Ligand: T7Z

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4BCMC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 4BCMA P24941 1 296 298.0 T7Z:61297 Type1 Active DFGin 6.5188 15.3382 BLAminus -139.66, 174.2 58.72, 79.02 -93.6, 24.76 282.71, 70.29 -67.74, -29.26 in-in in 8.8258 Saltbr-in 2.8021 HRD-in -76.71, -53.42 71.43, 16.28 in-in-in SNCiii in-in ActLoopNT-in 2.8555 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.32, 150.29 APE9-dihe-na 79.09, 129.96 APE8-dihe-in -55.49, 136.02 APE8-rot-in 301.59 APE67-dihe-in -59.49, -23.97 -43.8, -51.06 APE12-dist-in 13.1922 APE11-dist-in 10.4094 APE10-dist-in 7.1915 APE9-dist-in 3.251 None TPO160 TPO160 XRAY 2.45 0.198 0.258 A 301.0 293.0 3 28 28 0 [[4, 286]] 1.0 4bcm CMGC_CDK2_HUMAN CMGC 6.6e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4BCMC P24941 1 294 298.0 T7Z:61295 Type1 Active DFGin 6.1946 15.2058 BLAminus -144.88, 174.61 58.31, 79.88 -94.05, 24.48 286.22, 64.67 -52.96, -36.75 in-in in 8.9292 Saltbr-in 2.868 HRD-in -78.72, -52.42 66.78, 17.05 in-in-in SNCiii in-in ActLoopNT-in 2.834 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -144.18, 152.85 APE9-dihe-na 70.08, 132.37 APE8-dihe-in -63.98, 114.75 APE8-rot-in 298.59 APE67-dihe-in -41.3, -28.08 -11.16, -73.96 APE12-dist-in 13.0788 APE11-dist-in 10.2273 APE10-dist-in 7.1356 APE9-dist-in 3.1813 None TPO160 TPO160 XRAY 2.45 0.198 0.258 C 301.0 294.0 0 28 28 0 [[4, 286]] 1.0 4bcm CMGC_CDK2_HUMAN CMGC 6.6e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK9 CDK9_HUMAN 4BCHA P50750 7 327 372.0 T7Z:1328 Type1 Inactive DFGin 7.0222 15.2506 BLAminus -131.52, 173.1 62.62, 79.06 -97.34, 18.94 284.72, 72.84 -65.45, -18.12 in-out in 9.5639 Saltbr-out 4.3367 HRD-in -78.74, -44.37 68.53, 5.43 out-in-in SNCoii in-in ActLoopNT-in 2.9166 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.64, 156.76 APE9-dihe-na 81.03, 133.91 APE8-dihe-in -51.15, 142.4 APE8-rot-in 295.91 APE67-dihe-in -66.84, -22.68 -48.59, -47.41 APE12-dist-in 13.2669 APE11-dist-in 10.899 APE10-dist-in 6.9125 APE9-dist-in 3.1811 None TPO186 TPO186 XRAY 2.958 0.169 0.21 A 331.0 309.0 12 32 27 5 [[19, 315]] 1.0 4bch CMGC_CDK9_HUMAN CMGC 4.1e-80 275.1 1.0 301.0 301.0 166 167 168 170 172 48 66 70 146 148 147 149.0 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9

Ligand: T7Z

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4BCMC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 4BCMA P24941 1 296 298.0 T7Z:61297 Type1 Active DFGin 6.5188 15.3382 BLAminus -139.66, 174.2 58.72, 79.02 -93.6, 24.76 282.71, 70.29 -67.74, -29.26 in-in in 8.8258 Saltbr-in 2.8021 HRD-in -76.71, -53.42 71.43, 16.28 in-in-in SNCiii in-in ActLoopNT-in 2.8555 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.32, 150.29 APE9-dihe-na 79.09, 129.96 APE8-dihe-in -55.49, 136.02 APE8-rot-in 301.59 APE67-dihe-in -59.49, -23.97 -43.8, -51.06 APE12-dist-in 13.1922 APE11-dist-in 10.4094 APE10-dist-in 7.1915 APE9-dist-in 3.251 None TPO160 TPO160 XRAY 2.45 0.198 0.258 A 301.0 293.0 3 28 28 0 [[4, 286]] 1.0 4bcm Homo sapiens CMGC_CDK2_HUMAN CMGC 6.6e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4BCMC P24941 1 294 298.0 T7Z:61295 Type1 Active DFGin 6.1946 15.2058 BLAminus -144.88, 174.61 58.31, 79.88 -94.05, 24.48 286.22, 64.67 -52.96, -36.75 in-in in 8.9292 Saltbr-in 2.868 HRD-in -78.72, -52.42 66.78, 17.05 in-in-in SNCiii in-in ActLoopNT-in 2.834 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -144.18, 152.85 APE9-dihe-na 70.08, 132.37 APE8-dihe-in -63.98, 114.75 APE8-rot-in 298.59 APE67-dihe-in -41.3, -28.08 -11.16, -73.96 APE12-dist-in 13.0788 APE11-dist-in 10.2273 APE10-dist-in 7.1356 APE9-dist-in 3.1813 None TPO160 TPO160 XRAY 2.45 0.198 0.258 C 301.0 294.0 0 28 28 0 [[4, 286]] 1.0 4bcm Homo sapiens CMGC_CDK2_HUMAN CMGC 6.6e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK9 CDK9_HUMAN 4BCHA P50750 7 327 372.0 T7Z:1328 Type1 Inactive DFGin 7.0222 15.2506 BLAminus -131.52, 173.1 62.62, 79.06 -97.34, 18.94 284.72, 72.84 -65.45, -18.12 in-out in 9.5639 Saltbr-out 4.3367 HRD-in -78.74, -44.37 68.53, 5.43 out-in-in SNCoii in-in ActLoopNT-in 2.9166 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.64, 156.76 APE9-dihe-na 81.03, 133.91 APE8-dihe-in -51.15, 142.4 APE8-rot-in 295.91 APE67-dihe-in -66.84, -22.68 -48.59, -47.41 APE12-dist-in 13.2669 APE11-dist-in 10.899 APE10-dist-in 6.9125 APE9-dist-in 3.1811 None TPO186 TPO186 XRAY 2.958 0.169 0.21 A 331.0 309.0 12 32 27 5 [[19, 315]] 1.0 4bch Homo sapiens CMGC_CDK9_HUMAN CMGC 4.1e-80 275.1 1.0 301.0 301.0 166 167 168 170 172 48 66 70 146 148 147 149.0 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9

Ligand: T7Z

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name