Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKA | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.482 | 15.725 | BLAminus | -144.34, 176.17 | 62.63, 95.24 | -105.61, 23.83 | 301.64, 87.19 | -58.39, -8.3 | in-out | in | 7.943 | Saltbr-out | 4.045 | HRD-in | -70.55, -55.34 | 77.45, 11.21 | out-in-in | SNCoii | in-in | ActLoopNT-in | 3.051 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -143.05, 50.45 | APE9-dihe-na | -176.1, -155.45 | APE8-dihe-in | -86.25, 134.66 | APE8-rot-in | 312.17 | APE67-dihe-in | -46.09, -45.13 | -61.46, -48.86 | APE12-dist-in | 12.272 | APE11-dist-in | 12.268 | APE10-dist-in | 7.102 | APE9-dist-in | 3.504 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | A | 296 | 290 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKC | P49674 | 2 | 294 | 416.0 | No_ligand | No_ligand | Active | DFGin | 6.431 | 16.041 | BLAminus | -135.81, -178.21 | 53.79, 96.45 | -104.78, 21.43 | 300.63, 94.42 | -58.0, -28.51 | in-in | in | 7.496 | Saltbr-in | 3.163 | HRD-in | -66.98, -56.04 | 77.54, 4.29 | in-in-in | SNCiii | in-in | ActLoopNT-in | 3.014 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -106.35, -39.97 | APE9-dihe-na | -85.78, -155.1 | APE8-dihe-in | -86.72, 126.4 | APE8-rot-in | 300.83 | APE67-dihe-in | -44.12, -37.41 | -41.19, -62.76 | APE12-dist-in | 12.197 | APE11-dist-in | 12.117 | APE10-dist-in | 6.81 | APE9-dist-in | 3.151 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | C | 296 | 289 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKE | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.25 | 15.559 | BLAminus | -140.42, -179.36 | 53.65, 102.37 | -110.96, 31.82 | 302.97, 68.7 | -64.99, -14.4 | in-out | in | 7.819 | Saltbr-out | 5.251 | HRD-in | -68.19, -48.41 | 70.28, -1.44 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.958 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -132.06, 97.22 | APE9-dihe-na | 136.93, 176.71 | APE8-dihe-in | -72.26, 120.03 | APE8-rot-in | 314.25 | APE67-dihe-in | -47.87, -40.12 | -46.31, -48.2 | APE12-dist-in | 11.89 | APE11-dist-in | 12.295 | APE10-dist-in | 6.978 | APE9-dist-in | 3.789 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | E | 296 | 291 | 3 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKG | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Active | DFGin | 6.085 | 15.287 | BLAminus | -133.94, 176.61 | 60.07, 93.82 | -103.18, 38.11 | 317.25, 73.23 | -56.9, -47.6 | in-in | in | 7.743 | Saltbr-in | 2.375 | HRD-in | -62.54, -60.54 | 80.54, 16.27 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.957 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -140.93, 43.92 | APE9-dihe-na | -168.53, -155.09 | APE8-dihe-in | -86.3, 124.32 | APE8-rot-in | 296.58 | APE67-dihe-in | -50.57, -46.25 | -53.7, -43.28 | APE12-dist-in | 12.207 | APE11-dist-in | 12.018 | APE10-dist-in | 6.927 | APE9-dist-in | 3.724 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | G | 296 | 290 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKI | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.482 | 15.529 | BLAminus | -140.15, -174.52 | 52.72, 91.63 | -98.26, 29.42 | 299.62, 83.77 | -67.45, -21.21 | in-out | in | 8.248 | Saltbr-out | 3.998 | HRD-in | -73.08, -47.74 | 72.91, 4.35 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.978 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -132.39, 54.72 | APE9-dihe-na | 167.05, 173.0 | APE8-dihe-in | -45.39, 106.65 | APE8-rot-in | 294.04 | APE67-dihe-in | -58.57, -41.44 | -52.88, -32.68 | APE12-dist-in | 12.077 | APE11-dist-in | 12.15 | APE10-dist-in | 7.007 | APE9-dist-in | 3.861 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | I | 296 | 291 | 3 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKK | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.249 | 15.566 | BLAminus | -147.45, 172.32 | 63.97, 89.49 | -94.78, 22.45 | 302.29, 66.44 | -52.24, -13.13 | in-out | in | 7.574 | Saltbr-out | 5.809 | HRD-in | -82.45, -46.49 | 72.3, -7.99 | out-in-in | SNCoii | in-in | ActLoopNT-in | 3.029 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -72.94, -20.5 | APE9-dihe-na | -128.27, -154.79 | APE8-dihe-in | -68.42, 123.14 | APE8-rot-in | 310.94 | APE67-dihe-in | -39.07, -42.29 | -48.87, -62.43 | APE12-dist-in | 12.96 | APE11-dist-in | 12.443 | APE10-dist-in | 6.996 | APE9-dist-in | 3.652 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | K | 296 | 290 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKM | P49674 | 4 | 294 | 416.0 | No_ligand | No_ligand | Active | DFGin | 6.103 | 15.758 | BLAminus | -159.39, -171.34 | 60.52, 66.49 | -82.16, 19.62 | 306.88, 81.16 | -54.24, -26.74 | in-in | in | 8.046 | Saltbr-in | 3.493 | HRD-in | -71.87, -36.38 | 62.1, 8.89 | in-in-in | SNCiii | in-in | ActLoopNT-in | 3.027 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -135.41, 40.78 | APE9-dihe-na | -179.98, 175.59 | APE8-dihe-in | -47.95, 137.81 | APE8-rot-in | 311.18 | APE67-dihe-in | -52.24, -36.51 | -79.52, -31.01 | APE12-dist-in | 12.2 | APE11-dist-in | 12.356 | APE10-dist-in | 7.31 | APE9-dist-in | 3.89 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | M | 296 | 291 | 0 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKO | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.338 | 15.592 | BLAminus | -145.55, -174.97 | 60.0, 82.24 | -91.41, 11.2 | 302.71, 69.48 | -51.57, 1.03 | in-out | in | 8.467 | Saltbr-out | 3.928 | HRD-in | -68.03, -41.42 | 74.59, -13.5 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.907 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -94.99, -83.44 | APE9-dihe-na | -57.18, -163.09 | APE8-dihe-in | -71.18, 123.51 | APE8-rot-in | 323.79 | APE67-dihe-in | -51.76, -47.94 | -52.27, -35.36 | APE12-dist-in | 12.426 | APE11-dist-in | 12.452 | APE10-dist-in | 6.835 | APE9-dist-in | 3.507 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | O | 296 | 290 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKQ | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.214 | 16.114 | BLAminus | -126.39, -175.13 | 63.49, 91.87 | -105.9, 7.2 | 291.0, 72.75 | -51.83, -14.55 | in-out | in | 8.27 | Saltbr-out | 5.207 | HRD-in | -79.05, -45.06 | 70.05, 3.98 | out-in-in | SNCoii | in-in | ActLoopNT-in | 3.337 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -127.86, 111.64 | APE9-dihe-na | 159.68, -139.69 | APE8-dihe-in | -127.54, 103.09 | APE8-rot-in | 291.05 | APE67-dihe-in | -50.33, -33.54 | -30.33, -50.52 | APE12-dist-in | 12.89 | APE11-dist-in | 12.464 | APE10-dist-in | 6.976 | APE9-dist-in | 3.328 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | Q | 296 | 290 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKS | P49674 | 4 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.1 | 15.212 | BLAminus | -147.7, -167.9 | 41.9, 84.56 | -90.19, 3.21 | 308.49, 56.25 | -38.94, -2.41 | in-out | in | 7.724 | Saltbr-out | 5.096 | HRD-in | -66.63, -57.38 | 75.02, 10.83 | out-in-in | SNCoii | in-in | ActLoopNT-in | 3.309 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -90.84, -97.9 | APE9-dihe-na | -56.93, -140.33 | APE8-dihe-in | -91.58, 129.64 | APE8-rot-in | 316.28 | APE67-dihe-in | -38.9, -38.43 | -47.62, -61.85 | APE12-dist-in | 12.875 | APE11-dist-in | 12.577 | APE10-dist-in | 7.431 | APE9-dist-in | 3.247 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | S | 296 | 286 | 5 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKU | P49674 | 1 | 293 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 5.971 | 15.227 | BLAminus | -140.21, 174.99 | 65.5, 