Ligand: R7O

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8C3RA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 8C3RA Q13627 135 480 763.0 R7O:501 Type1 Active DFGin 7.582 14.765 BLAminus -123.3, 160.97 61.95, 92.11 -99.77, 29.64 287.05, 71.45 -70.47, -16.78 in-in in 8.52 Saltbr-in 2.774 HRD-in -65.6, -46.48 78.0, 2.34 in-in-in SNCiii in-in ActLoopNT-in 2.763 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -118.35, 171.73 APE9-dihe-na 71.24, 149.33 APE8-dihe-in -74.45, 145.43 APE8-rot-in 300.61 APE67-dihe-in -59.08, -27.8 -56.43, -44.81 APE12-dist-in 12.402 APE11-dist-in 11.201 APE10-dist-in 7.222 APE9-dist-in 3.222 None PTR321 PTR321 XRAY 2.06 0.187 0.209 A 370 346 0 0 0 0 [[159, 479]] 1.0 8c3r CMGC_DYRK1A_HUMAN CMGC 9.2e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 8C3RB Q13627 136 480 763.0 R7O:501 Type1 Active DFGin 7.136 14.811 BLAminus -123.29, 167.45 65.44, 80.19 -97.63, 28.79 287.96, 74.69 -68.15, -22.5 in-in in 8.662 Saltbr-in 2.942 HRD-in -67.34, -39.55 70.0, 7.08 in-in-in SNCiii in-in ActLoopNT-in 2.703 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.04, 166.27 APE9-dihe-na 72.62, 139.21 APE8-dihe-in -62.23, 144.37 APE8-rot-in 295.1 APE67-dihe-in -57.99, -27.22 -56.76, -45.19 APE12-dist-in 12.555 APE11-dist-in 10.994 APE10-dist-in 7.329 APE9-dist-in 3.225 None PTR321 PTR321 XRAY 2.06 0.187 0.209 B 370 345 0 0 0 0 [[159, 479]] 1.0 8c3r CMGC_DYRK1A_HUMAN CMGC 9.2e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: R7O

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8C3RA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 8C3RA Q13627 135 480 763.0 R7O:501 Type1 Active DFGin 7.582 14.765 BLAminus -123.3, 160.97 61.95, 92.11 -99.77, 29.64 287.05, 71.45 -70.47, -16.78 in-in in 8.52 Saltbr-in 2.774 HRD-in -65.6, -46.48 78.0, 2.34 in-in-in SNCiii in-in ActLoopNT-in 2.763 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -118.35, 171.73 APE9-dihe-na 71.24, 149.33 APE8-dihe-in -74.45, 145.43 APE8-rot-in 300.61 APE67-dihe-in -59.08, -27.8 -56.43, -44.81 APE12-dist-in 12.402 APE11-dist-in 11.201 APE10-dist-in 7.222 APE9-dist-in 3.222 None PTR321 PTR321 XRAY 2.06 0.187 0.209 A 370 346 0 0 0 0 [[159, 479]] 1.0 8c3r Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9.2e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 8C3RB Q13627 136 480 763.0 R7O:501 Type1 Active DFGin 7.136 14.811 BLAminus -123.29, 167.45 65.44, 80.19 -97.63, 28.79 287.96, 74.69 -68.15, -22.5 in-in in 8.662 Saltbr-in 2.942 HRD-in -67.34, -39.55 70.0, 7.08 in-in-in SNCiii in-in ActLoopNT-in 2.703 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.04, 166.27 APE9-dihe-na 72.62, 139.21 APE8-dihe-in -62.23, 144.37 APE8-rot-in 295.1 APE67-dihe-in -57.99, -27.22 -56.76, -45.19 APE12-dist-in 12.555 APE11-dist-in 10.994 APE10-dist-in 7.329 APE9-dist-in 3.225 None PTR321 PTR321 XRAY 2.06 0.187 0.209 B 370 345 0 0 0 0 [[159, 479]] 1.0 8c3r Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9.2e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: R7O

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name