Ligand: T6Q

Total number of chains: 3
Active chains: 3
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4BCOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 4BCOA P24941 1 298 298.0 T6Q:61299 Type1 Active DFGin 6.4743 15.1168 BLAminus -135.79, 171.97 56.93, 82.69 -96.39, 24.73 280.25, 67.27 -60.9, -26.66 in-in in 8.4924 Saltbr-in 2.6429 HRD-in -81.64, -50.15 69.2, 12.85 in-in-in SNCiii in-in ActLoopNT-in 2.985 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.17, 153.87 APE9-dihe-na 75.41, 126.9 APE8-dihe-in -55.82, 131.29 APE8-rot-in 296.78 APE67-dihe-in -57.59, -24.46 -39.45, -52.38 APE12-dist-in 13.0076 APE11-dist-in 10.2544 APE10-dist-in 7.069 APE9-dist-in 3.1788 None TPO160 TPO160 XRAY 2.05 0.191 0.226 A 300.0 298.0 0 28 28 0 [[4, 286]] 1.0 4bco CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4BCOC P24941 1 296 298.0 T6Q:61298 Type1 Active DFGin 6.3664 15.1693 BLAminus -138.07, 175.97 55.78, 82.31 -98.44, 30.3 281.46, 70.87 -70.2, -23.66 in-in in 8.6805 Saltbr-in 2.7089 HRD-in -83.59, -54.01 73.46, 6.77 in-in-in SNCiii in-in ActLoopNT-in 3.0095 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.63, 154.6 APE9-dihe-na 71.04, 127.33 APE8-dihe-in -59.71, 136.46 APE8-rot-in 300.15 APE67-dihe-in -53.39, -26.5 -38.01, -58.97 APE12-dist-in 12.8026 APE11-dist-in 9.8885 APE10-dist-in 6.9161 APE9-dist-in 3.1423 None TPO160 TPO160 XRAY 2.05 0.191 0.226 C 300.0 269.0 27 28 28 0 [[4, 286]] 1.0 4bco CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK9 CDK9_HUMAN 4BCFA P50750 6 326 372.0 T6Q:1327 Type1 Active DFGin 7.0353 15.0056 BLAminus -130.89, 175.85 58.26, 78.19 -93.84, 20.92 284.01, 74.28 -69.0, -18.91 in-in in 9.3848 Saltbr-in 3.4539 HRD-in -78.09, -44.7 68.67, 6.76 in-in-in SNCiii in-in ActLoopNT-in 2.8709 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.92, 149.94 APE9-dihe-na 81.04, 132.5 APE8-dihe-in -49.66, 140.73 APE8-rot-in 291.42 APE67-dihe-in -67.27, -22.18 -50.7, -44.79 APE12-dist-in 13.1043 APE11-dist-in 10.3036 APE10-dist-in 6.9066 APE9-dist-in 3.1282 None TPO186 TPO186 XRAY 3.011 0.169 0.224 A 331.0 308.0 13 32 27 5 [[19, 315]] 1.0 4bcf CMGC_CDK9_HUMAN CMGC 3.7e-80 275.2 1.0 301.0 301.0 166 167 168 170 172 48 66 70 146 148 147 149.0 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9

Ligand: T6Q

Total number of chains: 3
Active chains: 3
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4BCOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 4BCOA P24941 1 298 298.0 T6Q:61299 Type1 Active DFGin 6.4743 15.1168 BLAminus -135.79, 171.97 56.93, 82.69 -96.39, 24.73 280.25, 67.27 -60.9, -26.66 in-in in 8.4924 Saltbr-in 2.6429 HRD-in -81.64, -50.15 69.2, 12.85 in-in-in SNCiii in-in ActLoopNT-in 2.985 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.17, 153.87 APE9-dihe-na 75.41, 126.9 APE8-dihe-in -55.82, 131.29 APE8-rot-in 296.78 APE67-dihe-in -57.59, -24.46 -39.45, -52.38 APE12-dist-in 13.0076 APE11-dist-in 10.2544 APE10-dist-in 7.069 APE9-dist-in 3.1788 None TPO160 TPO160 XRAY 2.05 0.191 0.226 A 300.0 298.0 0 28 28 0 [[4, 286]] 1.0 4bco Homo sapiens CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4BCOC P24941 1 296 298.0 T6Q:61298 Type1 Active DFGin 6.3664 15.1693 BLAminus -138.07, 175.97 55.78, 82.31 -98.44, 30.3 281.46, 70.87 -70.2, -23.66 in-in in 8.6805 Saltbr-in 2.7089 HRD-in -83.59, -54.01 73.46, 6.77 in-in-in SNCiii in-in ActLoopNT-in 3.0095 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.63, 154.6 APE9-dihe-na 71.04, 127.33 APE8-dihe-in -59.71, 136.46 APE8-rot-in 300.15 APE67-dihe-in -53.39, -26.5 -38.01, -58.97 APE12-dist-in 12.8026 APE11-dist-in 9.8885 APE10-dist-in 6.9161 APE9-dist-in 3.1423 None TPO160 TPO160 XRAY 2.05 0.191 0.226 C 300.0 269.0 27 28 28 0 [[4, 286]] 1.0 4bco Homo sapiens CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK9 CDK9_HUMAN 4BCFA P50750 6 326 372.0 T6Q:1327 Type1 Active DFGin 7.0353 15.0056 BLAminus -130.89, 175.85 58.26, 78.19 -93.84, 20.92 284.01, 74.28 -69.0, -18.91 in-in in 9.3848 Saltbr-in 3.4539 HRD-in -78.09, -44.7 68.67, 6.76 in-in-in SNCiii in-in ActLoopNT-in 2.8709 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.92, 149.94 APE9-dihe-na 81.04, 132.5 APE8-dihe-in -49.66, 140.73 APE8-rot-in 291.42 APE67-dihe-in -67.27, -22.18 -50.7, -44.79 APE12-dist-in 13.1043 APE11-dist-in 10.3036 APE10-dist-in 6.9066 APE9-dist-in 3.1282 None TPO186 TPO186 XRAY 3.011 0.169 0.224 A 331.0 308.0 13 32 27 5 [[19, 315]] 1.0 4bcf Homo sapiens CMGC_CDK9_HUMAN CMGC 3.7e-80 275.2 1.0 301.0 301.0 166 167 168 170 172 48 66 70 146 148 147 149.0 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9

Ligand: T6Q

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name