PDB: 2H96 — CMGC MK08_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2H96A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK8 MK08_HUMAN 2H96A P45983 7 364 427.0 893:60901 Type1 Active DFGin 5.7466 14.0711 BLAminus -142.02, 170.57 47.6, 140.71 -141.49, -1.15 291.84, 115.53 -55.85, -8.38 in-in in 9.1022 Saltbr-in 2.8225 HRD-in -85.69, -41.32 64.83, 4.35 in-in-in SNCiii in-in ActLoopNT-in 2.806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -74.81, -40.52 APE9-dihe-na -68.31, 154.87 APE8-dihe-in -75.38, 102.01 APE8-rot-in 313.08 APE67-dihe-in -53.52, -10.26 -11.43, -68.01 APE12-dist-in 11.968 APE11-dist-in 12.5208 APE10-dist-in 7.0412 APE9-dist-in 4.4506 T183E,Y185E None None XRAY 3.0 0.243 0.278 A 370.0 358.0 0 27 27 0 [[26, 321]] 1.0 2h96 CMGC_MAPK8_HUMAN CMGC 2.6e-83 285.6 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 2H96B P45983 7 364 427.0 893:60902 Type1 Active DFGin 5.8069 14.0678 BLAminus -144.72, 174.09 54.02, 123.29 -119.24, -14.41 278.05, 179.66 -39.96, -62.74 in-in in 9.0689 Saltbr-in 2.9733 HRD-in -74.32, -61.93 80.7, -10.76 in-in-in SNCiii in-in ActLoopNT-in 2.8668 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -88.3, -36.87 APE9-dihe-na -83.37, 136.31 APE8-dihe-in -75.86, 124.1 APE8-rot-in 311.58 APE67-dihe-in -48.77, -30.54 -42.37, -58.0 APE12-dist-in 11.8616 APE11-dist-in 12.7575 APE10-dist-in 7.2009 APE9-dist-in 5.2463 T183E,Y185E None None XRAY 3.0 0.243 0.278 B 370.0 358.0 0 27 27 0 [[26, 321]] 1.0 2h96 CMGC_MAPK8_HUMAN CMGC 2.6e-83 285.6 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8

PDB: 2H96 — CMGC MK08_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2H96A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK8 MK08_HUMAN 2H96A P45983 7 364 427.0 893:60901 Type1 Active DFGin 5.7466 14.0711 BLAminus -142.02, 170.57 47.6, 140.71 -141.49, -1.15 291.84, 115.53 -55.85, -8.38 in-in in 9.1022 Saltbr-in 2.8225 HRD-in -85.69, -41.32 64.83, 4.35 in-in-in SNCiii in-in ActLoopNT-in 2.806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -74.81, -40.52 APE9-dihe-na -68.31, 154.87 APE8-dihe-in -75.38, 102.01 APE8-rot-in 313.08 APE67-dihe-in -53.52, -10.26 -11.43, -68.01 APE12-dist-in 11.968 APE11-dist-in 12.5208 APE10-dist-in 7.0412 APE9-dist-in 4.4506 T183E,Y185E None None XRAY 3.0 0.243 0.278 A 370.0 358.0 0 27 27 0 [[26, 321]] 1.0 2h96 Homo sapiens CMGC_MAPK8_HUMAN CMGC 2.6e-83 285.6 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 2H96B P45983 7 364 427.0 893:60902 Type1 Active DFGin 5.8069 14.0678 BLAminus -144.72, 174.09 54.02, 123.29 -119.24, -14.41 278.05, 179.66 -39.96, -62.74 in-in in 9.0689 Saltbr-in 2.9733 HRD-in -74.32, -61.93 80.7, -10.76 in-in-in SNCiii in-in ActLoopNT-in 2.8668 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -88.3, -36.87 APE9-dihe-na -83.37, 136.31 APE8-dihe-in -75.86, 124.1 APE8-rot-in 311.58 APE67-dihe-in -48.77, -30.54 -42.37, -58.0 APE12-dist-in 11.8616 APE11-dist-in 12.7575 APE10-dist-in 7.2009 APE9-dist-in 5.2463 T183E,Y185E None None XRAY 3.0 0.243 0.278 B 370.0 358.0 0 27 27 0 [[26, 321]] 1.0 2h96 Homo sapiens CMGC_MAPK8_HUMAN CMGC 2.6e-83 285.6 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8

PDB: 2H96 — CMGC MK08_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name