PDB: 4IMY — CMGC CDK9_HUMAN

Total number of chains: 3
Active chains: 3
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4IMYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK9 CDK9_HUMAN 4IMYC P50750 8 330 372.0 AMP:401 ATPlike Active DFGin 6.7892 15.1227 BLAminus -140.61, 175.84 60.41, 77.79 -97.02, 19.01 284.69, 80.72 -68.98, -8.54 in-in in 9.2316 Saltbr-in 2.8334 HRD-in -67.68, -50.97 65.16, 13.16 in-in-in SNCiii in-in ActLoopNT-in 2.9277 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.81, 161.81 APE9-dihe-na 73.71, 135.92 APE8-dihe-in -53.34, 141.57 APE8-rot-in 294.85 APE67-dihe-in -61.16, -25.06 -47.9, -50.46 APE12-dist-in 13.386 APE11-dist-in 11.4309 APE10-dist-in 7.0061 APE9-dist-in 3.2788 None TPO186 TPO186 XRAY 2.94 0.209 0.245 C 332.0 311.0 12 32 32 0 [[19, 315]] 1.0 4imy CMGC_CDK9_HUMAN CMGC 4.1e-80 275.1 1.0 301.0 301.0 166 167 168 170 172 48 66 70 146 148 147 149.0 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9
CMGC CDK9 CDK9_HUMAN 4IMYE P50750 8 330 372.0 AMP:401 ATPlike Active DFGin 6.7942 15.1123 BLAminus -141.41, 175.75 59.75, 77.9 -96.66, 19.65 284.44, 80.03 -69.65, -8.18 in-in in 9.1968 Saltbr-in 2.8157 HRD-in -68.02, -51.11 68.06, 12.23 in-in-in SNCiii in-in ActLoopNT-in 2.9192 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.97, 161.65 APE9-dihe-na 74.14, 135.63 APE8-dihe-in -53.23, 140.74 APE8-rot-in 294.81 APE67-dihe-in -59.86, -25.62 -47.7, -50.88 APE12-dist-in 13.4053 APE11-dist-in 11.4373 APE10-dist-in 7.0102 APE9-dist-in 3.2779 None TPO186 TPO186 XRAY 2.94 0.209 0.245 E 332.0 314.0 9 32 32 0 [[19, 315]] 1.0 4imy CMGC_CDK9_HUMAN CMGC 4.1e-80 275.1 1.0 301.0 301.0 166 167 168 170 172 48 66 70 146 148 147 149.0 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9
CMGC CDK9 CDK9_HUMAN 4IMYA P50750 8 330 372.0 AMP:401 Type1.5_Back Active DFGin 6.761 15.1264 BLAminus -140.16, 177.94 57.41, 78.2 -96.63, 19.81 285.27, 81.22 -68.88, -9.41 in-in in 9.2269 Saltbr-in 2.8489 HRD-in -67.2, -51.3 65.19, 13.63 in-in-in SNCiii in-in ActLoopNT-in 2.9203 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.99, 161.25 APE9-dihe-na 74.17, 135.57 APE8-dihe-in -52.35, 140.79 APE8-rot-in 295.69 APE67-dihe-in -60.8, -24.95 -48.08, -50.31 APE12-dist-in 13.3896 APE11-dist-in 11.433 APE10-dist-in 7.0087 APE9-dist-in 3.2703 None TPO186 TPO186 XRAY 2.94 0.209 0.245 A 332.0 315.0 8 32 32 0 [[19, 315]] 1.0 4imy CMGC_CDK9_HUMAN CMGC 4.1e-80 275.1 1.0 301.0 301.0 166 167 168 170 172 48 66 70 146 148 147 149.0 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9

PDB: 4IMY — CMGC CDK9_HUMAN

Total number of chains: 3
Active chains: 3
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4IMYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK9 CDK9_HUMAN 4IMYC P50750 8 330 372.0 AMP:401 ATPlike Active DFGin 6.7892 15.1227 BLAminus -140.61, 175.84 60.41, 77.79 -97.02, 19.01 284.69, 80.72 -68.98, -8.54 in-in in 9.2316 Saltbr-in 2.8334 HRD-in -67.68, -50.97 65.16, 13.16 in-in-in SNCiii in-in ActLoopNT-in 2.9277 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.81, 161.81 APE9-dihe-na 73.71, 135.92 APE8-dihe-in -53.34, 141.57 APE8-rot-in 294.85 APE67-dihe-in -61.16, -25.06 -47.9, -50.46 APE12-dist-in 13.386 APE11-dist-in 11.4309 APE10-dist-in 7.0061 APE9-dist-in 3.2788 None TPO186 TPO186 XRAY 2.94 0.209 0.245 C 332.0 311.0 12 32 32 0 [[19, 315]] 1.0 4imy Homo sapiens CMGC_CDK9_HUMAN CMGC 4.1e-80 275.1 1.0 301.0 301.0 166 167 168 170 172 48 66 70 146 148 147 149.0 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9
CMGC CDK9 CDK9_HUMAN 4IMYE P50750 8 330 372.0 AMP:401 ATPlike Active DFGin 6.7942 15.1123 BLAminus -141.41, 175.75 59.75, 77.9 -96.66, 19.65 284.44, 80.03 -69.65, -8.18 in-in in 9.1968 Saltbr-in 2.8157 HRD-in -68.02, -51.11 68.06, 12.23 in-in-in SNCiii in-in ActLoopNT-in 2.9192 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.97, 161.65 APE9-dihe-na 74.14, 135.63 APE8-dihe-in -53.23, 140.74 APE8-rot-in 294.81 APE67-dihe-in -59.86, -25.62 -47.7, -50.88 APE12-dist-in 13.4053 APE11-dist-in 11.4373 APE10-dist-in 7.0102 APE9-dist-in 3.2779 None TPO186 TPO186 XRAY 2.94 0.209 0.245 E 332.0 314.0 9 32 32 0 [[19, 315]] 1.0 4imy Homo sapiens CMGC_CDK9_HUMAN CMGC 4.1e-80 275.1 1.0 301.0 301.0 166 167 168 170 172 48 66 70 146 148 147 149.0 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9
CMGC CDK9 CDK9_HUMAN 4IMYA P50750 8 330 372.0 AMP:401 Type1.5_Back Active DFGin 6.761 15.1264 BLAminus -140.16, 177.94 57.41, 78.2 -96.63, 19.81 285.27, 81.22 -68.88, -9.41 in-in in 9.2269 Saltbr-in 2.8489 HRD-in -67.2, -51.3 65.19, 13.63 in-in-in SNCiii in-in ActLoopNT-in 2.9203 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.99, 161.25 APE9-dihe-na 74.17, 135.57 APE8-dihe-in -52.35, 140.79 APE8-rot-in 295.69 APE67-dihe-in -60.8, -24.95 -48.08, -50.31 APE12-dist-in 13.3896 APE11-dist-in 11.433 APE10-dist-in 7.0087 APE9-dist-in 3.2703 None TPO186 TPO186 XRAY 2.94 0.209 0.245 A 332.0 315.0 8 32 32 0 [[19, 315]] 1.0 4imy Homo sapiens CMGC_CDK9_HUMAN CMGC 4.1e-80 275.1 1.0 301.0 301.0 166 167 168 170 172 48 66 70 146 148 147 149.0 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9

PDB: 4IMY — CMGC CDK9_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name