Ligand: SY4

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 9IHIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 9HYHA P68400 2 333 391.0 SY4:401,3NG:402 Allosteric,Type1 Inactive DFGin 7.4771 16.3937 BLAminus -121.68, -179.33 58.66, 73.4 -93.07, 20.44 296.95, 80.12 -72.1, -13.43 in-in in 9.5519 Saltbr-in 2.7053 HRD-in -71.8, -47.17 67.87, 7.84 in-in-out SNCiio in-out ActLoopNT-in 2.9381 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.17, 164.17 APE9-dihe-na 70.19, 157.91 APE8-dihe-in -73.34, 145.8 APE8-rot-out 156.95 APE67-dihe-in -65.82, -17.6 -47.03, -48.02 APE12-dist-in 12.6264 APE11-dist-in 10.464 APE10-dist-in 6.1328 APE9-dist-in 3.3684 None None None XRAY 1.96 0.201 0.241 A 355.0 332.0 0 27 27 0 [[39, 324]] 1.0 9hyh CMGC_CSNK2A1_HUMAN CMGC 1.6e-69 240.3 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9HYHB P68400 2 332 391.0 3NG:401,SY4:402 Type1,Allosteric Inactive DFGin 7.4554 16.6858 BLAminus -121.17, -179.71 60.15, 74.28 -94.36, 20.01 295.53, 80.91 -72.98, -14.61 in-in in 9.7479 Saltbr-in 2.8021 HRD-in -73.27, -48.07 68.78, 4.9 in-in-out SNCiio in-out ActLoopNT-in 2.8873 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.73, 163.63 APE9-dihe-na 71.35, 156.53 APE8-dihe-in -76.0, 150.02 APE8-rot-out 60.35 APE67-dihe-in -68.11, -15.2 -46.02, -50.6 APE12-dist-in 12.7487 APE11-dist-in 10.8432 APE10-dist-in 6.3197 APE9-dist-in 3.734 None None None XRAY 1.96 0.201 0.241 B 355.0 331.0 0 27 27 0 [[39, 324]] 1.0 9hyh CMGC_CSNK2A1_HUMAN CMGC 1.6e-69 240.3 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 9IHIA P19784 7 333 350.0 SY4:401,3NG:402 Allosteric,Type1 Inactive DFGin 7.4146 16.0263 BLAminus -114.42, 178.99 58.97, 77.48 -92.68, 17.89 295.72, 83.62 -70.78, -17.6 in-in in 9.1661 Saltbr-in 2.8146 HRD-in -75.11, -48.36 72.21, 10.05 in-in-out SNCiio in-out ActLoopNT-in 2.8415 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.76, 169.32 APE9-dihe-na 65.88, 158.62 APE8-dihe-in -76.33, 145.23 APE8-rot-out 154.92 APE67-dihe-in -68.36, -16.5 -40.48, -52.03 APE12-dist-in 12.7831 APE11-dist-in 10.5056 APE10-dist-in 6.283 APE9-dist-in 3.2357 C336S None None XRAY 1.23 0.136 0.166 A 370.0 327.0 0 27 27 0 [[40, 325]] 1.0 9ihi CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1.0 301.0 301.0 175 176 177 179 181 69 82 86 154 156 155 157.0 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

Ligand: SY4

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 9IHIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 9HYHA P68400 2 333 391.0 SY4:401,3NG:402 Allosteric,Type1 Inactive DFGin 7.4771 16.3937 BLAminus -121.68, -179.33 58.66, 73.4 -93.07, 20.44 296.95, 80.12 -72.1, -13.43 in-in in 9.5519 Saltbr-in 2.7053 HRD-in -71.8, -47.17 67.87, 7.84 in-in-out SNCiio in-out ActLoopNT-in 2.9381 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.17, 164.17 APE9-dihe-na 70.19, 157.91 APE8-dihe-in -73.34, 145.8 APE8-rot-out 156.95 APE67-dihe-in -65.82, -17.6 -47.03, -48.02 APE12-dist-in 12.6264 APE11-dist-in 10.464 APE10-dist-in 6.1328 APE9-dist-in 3.3684 None None None XRAY 1.96 0.201 0.241 A 355.0 332.0 0 27 27 0 [[39, 324]] 1.0 9hyh Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.6e-69 240.3 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9HYHB P68400 2 332 391.0 3NG:401,SY4:402 Type1,Allosteric Inactive DFGin 7.4554 16.6858 BLAminus -121.17, -179.71 60.15, 74.28 -94.36, 20.01 295.53, 80.91 -72.98, -14.61 in-in in 9.7479 Saltbr-in 2.8021 HRD-in -73.27, -48.07 68.78, 4.9 in-in-out SNCiio in-out ActLoopNT-in 2.8873 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.73, 163.63 APE9-dihe-na 71.35, 156.53 APE8-dihe-in -76.0, 150.02 APE8-rot-out 60.35 APE67-dihe-in -68.11, -15.2 -46.02, -50.6 APE12-dist-in 12.7487 APE11-dist-in 10.8432 APE10-dist-in 6.3197 APE9-dist-in 3.734 None None None XRAY 1.96 0.201 0.241 B 355.0 331.0 0 27 27 0 [[39, 324]] 1.0 9hyh Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.6e-69 240.3 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 9IHIA P19784 7 333 350.0 SY4:401,3NG:402 Allosteric,Type1 Inactive DFGin 7.4146 16.0263 BLAminus -114.42, 178.99 58.97, 77.48 -92.68, 17.89 295.72, 83.62 -70.78, -17.6 in-in in 9.1661 Saltbr-in 2.8146 HRD-in -75.11, -48.36 72.21, 10.05 in-in-out SNCiio in-out ActLoopNT-in 2.8415 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.76, 169.32 APE9-dihe-na 65.88, 158.62 APE8-dihe-in -76.33, 145.23 APE8-rot-out 154.92 APE67-dihe-in -68.36, -16.5 -40.48, -52.03 APE12-dist-in 12.7831 APE11-dist-in 10.5056 APE10-dist-in 6.283 APE9-dist-in 3.2357 C336S None None XRAY 1.23 0.136 0.166 A 370.0 327.0 0 27 27 0 [[40, 325]] 1.0 9ihi Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1.1e-69 240.9 1.0 301.0 301.0 175 176 177 179 181 69 82 86 154 156 155 157.0 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

Ligand: SY4

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name