PDB: 3KXX — TYR FGFR1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 3KXXB
DFGin BLBminus 1 25.0% 3KXXA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 3KXXB P11362 460 764 822.0 No_ligand No_ligand Inactive DFGin 7.061 14.507 BLAminus -138.91, 177.11 64.42, 63.57 -90.83, 31.94 294.07, 81.15 -71.04, -30.05 in-in in 7.234 Saltbr-in 3.199 HRD-out -89.94, 81.9 -57.82, 5.46 in-in-in SNCiii in-in ActLoopNT-in 2.908 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -92.01, 74.51 APE9-dihe-in -144.18, 139.02 APE8-dihe-in -51.42, 121.01 APE8-rot-na 327.88 APE67-dihe-in -76.85, -17.4 -68.16, -22.5 APE12-dist-na 14.893 APE11-dist-na 10.36 APE10-dist-na 9.133 APE9-dist-in 5.752 C488A,R577E,C584S None None XRAY 3.2 0.224 0.263 B 317 305 0 0 0 0 [[478, 756]] 1.0 3kxx TYR_FGFR1_HUMAN TYR 2.4e-104 354.2 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KXXC P11362 458 762 822.0 No_ligand No_ligand Inactive DFGin 7.139 13.992 BLAminus -138.07, -172.42 62.91, 62.15 -92.81, 13.58 296.2, 98.02 -70.01, -16.73 in-in in 7.243 Saltbr-in 2.637 HRD-out -88.37, 88.38 -55.25, -6.98 in-in-in SNCiii in-in ActLoopNT-in 2.968 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -93.88, 68.46 APE9-dihe-in -154.11, 147.86 APE8-dihe-in -47.33, 131.68 APE8-rot-na 28.97 APE67-dihe-in -56.58, -13.9 -82.3, -38.63 APE12-dist-na 15.086 APE11-dist-na 10.333 APE10-dist-na 8.947 APE9-dist-in 6.261 C488A,R577E,C584S None None XRAY 3.2 0.224 0.263 C 317 286 19 0 0 0 [[478, 756]] 1.0 3kxx TYR_FGFR1_HUMAN TYR 2.4e-104 354.2 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KXXD P11362 458 762 822.0 No_ligand No_ligand Inactive DFGin 6.502 13.671 BLAminus -133.51, -161.48 51.6, 74.09 -99.67, 22.58 293.84, 93.72 -66.62, -32.71 in-in in 7.529 Saltbr-in 3.458 HRD-out -84.43, 73.53 -41.76, -24.93 in-in-in SNCiii in-in ActLoopNT-in 3.114 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.31, 77.29 APE9-dihe-in -147.89, 135.68 APE8-dihe-in -51.4, 116.54 APE8-rot-na 326.12 APE67-dihe-in -63.39, 3.02 -61.34, -39.64 APE12-dist-na 15.473 APE11-dist-na 10.561 APE10-dist-na 8.835 APE9-dist-in 6.24 C488A,R577E,C584S None None XRAY 3.2 0.224 0.263 D 317 286 19 0 0 0 [[478, 756]] 1.0 3kxx TYR_FGFR1_HUMAN TYR 2.4e-104 354.2 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KXXA P11362 461 765 822.0 No_ligand No_ligand Inactive DFGin 6.889 14.259 BLBminus -140.37, -169.46 63.26, 50.32 -78.18, 162.76 296.3, 66.09 151.64, -37.0 in-in in 7.017 Saltbr-in 2.83 HRD-out -100.04, 84.29 -55.69, -0.92 in-in-out SNCiio in-out ActLoopNT-in 2.902 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -104.55, 44.24 APE9-dihe-in -122.5, 136.32 APE8-dihe-in -50.57, 127.21 APE8-rot-na 327.84 APE67-dihe-in -76.36, 2.91 -67.27, -29.4 APE12-dist-na 14.337 APE11-dist-na 9.735 APE10-dist-na 7.861 APE9-dist-in 5.347 C488A,R577E,C584S None None XRAY 3.2 0.224 0.263 A 317 305 0 0 0 0 [[478, 756]] 1.0 3kxx TYR_FGFR1_HUMAN TYR 2.4e-104 354.2 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1

PDB: 3KXX — TYR FGFR1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 3KXXB
