Ligand: ZGY

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7MKXA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 7MKXA P24941 1 296 298.0 ZGY:60301 Type1 Inactive DFGin 6.578 14.754 BLAminus -140.81, 169.83 55.63, 72.68 -84.48, 27.67 300.0, 1.18 -58.86, -37.01 in-out in 8.233 Saltbr-out 4.248 HRD-in -77.94, -57.51 70.73, 8.99 out-in-in SNCoii in-in ActLoopNT-in 3.013 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.98, 89.93 APE9-dihe-na -179.85, 149.23 APE8-dihe-in -56.28, 134.25 APE8-rot-in 299.51 APE67-dihe-in -61.78, -21.13 -52.49, -48.37 APE12-dist-in 13.006 APE11-dist-in 10.709 APE10-dist-in 6.616 APE9-dist-in 3.694 None TPO160 TPO160 XRAY 3.08 0.248 0.289 A 303 296 0 0 0 0 [[4, 286]] 1.0 7mkx CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7MKXC P24941 1 296 298.0 ZGY:60301 Type1 Active DFGin 6.277 15.114 BLAminus -140.36, 171.89 55.66, 70.68 -84.32, 23.75 280.3, 66.0 -61.29, -36.7 in-in in 8.541 Saltbr-in 3.198 HRD-in -78.5, -56.26 72.21, 7.67 in-in-in SNCiii in-in ActLoopNT-in 2.774 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.45, 89.97 APE9-dihe-na -178.93, 147.76 APE8-dihe-in -57.48, 133.34 APE8-rot-in 301.11 APE67-dihe-in -60.92, -21.4 -53.06, -47.27 APE12-dist-in 12.957 APE11-dist-in 11.013 APE10-dist-in 6.455 APE9-dist-in 3.741 None TPO160 TPO160 XRAY 3.08 0.248 0.289 C 303 296 0 0 0 0 [[4, 286]] 1.0 7mkx CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: ZGY

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7MKXA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 7MKXA P24941 1 296 298.0 ZGY:60301 Type1 Inactive DFGin 6.578 14.754 BLAminus -140.81, 169.83 55.63, 72.68 -84.48, 27.67 300.0, 1.18 -58.86, -37.01 in-out in 8.233 Saltbr-out 4.248 HRD-in -77.94, -57.51 70.73, 8.99 out-in-in SNCoii in-in ActLoopNT-in 3.013 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.98, 89.93 APE9-dihe-na -179.85, 149.23 APE8-dihe-in -56.28, 134.25 APE8-rot-in 299.51 APE67-dihe-in -61.78, -21.13 -52.49, -48.37 APE12-dist-in 13.006 APE11-dist-in 10.709 APE10-dist-in 6.616 APE9-dist-in 3.694 None TPO160 TPO160 XRAY 3.08 0.248 0.289 A 303 296 0 0 0 0 [[4, 286]] 1.0 7mkx Homo sapiens CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7MKXC P24941 1 296 298.0 ZGY:60301 Type1 Active DFGin 6.277 15.114 BLAminus -140.36, 171.89 55.66, 70.68 -84.32, 23.75 280.3, 66.0 -61.29, -36.7 in-in in 8.541 Saltbr-in 3.198 HRD-in -78.5, -56.26 72.21, 7.67 in-in-in SNCiii in-in ActLoopNT-in 2.774 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.45, 89.97 APE9-dihe-na -178.93, 147.76 APE8-dihe-in -57.48, 133.34 APE8-rot-in 301.11 APE67-dihe-in -60.92, -21.4 -53.06, -47.27 APE12-dist-in 12.957 APE11-dist-in 11.013 APE10-dist-in 6.455 APE9-dist-in 3.741 None TPO160 TPO160 XRAY 3.08 0.248 0.289 C 303 296 0 0 0 0 [[4, 286]] 1.0 7mkx Homo sapiens CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: ZGY

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name