Ligand: T5G

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ET5A
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ET5A P24941 1 294 298.0 T5G:60501,T5G:60503 Type1,Allosteric Active DFGin 6.678 15.291 BLAminus -137.17, 178.34 60.51, 85.6 -108.17, 31.01 281.27, 78.69 -80.57, -23.43 in-in in 8.726 Saltbr-in 2.905 HRD-in -80.11, -56.4 77.63, 19.45 in-in-in SNCiii in-in ActLoopNT-in 2.99 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.95, 140.76 APE9-dihe-na 77.59, 129.77 APE8-dihe-in -58.29, 133.79 APE8-rot-in 288.36 APE67-dihe-in -61.58, -15.9 -39.95, -50.82 APE12-dist-in 12.774 APE11-dist-in 9.662 APE10-dist-in 7.134 APE9-dist-in 3.396 None TPO160 TPO160 XRAY 2.53 0.201 0.221 A 302 294 0 0 0 0 [[4, 286]] 1.0 9et5 CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ET5C P24941 1 296 298.0 T5G:60501,T5G:60502 Type1,Allosteric Active DFGin 6.662 15.494 BLAminus -134.15, -179.13 56.52, 75.78 -94.35, 30.58 280.05, 68.52 -72.1, -25.78 in-in in 8.742 Saltbr-in 2.669 HRD-in -82.99, -55.97 71.28, 11.54 in-in-in SNCiii in-in ActLoopNT-in 2.839 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.03, 145.44 APE9-dihe-na 80.72, 131.2 APE8-dihe-in -58.76, 142.02 APE8-rot-in 303.79 APE67-dihe-in -55.68, -24.95 -43.97, -53.66 APE12-dist-in 12.765 APE11-dist-in 10.549 APE10-dist-in 6.832 APE9-dist-in 3.271 None TPO160 TPO160 XRAY 2.53 0.201 0.221 C 302 296 0 0 0 0 [[4, 286]] 1.0 9et5 CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: T5G

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ET5A
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ET5A P24941 1 294 298.0 T5G:60501,T5G:60503 Type1,Allosteric Active DFGin 6.678 15.291 BLAminus -137.17, 178.34 60.51, 85.6 -108.17, 31.01 281.27, 78.69 -80.57, -23.43 in-in in 8.726 Saltbr-in 2.905 HRD-in -80.11, -56.4 77.63, 19.45 in-in-in SNCiii in-in ActLoopNT-in 2.99 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.95, 140.76 APE9-dihe-na 77.59, 129.77 APE8-dihe-in -58.29, 133.79 APE8-rot-in 288.36 APE67-dihe-in -61.58, -15.9 -39.95, -50.82 APE12-dist-in 12.774 APE11-dist-in 9.662 APE10-dist-in 7.134 APE9-dist-in 3.396 None TPO160 TPO160 XRAY 2.53 0.201 0.221 A 302 294 0 0 0 0 [[4, 286]] 1.0 9et5 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ET5C P24941 1 296 298.0 T5G:60501,T5G:60502 Type1,Allosteric Active DFGin 6.662 15.494 BLAminus -134.15, -179.13 56.52, 75.78 -94.35, 30.58 280.05, 68.52 -72.1, -25.78 in-in in 8.742 Saltbr-in 2.669 HRD-in -82.99, -55.97 71.28, 11.54 in-in-in SNCiii in-in ActLoopNT-in 2.839 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.03, 145.44 APE9-dihe-na 80.72, 131.2 APE8-dihe-in -58.76, 142.02 APE8-rot-in 303.79 APE67-dihe-in -55.68, -24.95 -43.97, -53.66 APE12-dist-in 12.765 APE11-dist-in 10.549 APE10-dist-in 6.832 APE9-dist-in 3.271 None TPO160 TPO160 XRAY 2.53 0.201 0.221 C 302 296 0 0 0 0 [[4, 286]] 1.0 9et5 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: T5G

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name