PDB: 2WO6 — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2WO6A
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 2WO6A Q13627 133 481 763.0 D15:60600 Type1 Active DFGin 7.448 15.138 BLAminus -113.71, 170.1 69.22, 79.01 -93.27, 30.89 281.47, 79.67 -74.92, -25.98 in-in in 8.538 Saltbr-in 2.478 HRD-in -60.74, -47.85 77.07, -4.65 in-in-in SNCiii in-in ActLoopNT-in 2.791 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -109.22, 165.87 APE9-dihe-na 75.78, 143.18 APE8-dihe-in -71.63, 143.35 APE8-rot-in 298.65 APE67-dihe-in -54.81, -27.06 -54.61, -51.13 APE12-dist-in 13.979 APE11-dist-in 11.967 APE10-dist-in 7.387 APE9-dist-in 3.275 None PTR321 PTR321 XRAY 2.5 0.19 0.229 A 382 345 4 0 0 0 [[159, 479]] 1.0 2wo6 CMGC_DYRK1A_HUMAN CMGC 1e-90 310.0 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 2WO6B Q13627 136 480 763.0 D15:60600 Type1 Active DFGin 7.392 15.045 BLAminus -114.82, 170.21 64.99, 84.74 -96.3, 34.41 283.13, 77.19 -78.24, -22.43 in-in in 9.207 Saltbr-in 2.725 HRD-in -63.58, -44.58 74.08, -1.57 in-in-in SNCiii in-in ActLoopNT-in 2.791 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.01, 169.27 APE9-dihe-na 76.89, 144.45 APE8-dihe-in -76.49, 136.75 APE8-rot-in 283.78 APE67-dihe-in -66.31, -25.74 -49.43, -39.9 APE12-dist-in 12.633 APE11-dist-in 11.105 APE10-dist-in 6.823 APE9-dist-in 3.096 None PTR321 PTR321 XRAY 2.5 0.19 0.229 B 382 340 5 0 0 0 [[159, 479]] 1.0 2wo6 CMGC_DYRK1A_HUMAN CMGC 1e-90 310.0 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 2WO6 — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2WO6A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 2WO6A Q13627 133 481 763.0 D15:60600 Type1 Active DFGin 7.448 15.138 BLAminus -113.71, 170.1 69.22, 79.01 -93.27, 30.89 281.47, 79.67 -74.92, -25.98 in-in in 8.538 Saltbr-in 2.478 HRD-in -60.74, -47.85 77.07, -4.65 in-in-in SNCiii in-in ActLoopNT-in 2.791 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -109.22, 165.87 APE9-dihe-na 75.78, 143.18 APE8-dihe-in -71.63, 143.35 APE8-rot-in 298.65 APE67-dihe-in -54.81, -27.06 -54.61, -51.13 APE12-dist-in 13.979 APE11-dist-in 11.967 APE10-dist-in 7.387 APE9-dist-in 3.275 None PTR321 PTR321 XRAY 2.5 0.19 0.229 A 382 345 4 0 0 0 [[159, 479]] 1.0 2wo6 Homo sapiens CMGC_DYRK1A_HUMAN CMGC 1e-90 310.0 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 2WO6B Q13627 136 480 763.0 D15:60600 Type1 Active DFGin 7.392 15.045 BLAminus -114.82, 170.21 64.99, 84.74 -96.3, 34.41 283.13, 77.19 -78.24, -22.43 in-in in 9.207 Saltbr-in 2.725 HRD-in -63.58, -44.58 74.08, -1.57 in-in-in SNCiii in-in ActLoopNT-in 2.791 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.01, 169.27 APE9-dihe-na 76.89, 144.45 APE8-dihe-in -76.49, 136.75 APE8-rot-in 283.78 APE67-dihe-in -66.31, -25.74 -49.43, -39.9 APE12-dist-in 12.633 APE11-dist-in 11.105 APE10-dist-in 6.823 APE9-dist-in 3.096 None PTR321 PTR321 XRAY 2.5 0.19 0.229 B 382 340 5 0 0 0 [[159, 479]] 1.0 2wo6 Homo sapiens CMGC_DYRK1A_HUMAN CMGC 1e-90 310.0 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 2WO6 — CMGC DYR1A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name