Ligand: WF7

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7KIEA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 7KIEA P21802 466 766 821.0 WF7:801 Type1 Inactive DFGin 6.977 14.848 BLAminus -131.39, -169.16 54.75, 74.84 -95.86, 20.26 282.29, 75.53 -45.07, -46.66 in-in in 7.611 Saltbr-in 3.048 HRD-in -91.29, -46.71 82.94, -9.97 in-in-out SNCiio in-out ActLoopNT-in 2.987 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -125.11, 21.7 APE9-dihe-in -95.02, 131.64 APE8-dihe-in -52.4, 118.95 APE8-rot-na 324.83 APE67-dihe-in -75.99, -13.6 -53.13, -38.79 APE12-dist-na 10.033 APE11-dist-na 10.705 APE10-dist-na 7.483 APE9-dist-in 4.839 V564F None None XRAY 2.47 0.202 0.229 A 308 291 10 0 0 0 [[481, 759]] 1.0 7kie TYR_FGFR2_HUMAN TYR 2.7e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 7KIEB P21802 466 767 821.0 WF7:801 Type1 Inactive DFGin 7.035 14.809 BLAminus -137.38, -176.99 66.42, 65.65 -89.69, 13.43 284.31, 71.08 -48.41, -38.08 in-in in 7.448 Saltbr-in 3.232 HRD-in -77.26, -55.81 80.7, -9.45 in-in-out SNCiio in-out ActLoopNT-in 2.851 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.89, 17.38 APE9-dihe-in -97.25, 125.97 APE8-dihe-in -52.01, 125.72 APE8-rot-na 329.53 APE67-dihe-in -76.39, -7.41 -69.78, -34.58 APE12-dist-na 10.09 APE11-dist-na 10.736 APE10-dist-na 7.332 APE9-dist-in 4.938 V564F None None XRAY 2.47 0.202 0.229 B 308 292 10 0 0 0 [[481, 759]] 1.0 7kie TYR_FGFR2_HUMAN TYR 2.7e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

Ligand: WF7

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7KIEA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 7KIEA P21802 466 766 821.0 WF7:801 Type1 Inactive DFGin 6.977 14.848 BLAminus -131.39, -169.16 54.75, 74.84 -95.86, 20.26 282.29, 75.53 -45.07, -46.66 in-in in 7.611 Saltbr-in 3.048 HRD-in -91.29, -46.71 82.94, -9.97 in-in-out SNCiio in-out ActLoopNT-in 2.987 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -125.11, 21.7 APE9-dihe-in -95.02, 131.64 APE8-dihe-in -52.4, 118.95 APE8-rot-na 324.83 APE67-dihe-in -75.99, -13.6 -53.13, -38.79 APE12-dist-na 10.033 APE11-dist-na 10.705 APE10-dist-na 7.483 APE9-dist-in 4.839 V564F None None XRAY 2.47 0.202 0.229 A 308 291 10 0 0 0 [[481, 759]] 1.0 7kie Homo sapiens TYR_FGFR2_HUMAN TYR 2.7e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 7KIEB P21802 466 767 821.0 WF7:801 Type1 Inactive DFGin 7.035 14.809 BLAminus -137.38, -176.99 66.42, 65.65 -89.69, 13.43 284.31, 71.08 -48.41, -38.08 in-in in 7.448 Saltbr-in 3.232 HRD-in -77.26, -55.81 80.7, -9.45 in-in-out SNCiio in-out ActLoopNT-in 2.851 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.89, 17.38 APE9-dihe-in -97.25, 125.97 APE8-dihe-in -52.01, 125.72 APE8-rot-na 329.53 APE67-dihe-in -76.39, -7.41 -69.78, -34.58 APE12-dist-na 10.09 APE11-dist-na 10.736 APE10-dist-na 7.332 APE9-dist-in 4.938 V564F None None XRAY 2.47 0.202 0.229 B 308 292 10 0 0 0 [[481, 759]] 1.0 7kie Homo sapiens TYR_FGFR2_HUMAN TYR 2.7e-104 354.0 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

Ligand: WF7

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name