PDB: 2IW8 — CMGC CDK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2IW8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2IW8A P24941 1 297 298.0 4SP:61298 Type1 Active DFGin 6.9074 14.8759 BLAminus -128.94, 178.15 45.79, 77.82 -89.54, 20.73 278.33, 75.94 -62.77, -23.59 in-in in 8.52 Saltbr-in 2.6783 HRD-in -82.44, -53.34 71.08, 17.45 in-in-in SNCiii in-in ActLoopNT-in 2.8988 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.18, 148.54 APE9-dihe-na 67.67, 128.23 APE8-dihe-in -55.32, 132.5 APE8-rot-in 304.46 APE67-dihe-in -56.59, -27.86 -44.81, -49.42 APE12-dist-in 12.9473 APE11-dist-in 10.4394 APE10-dist-in 7.3158 APE9-dist-in 3.2532 F82H,L83V,H84D TPO160 TPO160 XRAY 2.3 0.214 0.255 A 302.0 297.0 0 28 28 0 [[4, 286]] 1.0 2iw8 CMGC_CDK2_HUMAN CMGC 1.1e-89 307.1 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2IW8C P24941 1 296 298.0 4SP:61297 Type1 Active DFGin 6.7761 14.9929 BLAminus -119.11, -171.67 36.55, 74.77 -80.97, 23.02 280.6, 75.2 -62.4, -19.17 in-in in 8.6717 Saltbr-in 2.4825 HRD-in -81.37, -52.61 71.76, 20.77 in-in-in SNCiii in-in ActLoopNT-in 2.9714 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.18, 153.02 APE9-dihe-na 61.13, 127.0 APE8-dihe-in -47.11, 147.78 APE8-rot-in 315.45 APE67-dihe-in -43.58, -23.45 -49.47, -61.15 APE12-dist-in 12.9056 APE11-dist-in 9.9417 APE10-dist-in 7.2042 APE9-dist-in 3.417 F82H,L83V,H84D TPO160 TPO160 XRAY 2.3 0.214 0.255 C 302.0 265.0 31 28 28 0 [[4, 286]] 1.0 2iw8 CMGC_CDK2_HUMAN CMGC 1.1e-89 307.1 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

PDB: 2IW8 — CMGC CDK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2IW8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2IW8A P24941 1 297 298.0 4SP:61298 Type1 Active DFGin 6.9074 14.8759 BLAminus -128.94, 178.15 45.79, 77.82 -89.54, 20.73 278.33, 75.94 -62.77, -23.59 in-in in 8.52 Saltbr-in 2.6783 HRD-in -82.44, -53.34 71.08, 17.45 in-in-in SNCiii in-in ActLoopNT-in 2.8988 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.18, 148.54 APE9-dihe-na 67.67, 128.23 APE8-dihe-in -55.32, 132.5 APE8-rot-in 304.46 APE67-dihe-in -56.59, -27.86 -44.81, -49.42 APE12-dist-in 12.9473 APE11-dist-in 10.4394 APE10-dist-in 7.3158 APE9-dist-in 3.2532 F82H,L83V,H84D TPO160 TPO160 XRAY 2.3 0.214 0.255 A 302.0 297.0 0 28 28 0 [[4, 286]] 1.0 2iw8 Homo sapiens CMGC_CDK2_HUMAN CMGC 1.1e-89 307.1 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2IW8C P24941 1 296 298.0 4SP:61297 Type1 Active DFGin 6.7761 14.9929 BLAminus -119.11, -171.67 36.55, 74.77 -80.97, 23.02 280.6, 75.2 -62.4, -19.17 in-in in 8.6717 Saltbr-in 2.4825 HRD-in -81.37, -52.61 71.76, 20.77 in-in-in SNCiii in-in ActLoopNT-in 2.9714 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.18, 153.02 APE9-dihe-na 61.13, 127.0 APE8-dihe-in -47.11, 147.78 APE8-rot-in 315.45 APE67-dihe-in -43.58, -23.45 -49.47, -61.15 APE12-dist-in 12.9056 APE11-dist-in 9.9417 APE10-dist-in 7.2042 APE9-dist-in 3.417 F82H,L83V,H84D TPO160 TPO160 XRAY 2.3 0.214 0.255 C 302.0 265.0 31 28 28 0 [[4, 286]] 1.0 2iw8 Homo sapiens CMGC_CDK2_HUMAN CMGC 1.1e-89 307.1 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

PDB: 2IW8 — CMGC CDK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name