PDB: 4J95 — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4J95B
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 4J95A P21802 467 764 821.0 ACP:801 ATPlike Inactive DFGin 6.691 14.058 BLAminus -131.56, -174.19 63.25, 76.63 -98.25, 22.24 292.31, 85.68 -64.6, -23.3 in-in in 7.752 Saltbr-in 2.811 HRD-in -79.93, -52.54 74.87, -4.09 in-in-out SNCiio in-out ActLoopNT-in 2.992 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -111.79, 21.67 APE9-dihe-in -99.53, 131.21 APE8-dihe-in -54.93, 120.24 APE8-rot-na 331.68 APE67-dihe-in -73.86, -8.05 -61.39, -39.09 APE12-dist-na 14.773 APE11-dist-na 10.953 APE10-dist-na 7.48 APE9-dist-in 4.867 C491A,K659N None None XRAY 2.377 0.214 0.255 A 324 279 19 0 0 4 [[481, 759]] 1.0 4j95 TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95B P21802 468 764 821.0 ACP:801 ATPlike Inactive DFGin 6.677 14.378 BLAminus -131.79, -176.38 62.78, 77.42 -96.59, 21.6 290.19, 86.46 -65.99, -23.31 in-in in 7.797 Saltbr-in 2.903 HRD-in -80.06, -52.15 74.05, -5.91 in-in-out SNCiio in-out ActLoopNT-in 2.897 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -111.95, 20.73 APE9-dihe-in -101.19, 131.88 APE8-dihe-in -53.9, 121.25 APE8-rot-na 331.03 APE67-dihe-in -73.96, -6.54 -59.67, -39.95 APE12-dist-na 14.977 APE11-dist-na 11.021 APE10-dist-na 7.709 APE9-dist-in 4.856 C491A,K659N None None XRAY 2.377 0.214 0.255 B 324 282 15 0 0 0 [[481, 759]] 1.0 4j95 TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95C P21802 468 764 821.0 ACP:801 ATPlike Inactive DFGin 6.762 14.317 BLAminus -132.19, -176.54 63.57, 76.14 -98.34, 23.39 290.03, 85.39 -65.87, -22.89 in-in in 7.736 Saltbr-in 2.825 HRD-in -79.64, -52.73 75.27, -7.0 in-in-out SNCiio in-out ActLoopNT-in 2.959 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -104.5, 23.85 APE9-dihe-in -97.28, 128.27 APE8-dihe-in -54.92, 121.79 APE8-rot-na 330.61 APE67-dihe-in -73.19, -7.42 -60.17, -39.19 APE12-dist-na 14.732 APE11-dist-na 10.365 APE10-dist-na 7.413 APE9-dist-in 4.906 C491A,K659N None None XRAY 2.377 0.214 0.255 C 324 281 16 0 0 0 [[481, 759]] 1.0 4j95 TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95D P21802 467 764 821.0 ACP:801 ATPlike Inactive DFGin 6.601 14.074 BLAminus -131.84, -175.28 62.91, 77.06 -96.79, 22.82 289.52, 85.1 -64.56, -22.95 in-in in 7.641 Saltbr-in 2.747 HRD-in -80.37, -53.3 74.73, -6.2 in-in-out SNCiio in-out ActLoopNT-in 3.033 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -112.03, 23.13 APE9-dihe-in -98.93, 130.46 APE8-dihe-in -52.66, 122.62 APE8-rot-na 330.72 APE67-dihe-in -75.07, -8.74 -59.5, -40.3 APE12-dist-na 999.0 APE11-dist-na 10.804 APE10-dist-na 7.616 APE9-dist-in 4.803 C491A,K659N None None XRAY 2.377 0.214 0.255 D 324 271 27 0 0 11 [[481, 759]] 1.0 4j95 TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 4J95 — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4J95B
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 4J95A P21802 467 764 821.0 ACP:801 ATPlike Inactive DFGin 6.691 14.058 BLAminus -131.56, -174.19 63.25, 76.63 -98.25, 22.24 292.31, 85.68 -64.6, -23.3 in-in in 7.752 Saltbr-in 2.811 HRD-in -79.93, -52.54 74.87, -4.09 in-in-out SNCiio in-out ActLoopNT-in 2.992 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -111.79, 21.67 APE9-dihe-in -99.53, 131.21 APE8-dihe-in -54.93, 120.24 APE8-rot-na 331.68 APE67-dihe-in -73.86, -8.05 -61.39, -39.09 APE12-dist-na 14.773 APE11-dist-na 10.953 APE10-dist-na 7.48 APE9-dist-in 4.867 C491A,K659N None None XRAY 2.377 0.214 0.255 A 324 279 19 0 0 4 [[481, 759]] 1.0 4j95 Homo sapiens TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95B P21802 468 764 821.0 ACP:801 ATPlike Inactive DFGin 6.677 14.378 BLAminus -131.79, -176.38 62.78, 77.42 -96.59, 21.6 290.19, 86.46 -65.99, -23.31 in-in in 7.797 Saltbr-in 2.903 HRD-in -80.06, -52.15 74.05, -5.91 in-in-out SNCiio in-out ActLoopNT-in 2.897 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -111.95, 20.73 APE9-dihe-in -101.19, 131.88 APE8-dihe-in -53.9, 121.25 APE8-rot-na 331.03 APE67-dihe-in -73.96, -6.54 -59.67, -39.95 APE12-dist-na 14.977 APE11-dist-na 11.021 APE10-dist-na 7.709 APE9-dist-in 4.856 C491A,K659N None None XRAY 2.377 0.214 0.255 B 324 282 15 0 0 0 [[481, 759]] 1.0 4j95 Homo sapiens TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95C P21802 468 764 821.0 ACP:801 ATPlike Inactive DFGin 6.762 14.317 BLAminus -132.19, -176.54 63.57, 76.14 -98.34, 23.39 290.03, 85.39 -65.87, -22.89 in-in in 7.736 Saltbr-in 2.825 HRD-in -79.64, -52.73 75.27, -7.0 in-in-out SNCiio in-out ActLoopNT-in 2.959 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -104.5, 23.85 APE9-dihe-in -97.28, 128.27 APE8-dihe-in -54.92, 121.79 APE8-rot-na 330.61 APE67-dihe-in -73.19, -7.42 -60.17, -39.19 APE12-dist-na 14.732 APE11-dist-na 10.365 APE10-dist-na 7.413 APE9-dist-in 4.906 C491A,K659N None None XRAY 2.377 0.214 0.255 C 324 281 16 0 0 0 [[481, 759]] 1.0 4j95 Homo sapiens TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95D P21802 467 764 821.0 ACP:801 ATPlike Inactive DFGin 6.601 14.074 BLAminus -131.84, -175.28 62.91, 77.06 -96.79, 22.82 289.52, 85.1 -64.56, -22.95 in-in in 7.641 Saltbr-in 2.747 HRD-in -80.37, -53.3 74.73, -6.2 in-in-out SNCiio in-out ActLoopNT-in 3.033 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -112.03, 23.13 APE9-dihe-in -98.93, 130.46 APE8-dihe-in -52.66, 122.62 APE8-rot-na 330.72 APE67-dihe-in -75.07, -8.74 -59.5, -40.3 APE12-dist-na 999.0 APE11-dist-na 10.804 APE10-dist-na 7.616 APE9-dist-in 4.803 C491A,K659N None None XRAY 2.377 0.214 0.255 D 324 271 27 0 0 11 [[481, 759]] 1.0 4j95 Homo sapiens TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 4J95 — TYR FGFR2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name