DFGin BLBminus 1 25.0% 3KXXA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 3KXXB P11362 460 764 822.0 No_ligand No_ligand Inactive DFGin 7.061 14.507 BLAminus -138.91, 177.11 64.42, 63.57 -90.83, 31.94 294.07, 81.15 -71.04, -30.05 in-in in 7.234 Saltbr-in 3.199 HRD-out -89.94, 81.9 -57.82, 5.46 in-in-in SNCiii in-in ActLoopNT-in 2.908 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -92.01, 74.51 APE9-dihe-in -144.18, 139.02 APE8-dihe-in -51.42, 121.01 APE8-rot-na 327.88 APE67-dihe-in -76.85, -17.4 -68.16, -22.5 APE12-dist-na 14.893 APE11-dist-na 10.36 APE10-dist-na 9.133 APE9-dist-in 5.752 C488A,R577E,C584S None None XRAY 3.2 0.224 0.263 B 317 305 0 0 0 0 [[478, 756]] 1.0 3kxx Homo sapiens TYR_FGFR1_HUMAN TYR 2.4e-104 354.2 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KXXC P11362 458 762 822.0 No_ligand No_ligand Inactive DFGin 7.139 13.992 BLAminus -138.07, -172.42 62.91, 62.15 -92.81, 13.58 296.2, 98.02 -70.01, -16.73 in-in in 7.243 Saltbr-in 2.637 HRD-out -88.37, 88.38 -55.25, -6.98 in-in-in SNCiii in-in ActLoopNT-in 2.968 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -93.88, 68.46 APE9-dihe-in -154.11, 147.86 APE8-dihe-in -47.33, 131.68 APE8-rot-na 28.97 APE67-dihe-in -56.58, -13.9 -82.3, -38.63 APE12-dist-na 15.086 APE11-dist-na 10.333 APE10-dist-na 8.947 APE9-dist-in 6.261 C488A,R577E,C584S None None XRAY 3.2 0.224 0.263 C 317 286 19 0 0 0 [[478, 756]] 1.0 3kxx Homo sapiens TYR_FGFR1_HUMAN TYR 2.4e-104 354.2 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KXXD P11362 458 762 822.0 No_ligand No_ligand Inactive DFGin 6.502 13.671 BLAminus -133.51, -161.48 51.6, 74.09 -99.67, 22.58 293.84, 93.72 -66.62, -32.71 in-in in 7.529 Saltbr-in 3.458 HRD-out -84.43, 73.53 -41.76, -24.93 in-in-in SNCiii in-in ActLoopNT-in 3.114 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.31, 77.29 APE9-dihe-in -147.89, 135.68 APE8-dihe-in -51.4, 116.54 APE8-rot-na 326.12 APE67-dihe-in -63.39, 3.02 -61.34, -39.64 APE12-dist-na 15.473 APE11-dist-na 10.561 APE10-dist-na 8.835 APE9-dist-in 6.24 C488A,R577E,C584S None None XRAY 3.2 0.224 0.263 D 317 286 19 0 0 0 [[478, 756]] 1.0 3kxx Homo sapiens TYR_FGFR1_HUMAN TYR 2.4e-104 354.2 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KXXA P11362 461 765 822.0 No_ligand No_ligand Inactive DFGin 6.889 14.259 BLBminus -140.37, -169.46 63.26, 50.32 -78.18, 162.76 296.3, 66.09 151.64, -37.0 in-in in 7.017 Saltbr-in 2.83 HRD-out -100.04, 84.29 -55.69, -0.92 in-in-out SNCiio in-out ActLoopNT-in 2.902 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -104.55, 44.24 APE9-dihe-in -122.5, 136.32 APE8-dihe-in -50.57, 127.21 APE8-rot-na 327.84 APE67-dihe-in -76.36, 2.91 -67.27, -29.4 APE12-dist-na 14.337 APE11-dist-na 9.735 APE10-dist-na 7.861 APE9-dist-in 5.347 C488A,R577E,C584S None None XRAY 3.2 0.224 0.263 A 317 305 0 0 0 0 [[478, 756]] 1.0 3kxx Homo sapiens TYR_FGFR1_HUMAN TYR 2.4e-104 354.2 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1

PDB: 3KXX — TYR FGFR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name