PDB: 4GL9 — TYR JAK2_MOUSE

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

PDB: 4GL9 — TYR JAK2_MOUSE

Total number of chains: 4
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4GL9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_MOUSE 4GL9A Q62120 843 1130 1132.0 IZA:62001 Type1 Inactive DFGin 5.7577 14.5353 BLAminus -131.1, 175.47 54.64, 81.14 -92.19, 32.98 300.1, 95.95 -58.27, -44.01 in-in in 9.0349 Saltbr-in 3.3604 HRD-in -73.72, -44.47 64.56, -43.96 in-in-out SNCiio in-out ActLoopNT-in 3.1066 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -55.67, 134.18 APE9-dihe-in -146.45, 151.12 APE8-dihe-in -74.76, 79.94 APE8-rot-na 27.08 APE67-dihe-in -82.75, -26.09 -66.14, -14.69 APE12-dist-na 11.8979 APE11-dist-na 11.3463 APE10-dist-na 12.1263 APE9-dist-out 8.4949 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 3.9 0.254 0.281 A 297.0 284.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4gl9 Mus musculus TYR_JAK2-2_MOUSE TYR 7.3e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_MOUSE 4GL9B Q62120 843 1130 1132.0 IZA:61201 Type1 Inactive DFGin 5.9255 13.9565 BLAminus -131.65, 175.34 54.28, 82.24 -93.18, 32.79 301.63, 90.67 -58.15, -43.04 in-in in 8.7836 Saltbr-in 2.7775 HRD-in -75.15, -44.99 64.86, -43.48 in-in-out SNCiio in-out ActLoopNT-in 3.1731 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -55.23, 133.88 APE9-dihe-in -145.62, 151.28 APE8-dihe-in -74.33, 80.39 APE8-rot-na 26.93 APE67-dihe-in -82.22, -25.66 -66.02, -15.3 APE12-dist-na 10.8545 APE11-dist-na 10.5463 APE10-dist-na 11.5765 APE9-dist-out 8.1552 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 3.9 0.254 0.281 B 297.0 282.0 6 31 31 0 [[545, 807], [849, 1125]] 2.0 4gl9 Mus musculus TYR_JAK2-2_MOUSE TYR 7.3e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_MOUSE 4GL9C Q62120 843 1130 1132.0 IZA:61201 Type1 Inactive DFGin 6.0667 14.3386 BLAminus -130.77, 175.48 54.57, 81.25 -92.89, 33.32 299.53, 89.15 -58.8, -44.7 in-in in 9.076 Saltbr-in 2.9964 HRD-in -74.67, -44.19 64.59, -44.72 in-in-out SNCiio in-out ActLoopNT-in 2.94 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -53.52, 135.21 APE9-dihe-in -144.8, 151.59 APE8-dihe-in -74.44, 79.48 APE8-rot-na 27.41 APE67-dihe-in -84.46, -26.89 -66.72, -16.8 APE12-dist-na 11.515 APE11-dist-na 11.1772 APE10-dist-na 11.8564 APE9-dist-out 8.4803 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 3.9 0.254 0.281 C 297.0 284.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4gl9 Mus musculus TYR_JAK2-2_MOUSE TYR 7.3e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_MOUSE 4GL9D Q62120 843 1130 1132.0 IZA:61201 Type1 Active DFGin 6.1126 14.1044 BLAminus -130.51, 174.55 54.31, 81.77 -91.69, 33.32 299.7, 91.33 -57.81, -43.55 in-in in 9.0369 Saltbr-in 3.3257 HRD-in -75.42, -43.64 65.18, -41.08 in-in-in SNCiii in-in ActLoopNT-in 3.1093 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -56.34, 133.7 APE9-dihe-in -146.39, 149.67 APE8-dihe-in -76.13, 80.18 APE8-rot-na 27.12 APE67-dihe-in -82.31, -26.02 -65.86, -16.39 APE12-dist-na 11.4611 APE11-dist-na 10.3143 APE10-dist-na 10.7895 APE9-dist-in 7.989 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 3.9 0.254 0.281 D 297.0 284.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4gl9 Mus musculus TYR_JAK2-2_MOUSE TYR 7.3e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 4GL9 — TYR JAK2_MOUSE

