PDB: 4IZ7 — CMGC MK01_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4IZ7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 4IZ7A P28482 11 360 360.0 No_ligand No_ligand Inactive DFGin 6.7791 16.3853 BLAminus -132.97, -178.72 63.66, 80.29 -101.39, 20.27 283.23, 71.58 -61.04, -25.26 out-in out 10.3002 Saltbr-in 2.6775 HRD-in -78.11, -51.56 79.12, -6.4 in-in-out SNCiio in-out ActLoopNT-in 2.7898 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iiio APE10-dihe-na -85.94, 135.52 APE9-dihe-na -28.41, -102.11 APE8-dihe-in -66.17, 105.49 APE8-rot-in 328.49 APE67-dihe-in -65.55, -19.28 -51.85, -44.19 APE12-dist-in 12.3652 APE11-dist-in 11.8165 APE10-dist-in 5.9776 APE9-dist-out 6.7345 None None None XRAY 1.8 0.187 0.222 A 356.0 344.0 6 31 25 6 [[25, 313]] 1.0 4iz7 CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZ7C P28482 11 359 360.0 No_ligand No_ligand Inactive DFGin 6.8265 16.3954 BLAminus -132.72, -179.02 62.3, 79.44 -102.34, 20.3 285.22, 75.68 -54.93, -29.16 in-in in 9.9694 Saltbr-in 2.6399 HRD-in -74.05, -47.12 72.94, -4.3 in-in-out SNCiio in-out ActLoopNT-in 2.8605 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioo APE10-dihe-na -129.15, 147.4 APE9-dihe-na -70.28, -33.83 APE8-dihe-in -115.27, 111.37 APE8-rot-in 304.75 APE67-dihe-in -74.12, -3.61 -106.1, -7.47 APE12-dist-out 6.7811 APE11-dist-in 10.8335 APE10-dist-out 8.9253 APE9-dist-out 11.3512 None None None XRAY 1.8 0.187 0.222 C 356.0 340.0 9 31 22 9 [[25, 313]] 1.0 4iz7 CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

PDB: 4IZ7 — CMGC MK01_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4IZ7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 4IZ7A P28482 11 360 360.0 No_ligand No_ligand Inactive DFGin 6.7791 16.3853 BLAminus -132.97, -178.72 63.66, 80.29 -101.39, 20.27 283.23, 71.58 -61.04, -25.26 out-in out 10.3002 Saltbr-in 2.6775 HRD-in -78.11, -51.56 79.12, -6.4 in-in-out SNCiio in-out ActLoopNT-in 2.7898 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iiio APE10-dihe-na -85.94, 135.52 APE9-dihe-na -28.41, -102.11 APE8-dihe-in -66.17, 105.49 APE8-rot-in 328.49 APE67-dihe-in -65.55, -19.28 -51.85, -44.19 APE12-dist-in 12.3652 APE11-dist-in 11.8165 APE10-dist-in 5.9776 APE9-dist-out 6.7345 None None None XRAY 1.8 0.187 0.222 A 356.0 344.0 6 31 25 6 [[25, 313]] 1.0 4iz7 Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZ7C P28482 11 359 360.0 No_ligand No_ligand Inactive DFGin 6.8265 16.3954 BLAminus -132.72, -179.02 62.3, 79.44 -102.34, 20.3 285.22, 75.68 -54.93, -29.16 in-in in 9.9694 Saltbr-in 2.6399 HRD-in -74.05, -47.12 72.94, -4.3 in-in-out SNCiio in-out ActLoopNT-in 2.8605 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioo APE10-dihe-na -129.15, 147.4 APE9-dihe-na -70.28, -33.83 APE8-dihe-in -115.27, 111.37 APE8-rot-in 304.75 APE67-dihe-in -74.12, -3.61 -106.1, -7.47 APE12-dist-out 6.7811 APE11-dist-in 10.8335 APE10-dist-out 8.9253 APE9-dist-out 11.3512 None None None XRAY 1.8 0.187 0.222 C 356.0 340.0 9 31 22 9 [[25, 313]] 1.0 4iz7 Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

PDB: 4IZ7 — CMGC MK01_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name