82.14 | -84.11, 5.21 | 304.73, 75.24 | -30.21, -19.45 | in-out | in | 8.095 | Saltbr-out | 5.592 | HRD-in | -99.31, -20.82 | 55.93, -7.36 | out-in-in | SNCoii | in-in | ActLoopNT-in | 3.017 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -113.03, -50.48 | APE9-dihe-na | -98.69, -158.93 | APE8-dihe-in | -63.66, 123.64 | APE8-rot-in | 308.41 | APE67-dihe-in | -58.18, -18.69 | -57.75, -31.27 | APE12-dist-in | 12.564 | APE11-dist-in | 12.183 | APE10-dist-in | 6.84 | APE9-dist-in | 3.675 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | U | 296 | 289 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKW | P49674 | 2 | 294 | 416.0 | No_ligand | No_ligand | Active | DFGin | 6.237 | 15.252 | BLAminus | -129.97, -165.62 | 44.31, 79.27 | -91.62, 16.51 | 304.4, 50.31 | -59.14, -4.37 | in-in | in | 7.888 | Saltbr-in | 3.323 | HRD-in | -94.36, -42.1 | 66.16, 5.53 | in-in-in | SNCiii | in-in | ActLoopNT-in | 3.152 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -131.97, -32.12 | APE9-dihe-na | -71.27, -133.58 | APE8-dihe-in | -115.71, 137.15 | APE8-rot-in | 281.72 | APE67-dihe-in | -49.78, -42.5 | -46.84, -52.73 | APE12-dist-in | 12.019 | APE11-dist-in | 12.073 | APE10-dist-in | 6.668 | APE9-dist-in | 2.891 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | W | 296 | 289 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKA | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.482 | 15.725 | BLAminus | -144.34, 176.17 | 62.63, 95.24 | -105.61, 23.83 | 301.64, 87.19 | -58.39, -8.3 | in-out | in | 7.943 | Saltbr-out | 4.045 | HRD-in | -70.55, -55.34 | 77.45, 11.21 | out-in-in | SNCoii | in-in | ActLoopNT-in | 3.051 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -143.05, 50.45 | APE9-dihe-na | -176.1, -155.45 | APE8-dihe-in | -86.25, 134.66 | APE8-rot-in | 312.17 | APE67-dihe-in | -46.09, -45.13 | -61.46, -48.86 | APE12-dist-in | 12.272 | APE11-dist-in | 12.268 | APE10-dist-in | 7.102 | APE9-dist-in | 3.504 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | A | 296 | 290 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | Homo sapiens | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKC | P49674 | 2 | 294 | 416.0 | No_ligand | No_ligand | Active | DFGin | 6.431 | 16.041 | BLAminus | -135.81, -178.21 | 53.79, 96.45 | -104.78, 21.43 | 300.63, 94.42 | -58.0, -28.51 | in-in | in | 7.496 | Saltbr-in | 3.163 | HRD-in | -66.98, -56.04 | 77.54, 4.29 | in-in-in | SNCiii | in-in | ActLoopNT-in | 3.014 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -106.35, -39.97 | APE9-dihe-na | -85.78, -155.1 | APE8-dihe-in | -86.72, 126.4 | APE8-rot-in | 300.83 | APE67-dihe-in | -44.12, -37.41 | -41.19, -62.76 | APE12-dist-in | 12.197 | APE11-dist-in | 12.117 | APE10-dist-in | 6.81 | APE9-dist-in | 3.151 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | C | 296 | 289 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | Homo sapiens | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKE | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.25 | 15.559 | BLAminus | -140.42, -179.36 | 53.65, 102.37 | -110.96, 31.82 | 302.97, 68.7 | -64.99, -14.4 | in-out | in | 7.819 | Saltbr-out | 5.251 | HRD-in | -68.19, -48.41 | 70.28, -1.44 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.958 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -132.06, 97.22 | APE9-dihe-na | 136.93, 176.71 | APE8-dihe-in | -72.26, 120.03 | APE8-rot-in | 314.25 | APE67-dihe-in | -47.87, -40.12 | -46.31, -48.2 | APE12-dist-in | 11.89 | APE11-dist-in | 12.295 | APE10-dist-in | 6.978 | APE9-dist-in | 3.789 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | E | 296 | 291 | 3 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | Homo sapiens | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKG | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Active | DFGin | 6.085 | 15.287 | BLAminus | -133.94, 176.61 | 60.07, 93.82 | -103.18, 38.11 | 317.25, 73.23 | -56.9, -47.6 | in-in | in | 7.743 | Saltbr-in | 2.375 | HRD-in | -62.54, -60.54 | 80.54, 16.27 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.957 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -140.93, 43.92 | APE9-dihe-na | -168.53, -155.09 | APE8-dihe-in | -86.3, 124.32 | APE8-rot-in | 296.58 | APE67-dihe-in | -50.57, -46.25 | -53.7, -43.28 | APE12-dist-in | 12.207 | APE11-dist-in | 12.018 | APE10-dist-in | 6.927 | APE9-dist-in | 3.724 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | G | 296 | 290 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | Homo sapiens | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKI | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.482 | 15.529 | BLAminus | -140.15, -174.52 | 52.72, 91.63 | -98.26, 29.42 | 299.62, 83.77 | -67.45, -21.21 | in-out | in | 8.248 | Saltbr-out | 3.998 | HRD-in | -73.08, -47.74 | 72.91, 4.35 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.978 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -132.39, 54.72 | APE9-dihe-na | 167.05, 173.0 | APE8-dihe-in | -45.39, 106.65 | APE8-rot-in | 294.04 | APE67-dihe-in | -58.57, -41.44 | -52.88, -32.68 | APE12-dist-in | 12.077 | APE11-dist-in | 12.15 | APE10-dist-in | 7.007 | APE9-dist-in | 3.861 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | I | 296 | 291 | 3 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | Homo sapiens | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKK | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.249 | 15.566 | BLAminus | -147.45, 172.32 | 63.97, 89.49 | -94.78, 22.45 | 302.29, 66.44 | -52.24, -13.13 | in-out | in | 7.574 | Saltbr-out | 5.809 | HRD-in | -82.45, -46.49 | 72.3, -7.99 | out-in-in | SNCoii | in-in | ActLoopNT-in | 3.029 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -72.94, -20.5 | APE9-dihe-na | -128.27, -154.79 | APE8-dihe-in | -68.42, 123.14 | APE8-rot-in | 310.94 | APE67-dihe-in | -39.07, -42.29 | -48.87, -62.43 | APE12-dist-in | 12.96 | APE11-dist-in | 12.443 | APE10-dist-in | 6.996 | APE9-dist-in | 3.652 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | K | 296 | 290 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | Homo sapiens | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKM | P49674 | 4 | 294 | 416.0 | No_ligand | No_ligand | Active | DFGin | 6.103 | 15.758 | BLAminus | -159.39, -171.34 | 60.52, 66.49 | -82.16, 19.62 | 306.88, 81.16 | -54.24, -26.74 | in-in | in | 8.046 | Saltbr-in | 3.493 | HRD-in | -71.87, -36.38 | 62.1, 8.89 | in-in-in | SNCiii | in-in | ActLoopNT-in | 3.027 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -135.41, 40.78 | APE9-dihe-na | -179.98, 175.59 | APE8-dihe-in | -47.95, 137.81 | APE8-rot-in | 311.18 | APE67-dihe-in | -52.24, -36.51 | -79.52, -31.01 | APE12-dist-in | 12.2 | APE11-dist-in | 12.356 | APE10-dist-in | 7.31 | APE9-dist-in | 3.89 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | M | 296 | 291 | 0 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | Homo sapiens | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKO | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.338 | 15.592 | BLAminus | -145.55, -174.97 | 60.0, 82.24 | -91.41, 11.2 | 302.71, 69.48 | -51.57, 1.03 | in-out | in | 8.467 | Saltbr-out | 3.928 | HRD-in | -68.03, -41.42 | 74.59, -13.5 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.907 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -94.99, -83.44 | APE9-dihe-na | -57.18, -163.09 | APE8-dihe-in | -71.18, 123.51 | APE8-rot-in | 323.79 | APE67-dihe-in | -51.76, -47.94 | -52.27, -35.36 | APE12-dist-in | 12.426 | APE11-dist-in | 12.452 | APE10-dist-in | 6.835 | APE9-dist-in | 3.507 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | O | 296 | 290 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | Homo sapiens | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKQ | P49674 | 1 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.214 | 16.114 | BLAminus | -126.39, -175.13 | 63.49, 91.87 | -105.9, 7.2 | 291.0, 72.75 | -51.83, -14.55 | in-out | in | 8.27 | Saltbr-out | 5.207 | HRD-in | -79.05, -45.06 | 70.05, 3.98 | out-in-in | SNCoii | in-in | ActLoopNT-in | 3.337 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -127.86, 111.64 | APE9-dihe-na | 159.68, -139.69 | APE8-dihe-in | -127.54, 103.09 | APE8-rot-in | 291.05 | APE67-dihe-in | -50.33, -33.54 | -30.33, -50.52 | APE12-dist-in | 12.89 | APE11-dist-in | 12.464 | APE10-dist-in | 6.976 | APE9-dist-in | 3.328 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | Q | 296 | 290 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | Homo sapiens | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKS | P49674 | 4 | 294 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 6.1 | 15.212 | BLAminus | -147.7, -167.9 | 41.9, 84.56 | -90.19, 3.21 | 308.49, 56.25 | -38.94, -2.41 | in-out | in | 7.724 | Saltbr-out | 5.096 | HRD-in | -66.63, -57.38 | 75.02, 10.83 | out-in-in | SNCoii | in-in | ActLoopNT-in | 3.309 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -90.84, -97.9 | APE9-dihe-na | -56.93, -140.33 | APE8-dihe-in | -91.58, 129.64 | APE8-rot-in | 316.28 | APE67-dihe-in | -38.9, -38.43 | -47.62, -61.85 | APE12-dist-in | 12.875 | APE11-dist-in | 12.577 | APE10-dist-in | 7.431 | APE9-dist-in | 3.247 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | S | 296 | 286 | 5 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | Homo sapiens | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKU | P49674 | 1 | 293 | 416.0 | No_ligand | No_ligand | Inactive | DFGin | 5.971 | 15.227 | BLAminus | -140.21, 174.99 | 65.5, 82.14 | -84.11, 5.21 | 304.73, 75.24 | -30.21, -19.45 | in-out | in | 8.095 | Saltbr-out | 5.592 | HRD-in | -99.31, -20.82 | 55.93, -7.36 | out-in-in | SNCoii | in-in | ActLoopNT-in | 3.017 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -113.03, -50.48 | APE9-dihe-na | -98.69, -158.93 | APE8-dihe-in | -63.66, 123.64 | APE8-rot-in | 308.41 | APE67-dihe-in | -58.18, -18.69 | -57.75, -31.27 | APE12-dist-in | 12.564 | APE11-dist-in | 12.183 | APE10-dist-in | 6.84 | APE9-dist-in | 3.675 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | U | 296 | 289 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | Homo sapiens | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| CK1 | CSNK1E | KC1E_HUMAN | 4HOKW | P49674 | 2 | 294 | 416.0 | No_ligand | No_ligand | Active | DFGin | 6.237 | 15.252 | BLAminus | -129.97, -165.62 | 44.31, 79.27 | -91.62, 16.51 | 304.4, 50.31 | -59.14, -4.37 | in-in | in | 7.888 | Saltbr-in | 3.323 | HRD-in | -94.36, -42.1 | 66.16, 5.53 | in-in-in | SNCiii | in-in | ActLoopNT-in | 3.152 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -131.97, -32.12 | APE9-dihe-na | -71.27, -133.58 | APE8-dihe-in | -115.71, 137.15 | APE8-rot-in | 281.72 | APE67-dihe-in | -49.78, -42.5 | -46.84, -52.73 | APE12-dist-in | 12.019 | APE11-dist-in | 12.073 | APE10-dist-in | 6.668 | APE9-dist-in | 2.891 | None | None | None | XRAY | 2.77 | 0.241 | 0.262 | W | 296 | 289 | 4 | 0 | 0 | 0 | [[9, 275]] | 1.0 | 4hok | Homo sapiens | CK1_CSNK1E_HUMAN | CK1 | 7.3e-123 | 415.0 | 1 | 262 | 262 | 148 | 149 | 150 | 152 | 154 | 38 | 52 | 56 | 125 | 127 | 126 | 128 | 195 | 183 | 178 | 177 | 176 | 175 | 174 | 173 | 172 | 83 | Casein kinase I isoform epsilon |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|