PDB: 2PVY — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 2PVYA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 2PVYA P21802 467 764 821.0 ACP:802 ATPlike Inactive DFGin 6.75 14.274 BLAminus -142.14, -176.01 63.9, 72.69 -96.2, 30.01 293.76, 86.07 -65.9, -30.73 in-in in 7.547 Saltbr-in 2.852 HRD-in -84.99, -48.7 74.29, -16.98 in-in-out SNCiio in-out ActLoopNT-in 2.809 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.15, 32.71 APE9-dihe-in -103.67, 126.67 APE8-dihe-in -51.63, 122.63 APE8-rot-na 323.69 APE67-dihe-in -64.04, -12.74 -56.98, -40.88 APE12-dist-na 14.814 APE11-dist-na 10.095 APE10-dist-na 7.537 APE9-dist-in 4.955 C491A,K659N None None XRAY 2.2 0.236 0.276 A 324 288 10 0 0 0 [[481, 759]] 1.0 2pvy TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYB P21802 462 764 821.0 ACP:8002 ATPlike Inactive DFGin 6.635 14.065 BLAminus -144.27, -177.95 57.14, 77.78 -93.97, 24.89 293.34, 84.21 -55.49, -34.1 in-in in 7.316 Saltbr-in 2.847 HRD-in -81.21, -48.71 71.97, -12.52 in-in-out SNCiio in-out ActLoopNT-in 2.852 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -106.68, 30.22 APE9-dihe-in -107.46, 135.49 APE8-dihe-in -57.98, 120.91 APE8-rot-na 329.38 APE67-dihe-in -64.69, -5.42 -51.47, -46.8 APE12-dist-na 999.0 APE11-dist-na 10.694 APE10-dist-na 7.435 APE9-dist-in 5.066 C491A,K659N None None XRAY 2.2 0.236 0.276 B 324 286 17 0 0 6 [[481, 759]] 1.0 2pvy TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYC P21802 462 764 821.0 ACP:802 ATPlike Inactive DFGin 6.693 14.018 BLAminus -131.41, -174.32 49.42, 82.58 -94.81, 27.78 293.52, 79.4 -60.72, -24.91 in-in in 7.229 Saltbr-in 3.577 HRD-in -81.5, -47.6 72.07, -14.53 in-in-out SNCiio in-out ActLoopNT-in 2.794 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.89, 24.55 APE9-dihe-in -101.87, 134.03 APE8-dihe-in -55.3, 120.87 APE8-rot-na 330.19 APE67-dihe-in -64.04, -6.89 -51.83, -46.76 APE12-dist-na 14.316 APE11-dist-na 10.323 APE10-dist-na 7.438 APE9-dist-in 5.069 C491A,K659N None None XRAY 2.2 0.236 0.276 C 324 285 18 0 0 5 [[481, 759]] 1.0 2pvy TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYD P21802 467 764 821.0 ACP:802 ATPlike Inactive DFGin 6.944 14.261 BLAminus -139.76, -174.3 61.15, 74.17 -97.41, 31.68 293.81, 79.18 -66.75, -30.92 in-in in 7.298 Saltbr-in 3.036 HRD-in -85.65, -49.02 75.46, -18.01 in-in-out SNCiio in-out ActLoopNT-in 2.811 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.37, 33.11 APE9-dihe-in -102.8, 126.29 APE8-dihe-in -51.84, 123.89 APE8-rot-na 324.49 APE67-dihe-in -63.66, -13.12 -61.69, -37.66 APE12-dist-na 14.828 APE11-dist-na 10.092 APE10-dist-na 7.57 APE9-dist-in 4.968 C491A,K659N None None XRAY 2.2 0.236 0.276 D 324 283 15 0 0 0 [[481, 759]] 1.0 2pvy TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 2PVY — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 2PVYA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 2PVYA P21802 467 764 821.0 ACP:802 ATPlike Inactive DFGin 6.75 14.274 BLAminus -142.14, -176.01 63.9, 72.69 -96.2, 30.01 293.76, 86.07 -65.9, -30.73 in-in in 7.547 Saltbr-in 2.852 HRD-in -84.99, -48.7 74.29, -16.98 in-in-out SNCiio in-out ActLoopNT-in 2.809 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.15, 32.71 APE9-dihe-in -103.67, 126.67 APE8-dihe-in -51.63, 122.63 APE8-rot-na 323.69 APE67-dihe-in -64.04, -12.74 -56.98, -40.88 APE12-dist-na 14.814 APE11-dist-na 10.095 APE10-dist-na 7.537 APE9-dist-in 4.955 C491A,K659N None None XRAY 2.2 0.236 0.276 A 324 288 10 0 0 0 [[481, 759]] 1.0 2pvy Homo sapiens TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYB P21802 462 764 821.0 ACP:8002 ATPlike Inactive DFGin 6.635 14.065 BLAminus -144.27, -177.95 57.14, 77.78 -93.97, 24.89 293.34, 84.21 -55.49, -34.1 in-in in 7.316 Saltbr-in 2.847 HRD-in -81.21, -48.71 71.97, -12.52 in-in-out SNCiio in-out ActLoopNT-in 2.852 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -106.68, 30.22 APE9-dihe-in -107.46, 135.49 APE8-dihe-in -57.98, 120.91 APE8-rot-na 329.38 APE67-dihe-in -64.69, -5.42 -51.47, -46.8 APE12-dist-na 999.0 APE11-dist-na 10.694 APE10-dist-na 7.435 APE9-dist-in 5.066 C491A,K659N None None XRAY 2.2 0.236 0.276 B 324 286 17 0 0 6 [[481, 759]] 1.0 2pvy Homo sapiens TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYC P21802 462 764 821.0 ACP:802 ATPlike Inactive DFGin 6.693 14.018 BLAminus -131.41, -174.32 49.42, 82.58 -94.81, 27.78 293.52, 79.4 -60.72, -24.91 in-in in 7.229 Saltbr-in 3.577 HRD-in -81.5, -47.6 72.07, -14.53 in-in-out SNCiio in-out ActLoopNT-in 2.794 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.89, 24.55 APE9-dihe-in -101.87, 134.03 APE8-dihe-in -55.3, 120.87 APE8-rot-na 330.19 APE67-dihe-in -64.04, -6.89 -51.83, -46.76 APE12-dist-na 14.316 APE11-dist-na 10.323 APE10-dist-na 7.438 APE9-dist-in 5.069 C491A,K659N None None XRAY 2.2 0.236 0.276 C 324 285 18 0 0 5 [[481, 759]] 1.0 2pvy Homo sapiens TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYD P21802 467 764 821.0 ACP:802 ATPlike Inactive DFGin 6.944 14.261 BLAminus -139.76, -174.3 61.15, 74.17 -97.41, 31.68 293.81, 79.18 -66.75, -30.92 in-in in 7.298 Saltbr-in 3.036 HRD-in -85.65, -49.02 75.46, -18.01 in-in-out SNCiio in-out ActLoopNT-in 2.811 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.37, 33.11 APE9-dihe-in -102.8, 126.29 APE8-dihe-in -51.84, 123.89 APE8-rot-na 324.49 APE67-dihe-in -63.66, -13.12 -61.69, -37.66 APE12-dist-na 14.828 APE11-dist-na 10.092 APE10-dist-na 7.57 APE9-dist-in 4.968 C491A,K659N None None XRAY 2.2 0.236 0.276 D 324 283 15 0 0 0 [[481, 759]] 1.0 2pvy Homo sapiens TYR_FGFR2_HUMAN TYR 2.8e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 2PVY — TYR FGFR2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name