PDB: 2W1I — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2W1IB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 2W1IB O60674 843 1132 1132.0 No_ligand No_ligand Inactive DFGin 5.9971 13.8453 BLAminus -129.87, -167.39 53.3, 77.87 -90.81, 22.6 298.76, 93.77 -65.07, -29.79 in-out in 8.4285 Saltbr-out 3.8488 HRD-in -57.34, -41.14 62.34, 9.12 out-in-in SNCoii in-in ActLoopNT-in 2.7209 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -53.98, 136.0 APE9-dihe-in -141.41, 130.69 APE8-dihe-in -74.31, 69.47 APE8-rot-na 31.54 APE67-dihe-in -71.28, -6.63 -56.8, -34.08 APE12-dist-na 10.4807 APE11-dist-na 9.4804 APE10-dist-na 10.2514 APE9-dist-in 6.7862 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.6 0.209 0.295 B 326.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 2w1i TYR_JAK2-2_HUMAN TYR 3.6e-87 298.0 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2W1IA O60674 843 1132 1132.0 L0I:2133 Type1 Active DFGin 6.0925 14.0902 BLAminus -142.48, -169.83 51.96, 80.95 -93.55, 29.52 297.23, 91.38 -67.11, -31.24 in-in in 8.3967 Saltbr-in 3.0634 HRD-in -62.15, -46.21 66.4, 9.56 in-in-in SNCiii in-in ActLoopNT-in 2.6778 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -58.29, 137.22 APE9-dihe-in -138.71, 128.52 APE8-dihe-in -70.92, 67.85 APE8-rot-na 29.05 APE67-dihe-in -68.18, -7.39 -56.23, -38.03 APE12-dist-na 10.6088 APE11-dist-na 9.4047 APE10-dist-na 10.3336 APE9-dist-in 6.8851 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.6 0.209 0.295 A 326.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 2w1i TYR_JAK2-2_HUMAN TYR 3.6e-87 298.0 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 2W1I — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2W1IB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 2W1IB O60674 843 1132 1132.0 No_ligand No_ligand Inactive DFGin 5.9971 13.8453 BLAminus -129.87, -167.39 53.3, 77.87 -90.81, 22.6 298.76, 93.77 -65.07, -29.79 in-out in 8.4285 Saltbr-out 3.8488 HRD-in -57.34, -41.14 62.34, 9.12 out-in-in SNCoii in-in ActLoopNT-in 2.7209 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -53.98, 136.0 APE9-dihe-in -141.41, 130.69 APE8-dihe-in -74.31, 69.47 APE8-rot-na 31.54 APE67-dihe-in -71.28, -6.63 -56.8, -34.08 APE12-dist-na 10.4807 APE11-dist-na 9.4804 APE10-dist-na 10.2514 APE9-dist-in 6.7862 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.6 0.209 0.295 B 326.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 2w1i Homo sapiens TYR_JAK2-2_HUMAN TYR 3.6e-87 298.0 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2W1IA O60674 843 1132 1132.0 L0I:2133 Type1 Active DFGin 6.0925 14.0902 BLAminus -142.48, -169.83 51.96, 80.95 -93.55, 29.52 297.23, 91.38 -67.11, -31.24 in-in in 8.3967 Saltbr-in 3.0634 HRD-in -62.15, -46.21 66.4, 9.56 in-in-in SNCiii in-in ActLoopNT-in 2.6778 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -58.29, 137.22 APE9-dihe-in -138.71, 128.52 APE8-dihe-in -70.92, 67.85 APE8-rot-na 29.05 APE67-dihe-in -68.18, -7.39 -56.23, -38.03 APE12-dist-na 10.6088 APE11-dist-na 9.4047 APE10-dist-na 10.3336 APE9-dist-in 6.8851 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.6 0.209 0.295 A 326.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 2w1i Homo sapiens TYR_JAK2-2_HUMAN TYR 3.6e-87 298.0 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 2W1I — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name