Ligand: QQ2

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2IW6C
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2IW6A P24941 1 295 298.0 QQ2:61296 Type1 Active DFGin 6.763 15.33 BLAminus -137.04, -179.89 52.44, 77.16 -90.65, 20.03 286.27, 71.9 -65.55, -20.57 in-in in 8.498 Saltbr-in 3.28 HRD-in -76.04, -56.62 74.08, 13.78 in-in-in SNCiii in-in ActLoopNT-in 2.792 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.81, 140.32 APE9-dihe-na 81.92, 120.48 APE8-dihe-in -44.7, 124.8 APE8-rot-in 298.42 APE67-dihe-in -65.53, -21.14 -40.4, -43.63 APE12-dist-in 13.164 APE11-dist-in 10.454 APE10-dist-in 7.532 APE9-dist-in 3.387 K89T TPO160 TPO160 XRAY 2.3 0.231 0.287 A 302 292 3 0 0 0 [[4, 286]] 1.0 2iw6 CMGC_CDK2_HUMAN CMGC 1.8e-89 306.4 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2IW6C P24941 1 295 298.0 QQ2:61296 Type1 Active DFGin 6.378 15.306 BLAminus -148.39, 175.51 55.38, 74.44 -89.04, 21.39 278.81, 70.78 -66.42, -21.32 in-in in 8.477 Saltbr-in 2.876 HRD-in -73.83, -61.91 76.25, 21.43 in-in-in SNCiii in-in ActLoopNT-in 2.839 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.92, 136.02 APE9-dihe-na 64.76, 134.63 APE8-dihe-in -61.82, 140.99 APE8-rot-in 292.75 APE67-dihe-in -30.42, -30.52 -46.23, -72.37 APE12-dist-in 12.643 APE11-dist-in 9.835 APE10-dist-in 7.689 APE9-dist-in 3.426 K89T TPO160 TPO160 XRAY 2.3 0.231 0.287 C 302 295 0 0 0 0 [[4, 286]] 1.0 2iw6 CMGC_CDK2_HUMAN CMGC 1.8e-89 306.4 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: QQ2

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2IW6C
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2IW6A P24941 1 295 298.0 QQ2:61296 Type1 Active DFGin 6.763 15.33 BLAminus -137.04, -179.89 52.44, 77.16 -90.65, 20.03 286.27, 71.9 -65.55, -20.57 in-in in 8.498 Saltbr-in 3.28 HRD-in -76.04, -56.62 74.08, 13.78 in-in-in SNCiii in-in ActLoopNT-in 2.792 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.81, 140.32 APE9-dihe-na 81.92, 120.48 APE8-dihe-in -44.7, 124.8 APE8-rot-in 298.42 APE67-dihe-in -65.53, -21.14 -40.4, -43.63 APE12-dist-in 13.164 APE11-dist-in 10.454 APE10-dist-in 7.532 APE9-dist-in 3.387 K89T TPO160 TPO160 XRAY 2.3 0.231 0.287 A 302 292 3 0 0 0 [[4, 286]] 1.0 2iw6 Homo sapiens CMGC_CDK2_HUMAN CMGC 1.8e-89 306.4 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2IW6C P24941 1 295 298.0 QQ2:61296 Type1 Active DFGin 6.378 15.306 BLAminus -148.39, 175.51 55.38, 74.44 -89.04, 21.39 278.81, 70.78 -66.42, -21.32 in-in in 8.477 Saltbr-in 2.876 HRD-in -73.83, -61.91 76.25, 21.43 in-in-in SNCiii in-in ActLoopNT-in 2.839 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.92, 136.02 APE9-dihe-na 64.76, 134.63 APE8-dihe-in -61.82, 140.99 APE8-rot-in 292.75 APE67-dihe-in -30.42, -30.52 -46.23, -72.37 APE12-dist-in 12.643 APE11-dist-in 9.835 APE10-dist-in 7.689 APE9-dist-in 3.426 K89T TPO160 TPO160 XRAY 2.3 0.231 0.287 C 302 295 0 0 0 0 [[4, 286]] 1.0 2iw6 Homo sapiens CMGC_CDK2_HUMAN CMGC 1.8e-89 306.4 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: QQ2

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name