PDB: 1CM8 — CMGC MK12_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 1CM8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK12 MK12_HUMAN 1CM8A P53778 8 353 367.0 ANP:60400 ATPlike Active DFGin 6.9648 14.7742 BLAminus -109.08, -177.81 49.88, 82.62 -94.66, 21.96 279.65, 74.31 -61.38, -21.21 in-in in 9.0 Saltbr-in 2.7767 HRD-in -80.35, -48.18 64.34, 20.91 in-in-in SNCiii in-in ActLoopNT-in 2.7927 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.88, 159.85 APE9-dihe-na 73.62, 141.22 APE8-dihe-in -70.32, 134.6 APE8-rot-in 295.09 APE67-dihe-in -62.17, -12.08 -34.13, -61.33 APE12-dist-in 11.6036 APE11-dist-in 10.9558 APE10-dist-in 6.9911 APE9-dist-in 3.072 None TPO183,PTR185 TPO183,PTR185 XRAY 2.4 0.232 0.283 A 367.0 329.0 6 25 25 0 [[27, 311]] 1.0 1cm8 CMGC_MAPK12_HUMAN CMGC 5.6e-85 291.2 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 1CM8B P53778 8 353 367.0 ANP:61400 ATPlike Active DFGin 6.9649 14.7941 BLAminus -106.93, -177.79 50.51, 81.99 -94.3, 22.09 279.91, 74.94 -61.07, -21.75 in-in in 9.0314 Saltbr-in 2.7588 HRD-in -80.7, -47.04 63.03, 19.82 in-in-in SNCiii in-in ActLoopNT-in 2.8171 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.88, 160.62 APE9-dihe-na 73.12, 141.25 APE8-dihe-in -70.38, 133.34 APE8-rot-in 295.67 APE67-dihe-in -62.05, -11.85 -33.55, -61.0 APE12-dist-in 11.6132 APE11-dist-in 10.95 APE10-dist-in 6.9956 APE9-dist-in 3.0483 None TPO183,PTR185 TPO183,PTR185 XRAY 2.4 0.232 0.283 B 367.0 329.0 6 25 25 0 [[27, 311]] 1.0 1cm8 CMGC_MAPK12_HUMAN CMGC 5.6e-85 291.2 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12

PDB: 1CM8 — CMGC MK12_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 1CM8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK12 MK12_HUMAN 1CM8A P53778 8 353 367.0 ANP:60400 ATPlike Active DFGin 6.9648 14.7742 BLAminus -109.08, -177.81 49.88, 82.62 -94.66, 21.96 279.65, 74.31 -61.38, -21.21 in-in in 9.0 Saltbr-in 2.7767 HRD-in -80.35, -48.18 64.34, 20.91 in-in-in SNCiii in-in ActLoopNT-in 2.7927 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.88, 159.85 APE9-dihe-na 73.62, 141.22 APE8-dihe-in -70.32, 134.6 APE8-rot-in 295.09 APE67-dihe-in -62.17, -12.08 -34.13, -61.33 APE12-dist-in 11.6036 APE11-dist-in 10.9558 APE10-dist-in 6.9911 APE9-dist-in 3.072 None TPO183,PTR185 TPO183,PTR185 XRAY 2.4 0.232 0.283 A 367.0 329.0 6 25 25 0 [[27, 311]] 1.0 1cm8 Homo sapiens CMGC_MAPK12_HUMAN CMGC 5.6e-85 291.2 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 1CM8B P53778 8 353 367.0 ANP:61400 ATPlike Active DFGin 6.9649 14.7941 BLAminus -106.93, -177.79 50.51, 81.99 -94.3, 22.09 279.91, 74.94 -61.07, -21.75 in-in in 9.0314 Saltbr-in 2.7588 HRD-in -80.7, -47.04 63.03, 19.82 in-in-in SNCiii in-in ActLoopNT-in 2.8171 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.88, 160.62 APE9-dihe-na 73.12, 141.25 APE8-dihe-in -70.38, 133.34 APE8-rot-in 295.67 APE67-dihe-in -62.05, -11.85 -33.55, -61.0 APE12-dist-in 11.6132 APE11-dist-in 10.95 APE10-dist-in 6.9956 APE9-dist-in 3.0483 None TPO183,PTR185 TPO183,PTR185 XRAY 2.4 0.232 0.283 B 367.0 329.0 6 25 25 0 [[27, 311]] 1.0 1cm8 Homo sapiens CMGC_MAPK12_HUMAN CMGC 5.6e-85 291.2 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12

PDB: 1CM8 — CMGC MK12_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name