 0.202 0.257 D 324 285 14 0 0 0 [[481, 759]] 1.0 4j97 Homo sapiens TYR_FGFR2_HUMAN TYR 2.8e-104 353.9 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 4J97 — TYR FGFR2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name