Ligand: RJZ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7AKBB
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7AKBA Q13627 148 481 763.0 RJZ:60501 Type1 Inactive DFGin 7.213 14.196 BLAminus -124.09, -178.78 64.16, 81.03 -98.47, 34.82 287.29, 82.14 -91.53, -10.23 in-in in 8.413 Saltbr-in 2.371 HRD-in -60.25, -38.91 64.29, 1.37 in-in-out SNCiio in-out ActLoopNT-in 2.689 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -129.85, 174.48 APE9-dihe-na 78.85, 161.11 APE8-dihe-in -81.8, 138.37 APE8-rot-out 193.17 APE67-dihe-in -52.47, -29.53 -48.51, -57.21 APE12-dist-in 12.559 APE11-dist-in 10.708 APE10-dist-in 6.026 APE9-dist-in 2.937 None PTR321 PTR321 XRAY 2.8 0.197 0.248 A 359 327 7 0 0 0 [[159, 479]] 1.0 7akb CMGC_DYRK1A_HUMAN CMGC 8.2e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7AKBB Q13627 148 481 763.0 RJZ:60501 Type1 Inactive DFGin 7.114 14.481 BLAminus -126.85, -177.09 63.55, 78.5 -99.69, 38.47 289.46, 82.22 -88.73, -23.7 in-in in 8.506 Saltbr-in 2.46 HRD-in -57.16, -39.4 67.41, 4.61 in-in-out SNCiio in-out ActLoopNT-in 2.895 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -116.81, 161.1 APE9-dihe-na 75.42, 163.85 APE8-dihe-in -80.4, 143.9 APE8-rot-out 185.64 APE67-dihe-in -56.87, -37.37 -45.64, -60.47 APE12-dist-in 11.599 APE11-dist-in 10.648 APE10-dist-in 6.659 APE9-dist-in 2.962 None PTR321 PTR321 XRAY 2.8 0.197 0.248 B 359 329 5 0 0 0 [[159, 479]] 1.0 7akb CMGC_DYRK1A_HUMAN CMGC 8.2e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: RJZ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7AKBB
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7AKBA Q13627 148 481 763.0 RJZ:60501 Type1 Inactive DFGin 7.213 14.196 BLAminus -124.09, -178.78 64.16, 81.03 -98.47, 34.82 287.29, 82.14 -91.53, -10.23 in-in in 8.413 Saltbr-in 2.371 HRD-in -60.25, -38.91 64.29, 1.37 in-in-out SNCiio in-out ActLoopNT-in 2.689 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -129.85, 174.48 APE9-dihe-na 78.85, 161.11 APE8-dihe-in -81.8, 138.37 APE8-rot-out 193.17 APE67-dihe-in -52.47, -29.53 -48.51, -57.21 APE12-dist-in 12.559 APE11-dist-in 10.708 APE10-dist-in 6.026 APE9-dist-in 2.937 None PTR321 PTR321 XRAY 2.8 0.197 0.248 A 359 327 7 0 0 0 [[159, 479]] 1.0 7akb Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.2e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7AKBB Q13627 148 481 763.0 RJZ:60501 Type1 Inactive DFGin 7.114 14.481 BLAminus -126.85, -177.09 63.55, 78.5 -99.69, 38.47 289.46, 82.22 -88.73, -23.7 in-in in 8.506 Saltbr-in 2.46 HRD-in -57.16, -39.4 67.41, 4.61 in-in-out SNCiio in-out ActLoopNT-in 2.895 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -116.81, 161.1 APE9-dihe-na 75.42, 163.85 APE8-dihe-in -80.4, 143.9 APE8-rot-out 185.64 APE67-dihe-in -56.87, -37.37 -45.64, -60.47 APE12-dist-in 11.599 APE11-dist-in 10.648 APE10-dist-in 6.659 APE9-dist-in 2.962 None PTR321 PTR321 XRAY 2.8 0.197 0.248 B 359 329 5 0 0 0 [[159, 479]] 1.0 7akb Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.2e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: RJZ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name