PDB: 3O17 — CMGC MK08_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 3O17A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK8 MK08_HUMAN 3O17A P45983 7 363 427.0 No_ligand No_ligand Active DFGin 6.1281 13.9918 BLAminus -143.08, -155.15 4.86, 119.05 -115.61, 15.13 291.48, 95.12 -55.48, -42.85 in-in in 8.9255 Saltbr-in 2.9771 HRD-in -88.38, -43.35 58.03, 10.08 in-in-in SNCiii in-in ActLoopNT-in 2.3731 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -76.55, -54.88 APE9-dihe-na -56.03, 107.98 APE8-dihe-in -41.53, 122.11 APE8-rot-in 303.39 APE67-dihe-in -26.7, -32.66 -31.75, -85.44 APE12-dist-in 10.5963 APE11-dist-in 11.6428 APE10-dist-in 6.8427 APE9-dist-in 4.5653 T183E,Y185E None None XRAY 3.0 0.263 0.308 A 370.0 357.0 0 27 27 0 [[26, 321]] 1.0 3o17 CMGC_MAPK8_HUMAN CMGC 1.6e-83 286.4 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 3O17B P45983 7 363 427.0 No_ligand No_ligand Active DFGin 6.3772 13.3535 BLAminus -141.52, 176.46 56.9, 126.68 -136.61, 6.27 299.25, 120.4 -50.46, -23.38 in-in in 9.2139 Saltbr-in 3.0929 HRD-in -88.24, -52.87 72.9, -9.22 in-in-in SNCiii in-in ActLoopNT-in 2.4939 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -59.17, -32.26 APE9-dihe-na -88.08, 142.34 APE8-dihe-in -62.23, 117.26 APE8-rot-in 321.66 APE67-dihe-in -47.49, -37.82 -30.24, -67.12 APE12-dist-in 11.7384 APE11-dist-in 12.4339 APE10-dist-in 7.0415 APE9-dist-in 4.5416 T183E,Y185E None None XRAY 3.0 0.263 0.308 B 370.0 357.0 0 27 27 0 [[26, 321]] 1.0 3o17 CMGC_MAPK8_HUMAN CMGC 1.6e-83 286.4 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8

PDB: 3O17 — CMGC MK08_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 3O17A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK8 MK08_HUMAN 3O17A P45983 7 363 427.0 No_ligand No_ligand Active DFGin 6.1281 13.9918 BLAminus -143.08, -155.15 4.86, 119.05 -115.61, 15.13 291.48, 95.12 -55.48, -42.85 in-in in 8.9255 Saltbr-in 2.9771 HRD-in -88.38, -43.35 58.03, 10.08 in-in-in SNCiii in-in ActLoopNT-in 2.3731 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -76.55, -54.88 APE9-dihe-na -56.03, 107.98 APE8-dihe-in -41.53, 122.11 APE8-rot-in 303.39 APE67-dihe-in -26.7, -32.66 -31.75, -85.44 APE12-dist-in 10.5963 APE11-dist-in 11.6428 APE10-dist-in 6.8427 APE9-dist-in 4.5653 T183E,Y185E None None XRAY 3.0 0.263 0.308 A 370.0 357.0 0 27 27 0 [[26, 321]] 1.0 3o17 Homo sapiens CMGC_MAPK8_HUMAN CMGC 1.6e-83 286.4 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 3O17B P45983 7 363 427.0 No_ligand No_ligand Active DFGin 6.3772 13.3535 BLAminus -141.52, 176.46 56.9, 126.68 -136.61, 6.27 299.25, 120.4 -50.46, -23.38 in-in in 9.2139 Saltbr-in 3.0929 HRD-in -88.24, -52.87 72.9, -9.22 in-in-in SNCiii in-in ActLoopNT-in 2.4939 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -59.17, -32.26 APE9-dihe-na -88.08, 142.34 APE8-dihe-in -62.23, 117.26 APE8-rot-in 321.66 APE67-dihe-in -47.49, -37.82 -30.24, -67.12 APE12-dist-in 11.7384 APE11-dist-in 12.4339 APE10-dist-in 7.0415 APE9-dist-in 4.5416 T183E,Y185E None None XRAY 3.0 0.263 0.308 B 370.0 357.0 0 27 27 0 [[26, 321]] 1.0 3o17 Homo sapiens CMGC_MAPK8_HUMAN CMGC 1.6e-83 286.4 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8

PDB: 3O17 — CMGC MK08_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name