Ligand: TT4

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

Ligand: TT4

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4XP2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_RAT 4XNEA P63086 9 354 358.0 TT4:401 Type1 Inactive DFGin 6.9062 16.5377 BLAminus -133.08, -178.31 62.87, 82.73 -101.62, 22.85 284.09, 79.92 -64.02, -26.26 out-out out 10.1683 Saltbr-out 6.631 HRD-in -73.52, -52.79 76.63, -2.65 out-in-out SNCoio in-out ActLoopNT-in 2.8538 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.86, -29.72 APE9-dihe-na -76.47, 164.24 APE8-dihe-in -60.32, 126.3 APE8-rot-in 310.6 APE67-dihe-in -64.56, -12.88 -50.2, -52.63 APE12-dist-out 14.3098 APE11-dist-in 11.1262 APE10-dist-in 7.0874 APE9-dist-in 4.4212 None None CME159,CME252 XRAY 1.8 0.18 0.218 A 346.0 346.0 0 31 31 0 [[23, 311]] 1.0 4xne Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.4 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_RAT 4XP2A P63086 8 353 358.0 TT4:401 Type1 Inactive DFGin 6.6105 16.3478 BLAminus -133.41, 176.73 60.84, 85.42 -101.78, 22.05 288.36, 75.74 -60.65, -27.7 in-in in 9.7181 Saltbr-in 2.5334 HRD-in -72.91, -49.95 73.33, 0.56 in-in-out SNCiio in-out ActLoopNT-in 2.758 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -113.44, -29.8 APE9-dihe-na -58.45, 157.07 APE8-dihe-in -60.02, 123.7 APE8-rot-in 308.55 APE67-dihe-in -60.45, -18.84 -52.73, -49.68 APE12-dist-out 14.4688 APE11-dist-in 11.2247 APE10-dist-in 7.4964 APE9-dist-in 4.1831 None None CME159,CME252 XRAY 1.748 0.187 0.226 A 351.0 339.0 0 31 31 0 [[23, 311]] 1.0 4xp2 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1

Ligand: TT4

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4XP2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_RAT 4XNEA P63086 9 354 358.0 TT4:401 Type1 Inactive DFGin 6.9062 16.5377 BLAminus -133.08, -178.31 62.87, 82.73 -101.62, 22.85 284.09, 79.92 -64.02, -26.26 out-out out 10.1683 Saltbr-out 6.631 HRD-in -73.52, -52.79 76.63, -2.65 out-in-out SNCoio in-out ActLoopNT-in 2.8538 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.86, -29.72 APE9-dihe-na -76.47, 164.24 APE8-dihe-in -60.32, 126.3 APE8-rot-in 310.6 APE67-dihe-in -64.56, -12.88 -50.2, -52.63 APE12-dist-out 14.3098 APE11-dist-in 11.1262 APE10-dist-in 7.0874 APE9-dist-in 4.4212 None None CME159,CME252 XRAY 1.8 0.18 0.218 A 346.0 346.0 0 31 31 0 [[23, 311]] 1.0 4xne Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.4 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_RAT 4XP2A P63086 8 353 358.0 TT4:401 Type1 Inactive DFGin 6.6105 16.3478 BLAminus -133.41, 176.73 60.84, 85.42 -101.78, 22.05 288.36, 75.74 -60.65, -27.7 in-in in 9.7181 Saltbr-in 2.5334 HRD-in -72.91, -49.95 73.33, 0.56 in-in-out SNCiio in-out ActLoopNT-in 2.758 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -113.44, -29.8 APE9-dihe-na -58.45, 157.07 APE8-dihe-in -60.02, 123.7 APE8-rot-in 308.55 APE67-dihe-in -60.45, -18.84 -52.73, -49.68 APE12-dist-out 14.4688 APE11-dist-in 11.2247 APE10-dist-in 7.4964 APE9-dist-in 4.1831 None None CME159,CME252 XRAY 1.748 0.187 0.226 A 351.0 339.0 0 31 31 0 [[23, 311]] 1.0 4xp2 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1