Ligand: WEG

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7KHJA

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 7KHJA P10721 566 931 976.0 WEG:61001 Type1 Active DFGin 6.611 13.898 BLAminus -132.69, -177.38 50.04, 76.8 -92.52, 23.6 290.02, 76.67 -56.27, -37.04 in-in in 7.663 Saltbr-in 3.294 HRD-in -79.35, -42.57 69.41, 10.19 in-in-in SNCiii in-in ActLoopNT-in 2.937 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.7, 141.7 APE9-dihe-in -138.2, 151.32 APE8-dihe-in -79.54, 72.69 APE8-rot-na 30.14 APE67-dihe-in -69.61, -6.54 -46.54, -51.48 APE12-dist-na 999.0 APE11-dist-na 8.404 APE10-dist-na 11.082 APE9-dist-in 6.956 None None None XRAY 2.8 0.245 0.286 A 335 288 20 0 0 2 [[589, 926]] 1.0 7khj TYR_KIT_HUMAN TYR 1.1e-104 355.4 1 261 261 809 810 811 813 815 623 640 644 789 791 790 792 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7KHJB P10721 571 930 976.0 WEG:61001 Type1 Active DFGin 6.555 14.026 BLAminus -133.9, -173.37 50.96, 78.54 -96.13, 23.55 287.55, 72.9 -57.94, -35.66 in-in in 7.809 Saltbr-in 3.12 HRD-in -77.71, -37.21 66.91, 8.51 in-in-in SNCiii in-in ActLoopNT-in 3.022 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -98.94, 146.27 APE9-dihe-in -140.07, 155.52 APE8-dihe-in -78.0, 73.69 APE8-rot-na 31.61 APE67-dihe-in -66.82, -5.75 -44.98, -49.24 APE12-dist-na 14.146 APE11-dist-na 9.329 APE10-dist-na 11.832 APE9-dist-in 6.88 None None None XRAY 2.8 0.245 0.286 B 335 261 41 0 0 3 [[589, 926]] 1.0 7khj TYR_KIT_HUMAN TYR 1.1e-104 355.4 1 261 261 809 810 811 813 815 623 640 644 789 791 790 792 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: WEG

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7KHJA

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 7KHJA P10721 566 931 976.0 WEG:61001 Type1 Active DFGin 6.611 13.898 BLAminus -132.69, -177.38 50.04, 76.8 -92.52, 23.6 290.02, 76.67 -56.27, -37.04 in-in in 7.663 Saltbr-in 3.294 HRD-in -79.35, -42.57 69.41, 10.19 in-in-in SNCiii in-in ActLoopNT-in 2.937 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.7, 141.7 APE9-dihe-in -138.2, 151.32 APE8-dihe-in -79.54, 72.69 APE8-rot-na 30.14 APE67-dihe-in -69.61, -6.54 -46.54, -51.48 APE12-dist-na 999.0 APE11-dist-na 8.404 APE10-dist-na 11.082 APE9-dist-in 6.956 None None None XRAY 2.8 0.245 0.286 A 335 288 20 0 0 2 [[589, 926]] 1.0 7khj Homo sapiens TYR_KIT_HUMAN TYR 1.1e-104 355.4 1 261 261 809 810 811 813 815 623 640 644 789 791 790 792 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7KHJB P10721 571 930 976.0 WEG:61001 Type1 Active DFGin 6.555 14.026 BLAminus -133.9, -173.37 50.96, 78.54 -96.13, 23.55 287.55, 72.9 -57.94, -35.66 in-in in 7.809 Saltbr-in 3.12 HRD-in -77.71, -37.21 66.91, 8.51 in-in-in SNCiii in-in ActLoopNT-in 3.022 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -98.94, 146.27 APE9-dihe-in -140.07, 155.52 APE8-dihe-in -78.0, 73.69 APE8-rot-na 31.61 APE67-dihe-in -66.82, -5.75 -44.98, -49.24 APE12-dist-na 14.146 APE11-dist-na 9.329 APE10-dist-na 11.832 APE9-dist-in 6.88 None None None XRAY 2.8 0.245 0.286 B 335 261 41 0 0 3 [[589, 926]] 1.0 7khj Homo sapiens TYR_KIT_HUMAN TYR 1.1e-104 355.4 1 261 261 809 810 811 813 815 623 640 644 789 791 790 792 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: WEG

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name