Ligand: VAR

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 3BHVA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 3BHVA P24941 1 298 298.0 VAR:60299 Type1 Active DFGin 6.749 15.036 BLAminus -132.56, 171.26 53.91, 86.13 -97.23, 18.97 284.34, 67.31 -58.53, -31.55 in-in in 8.469 Saltbr-in 2.954 HRD-in -79.43, -52.16 69.51, 13.01 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na 2.04, 123.28 APE9-dihe-na 76.77, 132.03 APE8-dihe-in -52.21, 130.26 APE8-rot-in 301.0 APE67-dihe-in -61.5, -22.12 -41.07, -48.88 APE12-dist-in 13.177 APE11-dist-in 9.389 APE10-dist-in 7.5 APE9-dist-in 3.276 None TPO160 TPO160 XRAY 2.1 0.184 0.229 A 300 296 2 0 0 0 [[4, 286]] 1.0 3bhv CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3BHVC P24941 1 296 298.0 VAR:60299 Type1 Active DFGin 6.717 15.117 BLAminus -131.34, 176.45 52.19, 85.58 -95.97, 17.71 279.3, 74.0 -62.28, -27.93 in-in in 8.469 Saltbr-in 2.832 HRD-in -77.61, -54.33 69.28, 11.28 in-in-in SNCiii in-in ActLoopNT-in 2.854 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na 34.08, 125.41 APE9-dihe-na 74.47, 123.34 APE8-dihe-in -47.68, 130.38 APE8-rot-in 303.56 APE67-dihe-in -62.09, -22.38 -41.46, -47.52 APE12-dist-in 12.813 APE11-dist-in 9.209 APE10-dist-in 7.16 APE9-dist-in 3.262 None TPO160 TPO160 XRAY 2.1 0.184 0.229 C 300 270 26 0 0 0 [[4, 286]] 1.0 3bhv CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: VAR

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 3BHVA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 3BHVA P24941 1 298 298.0 VAR:60299 Type1 Active DFGin 6.749 15.036 BLAminus -132.56, 171.26 53.91, 86.13 -97.23, 18.97 284.34, 67.31 -58.53, -31.55 in-in in 8.469 Saltbr-in 2.954 HRD-in -79.43, -52.16 69.51, 13.01 in-in-in SNCiii in-in ActLoopNT-in 2.912 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na 2.04, 123.28 APE9-dihe-na 76.77, 132.03 APE8-dihe-in -52.21, 130.26 APE8-rot-in 301.0 APE67-dihe-in -61.5, -22.12 -41.07, -48.88 APE12-dist-in 13.177 APE11-dist-in 9.389 APE10-dist-in 7.5 APE9-dist-in 3.276 None TPO160 TPO160 XRAY 2.1 0.184 0.229 A 300 296 2 0 0 0 [[4, 286]] 1.0 3bhv Homo sapiens CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3BHVC P24941 1 296 298.0 VAR:60299 Type1 Active DFGin 6.717 15.117 BLAminus -131.34, 176.45 52.19, 85.58 -95.97, 17.71 279.3, 74.0 -62.28, -27.93 in-in in 8.469 Saltbr-in 2.832 HRD-in -77.61, -54.33 69.28, 11.28 in-in-in SNCiii in-in ActLoopNT-in 2.854 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na 34.08, 125.41 APE9-dihe-na 74.47, 123.34 APE8-dihe-in -47.68, 130.38 APE8-rot-in 303.56 APE67-dihe-in -62.09, -22.38 -41.46, -47.52 APE12-dist-in 12.813 APE11-dist-in 9.209 APE10-dist-in 7.16 APE9-dist-in 3.262 None TPO160 TPO160 XRAY 2.1 0.184 0.229 C 300 270 26 0 0 0 [[4, 286]] 1.0 3bhv Homo sapiens CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: VAR

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name