Ligand: R7B

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7ACKA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 7ACKA P24941 1 294 298.0 R7B:60301 Type1 Active DFGin 6.6 15.093 BLAminus -137.07, 176.76 54.39, 79.26 -91.38, 21.84 284.28, 68.95 -64.22, -25.1 in-in in 8.363 Saltbr-in 2.815 HRD-in -78.41, -53.61 67.74, 12.29 in-in-in SNCiii in-in ActLoopNT-in 3.065 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.72, 155.75 APE9-dihe-na 71.06, 135.17 APE8-dihe-in -61.37, 135.3 APE8-rot-in 300.54 APE67-dihe-in -61.15, -26.3 -45.36, -47.78 APE12-dist-in 12.888 APE11-dist-in 10.064 APE10-dist-in 6.79 APE9-dist-in 3.167 None TPO160 TPO160 XRAY 1.8 0.197 0.232 A 299 294 0 0 0 0 [[4, 286]] 1.0 7ack CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7ACKC P24941 1 294 298.0 R7B:60301 Type1 Active DFGin 6.644 15.137 BLAminus -134.26, 175.58 54.35, 80.24 -91.1, 18.3 281.67, 67.12 -62.1, -23.73 in-in in 8.426 Saltbr-in 2.768 HRD-in -86.24, -55.68 72.18, 14.84 in-in-in SNCiii in-in ActLoopNT-in 3.037 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.93, 155.94 APE9-dihe-na 74.79, 129.29 APE8-dihe-in -59.07, 138.14 APE8-rot-in 303.31 APE67-dihe-in -58.22, -26.49 -46.93, -50.39 APE12-dist-in 12.846 APE11-dist-in 10.021 APE10-dist-in 6.74 APE9-dist-in 3.244 None TPO160 TPO160 XRAY 1.8 0.197 0.232 C 299 294 0 0 0 0 [[4, 286]] 1.0 7ack CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: R7B

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7ACKA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 7ACKA P24941 1 294 298.0 R7B:60301 Type1 Active DFGin 6.6 15.093 BLAminus -137.07, 176.76 54.39, 79.26 -91.38, 21.84 284.28, 68.95 -64.22, -25.1 in-in in 8.363 Saltbr-in 2.815 HRD-in -78.41, -53.61 67.74, 12.29 in-in-in SNCiii in-in ActLoopNT-in 3.065 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.72, 155.75 APE9-dihe-na 71.06, 135.17 APE8-dihe-in -61.37, 135.3 APE8-rot-in 300.54 APE67-dihe-in -61.15, -26.3 -45.36, -47.78 APE12-dist-in 12.888 APE11-dist-in 10.064 APE10-dist-in 6.79 APE9-dist-in 3.167 None TPO160 TPO160 XRAY 1.8 0.197 0.232 A 299 294 0 0 0 0 [[4, 286]] 1.0 7ack Homo sapiens CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7ACKC P24941 1 294 298.0 R7B:60301 Type1 Active DFGin 6.644 15.137 BLAminus -134.26, 175.58 54.35, 80.24 -91.1, 18.3 281.67, 67.12 -62.1, -23.73 in-in in 8.426 Saltbr-in 2.768 HRD-in -86.24, -55.68 72.18, 14.84 in-in-in SNCiii in-in ActLoopNT-in 3.037 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.93, 155.94 APE9-dihe-na 74.79, 129.29 APE8-dihe-in -59.07, 138.14 APE8-rot-in 303.31 APE67-dihe-in -58.22, -26.49 -46.93, -50.39 APE12-dist-in 12.846 APE11-dist-in 10.021 APE10-dist-in 6.74 APE9-dist-in 3.244 None TPO160 TPO160 XRAY 1.8 0.197 0.232 C 299 294 0 0 0 0 [[4, 286]] 1.0 7ack Homo sapiens CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: R7B

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name