Ligand: RKK

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7AJVA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7AJVA Q13627 148 481 763.0 RKK:60501 Type1 Inactive DFGin 7.083 14.724 BLAminus -123.61, 170.03 70.85, 87.15 -98.76, 25.47 292.1, 75.69 -58.41, -34.3 in-in in 8.669 Saltbr-in 2.489 HRD-in -60.17, -50.82 77.68, 3.17 in-in-out SNCiio in-out ActLoopNT-in 2.961 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -138.87, 159.47 APE9-dihe-na 70.75, 141.67 APE8-dihe-in -65.64, 133.79 APE8-rot-out 171.55 APE67-dihe-in -58.95, -30.68 -50.41, -48.06 APE12-dist-in 11.625 APE11-dist-in 10.455 APE10-dist-in 6.904 APE9-dist-in 3.063 None PTR321 PTR321 XRAY 2.1 0.182 0.219 A 359 330 4 0 0 0 [[159, 479]] 1.0 7ajv CMGC_DYRK1A_HUMAN CMGC 8.2e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7AJVB Q13627 148 481 763.0 RKK:60501 Type1 Inactive DFGin 7.184 14.628 BLAminus -117.14, 169.86 69.68, 90.8 -103.92, 27.7 282.23, 78.07 -72.14, -22.36 in-in in 8.618 Saltbr-in 2.757 HRD-in -62.69, -52.71 75.84, 3.99 in-in-out SNCiio in-out ActLoopNT-in 2.797 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -148.21, 169.45 APE9-dihe-na 77.96, 139.9 APE8-dihe-in -73.65, 144.05 APE8-rot-out 83.51 APE67-dihe-in -59.27, -27.74 -53.72, -47.01 APE12-dist-in 12.782 APE11-dist-in 10.832 APE10-dist-in 6.539 APE9-dist-in 3.096 None PTR321 PTR321 XRAY 2.1 0.182 0.219 B 359 327 7 0 0 0 [[159, 479]] 1.0 7ajv CMGC_DYRK1A_HUMAN CMGC 8.2e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: RKK

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7AJVA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7AJVA Q13627 148 481 763.0 RKK:60501 Type1 Inactive DFGin 7.083 14.724 BLAminus -123.61, 170.03 70.85, 87.15 -98.76, 25.47 292.1, 75.69 -58.41, -34.3 in-in in 8.669 Saltbr-in 2.489 HRD-in -60.17, -50.82 77.68, 3.17 in-in-out SNCiio in-out ActLoopNT-in 2.961 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -138.87, 159.47 APE9-dihe-na 70.75, 141.67 APE8-dihe-in -65.64, 133.79 APE8-rot-out 171.55 APE67-dihe-in -58.95, -30.68 -50.41, -48.06 APE12-dist-in 11.625 APE11-dist-in 10.455 APE10-dist-in 6.904 APE9-dist-in 3.063 None PTR321 PTR321 XRAY 2.1 0.182 0.219 A 359 330 4 0 0 0 [[159, 479]] 1.0 7ajv Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.2e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7AJVB Q13627 148 481 763.0 RKK:60501 Type1 Inactive DFGin 7.184 14.628 BLAminus -117.14, 169.86 69.68, 90.8 -103.92, 27.7 282.23, 78.07 -72.14, -22.36 in-in in 8.618 Saltbr-in 2.757 HRD-in -62.69, -52.71 75.84, 3.99 in-in-out SNCiio in-out ActLoopNT-in 2.797 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -148.21, 169.45 APE9-dihe-na 77.96, 139.9 APE8-dihe-in -73.65, 144.05 APE8-rot-out 83.51 APE67-dihe-in -59.27, -27.74 -53.72, -47.01 APE12-dist-in 12.782 APE11-dist-in 10.832 APE10-dist-in 6.539 APE9-dist-in 3.096 None PTR321 PTR321 XRAY 2.1 0.182 0.219 B 359 327 7 0 0 0 [[159, 479]] 1.0 7ajv Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.2e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: RKK

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name