Total number of chains: 4
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4GL9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_MOUSE 4GL9A Q62120 843 1130 1132.0 IZA:62001 Type1 Inactive DFGin 5.7577 14.5353 BLAminus -131.1, 175.47 54.64, 81.14 -92.19, 32.98 300.1, 95.95 -58.27, -44.01 in-in in 9.0349 Saltbr-in 3.3604 HRD-in -73.72, -44.47 64.56, -43.96 in-in-out SNCiio in-out ActLoopNT-in 3.1066 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -55.67, 134.18 APE9-dihe-in -146.45, 151.12 APE8-dihe-in -74.76, 79.94 APE8-rot-na 27.08 APE67-dihe-in -82.75, -26.09 -66.14, -14.69 APE12-dist-na 11.8979 APE11-dist-na 11.3463 APE10-dist-na 12.1263 APE9-dist-out 8.4949 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 3.9 0.254 0.281 A 297.0 284.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4gl9 Mus musculus TYR_JAK2-2_MOUSE TYR 7.3e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_MOUSE 4GL9B Q62120 843 1130 1132.0 IZA:61201 Type1 Inactive DFGin 5.9255 13.9565 BLAminus -131.65, 175.34 54.28, 82.24 -93.18, 32.79 301.63, 90.67 -58.15, -43.04 in-in in 8.7836 Saltbr-in 2.7775 HRD-in -75.15, -44.99 64.86, -43.48 in-in-out SNCiio in-out ActLoopNT-in 3.1731 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -55.23, 133.88 APE9-dihe-in -145.62, 151.28 APE8-dihe-in -74.33, 80.39 APE8-rot-na 26.93 APE67-dihe-in -82.22, -25.66 -66.02, -15.3 APE12-dist-na 10.8545 APE11-dist-na 10.5463 APE10-dist-na 11.5765 APE9-dist-out 8.1552 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 3.9 0.254 0.281 B 297.0 282.0 6 31 31 0 [[545, 807], [849, 1125]] 2.0 4gl9 Mus musculus TYR_JAK2-2_MOUSE TYR 7.3e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_MOUSE 4GL9C Q62120 843 1130 1132.0 IZA:61201 Type1 Inactive DFGin 6.0667 14.3386 BLAminus -130.77, 175.48 54.57, 81.25 -92.89, 33.32 299.53, 89.15 -58.8, -44.7 in-in in 9.076 Saltbr-in 2.9964 HRD-in -74.67, -44.19 64.59, -44.72 in-in-out SNCiio in-out ActLoopNT-in 2.94 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -53.52, 135.21 APE9-dihe-in -144.8, 151.59 APE8-dihe-in -74.44, 79.48 APE8-rot-na 27.41 APE67-dihe-in -84.46, -26.89 -66.72, -16.8 APE12-dist-na 11.515 APE11-dist-na 11.1772 APE10-dist-na 11.8564 APE9-dist-out 8.4803 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 3.9 0.254 0.281 C 297.0 284.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4gl9 Mus musculus TYR_JAK2-2_MOUSE TYR 7.3e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_MOUSE 4GL9D Q62120 843 1130 1132.0 IZA:61201 Type1 Active DFGin 6.1126 14.1044 BLAminus -130.51, 174.55 54.31, 81.77 -91.69, 33.32 299.7, 91.33 -57.81, -43.55 in-in in 9.0369 Saltbr-in 3.3257 HRD-in -75.42, -43.64 65.18, -41.08 in-in-in SNCiii in-in ActLoopNT-in 3.1093 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -56.34, 133.7 APE9-dihe-in -146.39, 149.67 APE8-dihe-in -76.13, 80.18 APE8-rot-na 27.12 APE67-dihe-in -82.31, -26.02 -65.86, -16.39 APE12-dist-na 11.4611 APE11-dist-na 10.3143 APE10-dist-na 10.7895 APE9-dist-in 7.989 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 3.9 0.254 0.281 D 297.0 284.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4gl9 Mus musculus TYR_JAK2-2_MOUSE TYR 7.3e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2