PDB: 3ZC6 — TYR JAK3_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 3ZC6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN 3ZC6A P52333 814 1100 1124.0 VFC:2103 Type1 Inactive DFGin 6.3992 14.249 BLAminus -132.73, -176.21 56.45, 83.25 -97.56, 22.77 285.82, 73.7 -62.6, -27.55 in-in in 8.2919 Saltbr-in 2.8022 HRD-in -72.44, -47.03 73.15, -6.89 in-in-out SNCiio in-out ActLoopNT-in 2.7419 ActLoopCT-out TYR APEdihe_noiai APEdist_aaai APE10-dihe-none 999.0, 118.21 APE9-dihe-out -83.58, -179.01 APE8-dihe-in -60.9, 137.23 APE8-rot-na 332.96 APE67-dihe-in -76.45, -9.26 -65.3, -16.84 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 9.5354 APE9-dist-in 5.9074 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.42 0.193 0.254 A 288.0 279.0 8 31 27 4 [[521, 779], [822, 1097]] 2.0 3zc6 TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6B P52333 813 1100 1124.0 VFC:2103 Type1 None DFGin 6.2181 14.0462 BLAminus -128.88, -176.96 59.69, 81.97 -99.61, 22.0 289.18, 82.46 -63.53, -20.72 in-in in 8.2087 Saltbr-in 2.7991 HRD-in -71.31, -49.71 79.31, 3.34 in-in-none SNCiin in-none ActLoopNT-in 2.7475 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 25.15 APE9-dihe-in -99.95, 171.81 APE8-dihe-in -50.02, 112.29 APE8-rot-na 325.04 APE67-dihe-in -73.29, -4.3 -58.87, -25.22 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 10.4818 APE9-dist-in 6.8402 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.42 0.193 0.254 B 288.0 278.0 10 31 27 4 [[521, 779], [822, 1097]] 2.0 3zc6 TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6C P52333 814 1100 1124.0 VFC:2103 Type1 Inactive DFGin 6.2807 14.0027 BLAminus -123.64, -177.74 61.16, 80.91 -97.9, 27.04 288.23, 77.53 -66.72, -26.1 in-in in 8.1905 Saltbr-in 2.6842 HRD-in -72.21, -46.31 77.05, -24.4 in-in-out SNCiio in-out ActLoopNT-in 2.7606 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -54.85 APE8-dihe-in -77.18, 80.1 APE8-rot-na 33.09 APE67-dihe-in -76.9, -10.93 -67.13, -29.18 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.1774 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.42 0.193 0.254 C 288.0 277.0 10 31 27 4 [[521, 779], [822, 1097]] 2.0 3zc6 TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6D P52333 814 1100 1124.0 VFC:2103 Type1 None DFGin 6.3147 14.132 BLAminus -134.59, -176.68 59.2, 81.95 -97.58, 24.75 285.45, 76.49 -66.73, -25.04 in-in in 8.057 Saltbr-in 2.7416 HRD-in -74.86, -52.02 77.99, -12.75 in-in-none SNCiin in-none ActLoopNT-in 2.7303 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 79.2 APE8-rot-na 32.25 APE67-dihe-in -80.63, -5.09 -78.85, -21.32 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.42 0.193 0.254 D 288.0 269.0 18 31 26 5 [[521, 779], [822, 1097]] 2.0 3zc6 TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

PDB: 3ZC6 — TYR JAK3_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 3ZC6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN 3ZC6A P52333 814 1100 1124.0 VFC:2103 Type1 Inactive DFGin 6.3992 14.249 BLAminus -132.73, -176.21 56.45, 83.25 -97.56, 22.77 285.82, 73.7 -62.6, -27.55 in-in in 8.2919 Saltbr-in 2.8022 HRD-in -72.44, -47.03 73.15, -6.89 in-in-out SNCiio in-out ActLoopNT-in 2.7419 ActLoopCT-out TYR APEdihe_noiai APEdist_aaai APE10-dihe-none 999.0, 118.21 APE9-dihe-out -83.58, -179.01 APE8-dihe-in -60.9, 137.23 APE8-rot-na 332.96 APE67-dihe-in -76.45, -9.26 -65.3, -16.84 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 9.5354 APE9-dist-in 5.9074 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.42 0.193 0.254 A 288.0 279.0 8 31 27 4 [[521, 779], [822, 1097]] 2.0 3zc6 Homo sapiens TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6B P52333 813 1100 1124.0 VFC:2103 Type1 None DFGin 6.2181 14.0462 BLAminus -128.88, -176.96 59.69, 81.97 -99.61, 22.0 289.18, 82.46 -63.53, -20.72 in-in in 8.2087 Saltbr-in 2.7991 HRD-in -71.31, -49.71 79.31, 3.34 in-in-none SNCiin in-none ActLoopNT-in 2.7475 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 25.15 APE9-dihe-in -99.95, 171.81 APE8-dihe-in -50.02, 112.29 APE8-rot-na 325.04 APE67-dihe-in -73.29, -4.3 -58.87, -25.22 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 10.4818 APE9-dist-in 6.8402 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.42 0.193 0.254 B 288.0 278.0 10 31 27 4 [[521, 779], [822, 1097]] 2.0 3zc6 Homo sapiens TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6C P52333 814 1100 1124.0 VFC:2103 Type1 Inactive DFGin 6.2807 14.0027 BLAminus -123.64, -177.74 61.16, 80.91 -97.9, 27.04 288.23, 77.53 -66.72, -26.1 in-in in 8.1905 Saltbr-in 2.6842 HRD-in -72.21, -46.31 77.05, -24.4 in-in-out SNCiio in-out ActLoopNT-in 2.7606 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -54.85 APE8-dihe-in -77.18, 80.1 APE8-rot-na 33.09 APE67-dihe-in -76.9, -10.93 -67.13, -29.18 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.1774 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.42 0.193 0.254 C 288.0 277.0 10 31 27 4 [[521, 779], [822, 1097]] 2.0 3zc6 Homo sapiens TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6D P52333 814 1100 1124.0 VFC:2103 Type1 None DFGin 6.3147 14.132 BLAminus -134.59, -176.68 59.2, 81.95 -97.58, 24.75 285.45, 76.49 -66.73, -25.04 in-in in 8.057 Saltbr-in 2.7416 HRD-in -74.86, -52.02 77.99, -12.75 in-in-none SNCiin in-none ActLoopNT-in 2.7303 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 79.2 APE8-rot-na 32.25 APE67-dihe-in -80.63, -5.09 -78.85, -21.32 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.42 0.193 0.254 D 288.0 269.0 18 31 26 5 [[521, 779], [822, 1097]] 2.0 3zc6 Homo sapiens TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

PDB: 3ZC6 — TYR JAK3_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name