PDB: 2PWL — TYR FGFR2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2PWLB

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 2PWLA P21802 467 764 821.0 ACP:300 ATPlike Inactive DFGin 6.451 14.178 BLAminus -131.61, -167.38 56.51, 73.64 -92.98, 26.06 293.6, 74.93 -63.45, -20.7 in-in in 7.586 Saltbr-in 2.856 HRD-in -77.4, -49.09 71.28, -7.85 in-in-out SNCiio in-out ActLoopNT-in 2.885 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -113.03, 20.75 APE9-dihe-in -94.74, 135.38 APE8-dihe-in -58.69, 123.68 APE8-rot-na 326.81 APE67-dihe-in -69.99, -5.92 -52.74, -45.54 APE12-dist-na 10.002 APE11-dist-na 10.678 APE10-dist-na 7.432 APE9-dist-in 4.749 C491A,N549H None None XRAY 2.4 0.21 0.238 A 324 284 14 0 0 0 [[481, 759]] 1.0 2pwl TYR_FGFR2_HUMAN TYR 3.1e-104 353.8 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PWLB P21802 468 765 821.0 ACP:300 ATPlike Inactive DFGin 6.439 14.28 BLAminus -131.94, -168.62 54.17, 75.02 -93.02, 25.01 292.99, 76.23 -61.28, -25.59 in-in in 7.692 Saltbr-in 3.07 HRD-in -69.87, -47.96 69.48, -8.93 in-in-out SNCiio in-out ActLoopNT-in 2.916 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.23, 16.85 APE9-dihe-in -95.43, 136.0 APE8-dihe-in -55.13, 121.27 APE8-rot-na 324.13 APE67-dihe-in -66.61, -7.86 -55.94, -44.16 APE12-dist-na 10.089 APE11-dist-na 10.854 APE10-dist-na 7.485 APE9-dist-in 4.912 C491A,N549H None None XRAY 2.4 0.21 0.238 B 324 286 12 0 0 0 [[481, 759]] 1.0 2pwl TYR_FGFR2_HUMAN TYR 3.1e-104 353.8 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 2PWL — TYR FGFR2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2PWLB

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 2PWLA P21802 467 764 821.0 ACP:300 ATPlike Inactive DFGin 6.451 14.178 BLAminus -131.61, -167.38 56.51, 73.64 -92.98, 26.06 293.6, 74.93 -63.45, -20.7 in-in in 7.586 Saltbr-in 2.856 HRD-in -77.4, -49.09 71.28, -7.85 in-in-out SNCiio in-out ActLoopNT-in 2.885 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -113.03, 20.75 APE9-dihe-in -94.74, 135.38 APE8-dihe-in -58.69, 123.68 APE8-rot-na 326.81 APE67-dihe-in -69.99, -5.92 -52.74, -45.54 APE12-dist-na 10.002 APE11-dist-na 10.678 APE10-dist-na 7.432 APE9-dist-in 4.749 C491A,N549H None None XRAY 2.4 0.21 0.238 A 324 284 14 0 0 0 [[481, 759]] 1.0 2pwl Homo sapiens TYR_FGFR2_HUMAN TYR 3.1e-104 353.8 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PWLB P21802 468 765 821.0 ACP:300 ATPlike Inactive DFGin 6.439 14.28 BLAminus -131.94, -168.62 54.17, 75.02 -93.02, 25.01 292.99, 76.23 -61.28, -25.59 in-in in 7.692 Saltbr-in 3.07 HRD-in -69.87, -47.96 69.48, -8.93 in-in-out SNCiio in-out ActLoopNT-in 2.916 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.23, 16.85 APE9-dihe-in -95.43, 136.0 APE8-dihe-in -55.13, 121.27 APE8-rot-na 324.13 APE67-dihe-in -66.61, -7.86 -55.94, -44.16 APE12-dist-na 10.089 APE11-dist-na 10.854 APE10-dist-na 7.485 APE9-dist-in 4.912 C491A,N549H None None XRAY 2.4 0.21 0.238 B 324 286 12 0 0 0 [[481, 759]] 1.0 2pwl Homo sapiens TYR_FGFR2_HUMAN TYR 3.1e-104 353.8 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 2PWL — TYR FGFR2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name