Ligand: Q6G

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7JU6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR RET RET_HUMAN 7JU6A P07949 713 1012 1114.0 Q6G:61101 Type1 Inactive DFGin 6.6701 14.4363 BLAminus -139.89, -172.14 61.42, 74.93 -98.48, 13.7 281.47, 79.28 -58.44, -32.24 in-in in 7.4861 Saltbr-in 3.2537 HRD-in -72.27, -46.5 78.36, -28.92 in-in-out SNCiio in-out ActLoopNT-in 2.8734 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.29, 18.11 APE9-dihe-in -88.63, 134.88 APE8-dihe-in -53.93, 130.96 APE8-rot-na 329.57 APE67-dihe-in -69.22, -8.74 -44.38, -43.95 APE12-dist-na 13.3173 APE11-dist-na 9.0405 APE10-dist-na 7.4649 APE9-dist-in 5.4815 None None None XRAY 2.06 0.199 0.249 A 314.0 288.0 12 30 30 0 [[724, 1007]] 1.0 7ju6 TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7DU8A P07949 714 1012 1114.0 Q6G:61101 Type1.5_Front Inactive DFGin 6.9592 14.0888 BLAminus -139.9, -176.36 61.28, 71.22 -96.57, 22.61 290.51, 82.58 -62.34, -43.12 in-in in 7.2461 Saltbr-in 2.7254 HRD-in -70.49, -42.48 76.18, -46.1 in-in-out SNCiio in-out ActLoopNT-in 2.9561 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -109.78, 19.85 APE9-dihe-in -91.59, 136.68 APE8-dihe-in -57.27, 135.39 APE8-rot-na 326.69 APE67-dihe-in -68.65, -17.13 -56.96, -36.43 APE12-dist-na 13.4723 APE11-dist-na 9.2178 APE10-dist-na 7.2999 APE9-dist-in 5.6339 None None None XRAY 2.75 0.217 0.277 A 314.0 286.0 13 30 30 0 [[724, 1007]] 1.0 7du8 TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7DU8B P07949 705 1012 1114.0 Q6G:61101 Type1.5_Front Inactive DFGin 6.8661 14.4573 BLAminus -139.37, -177.62 63.4, 72.86 -98.32, 23.3 293.23, 81.57 -64.12, -44.29 in-in in 7.3489 Saltbr-in 3.2265 HRD-in -70.76, -41.16 77.27, -46.88 in-in-out SNCiio in-out ActLoopNT-in 2.9481 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -119.72, 24.05 APE9-dihe-in -92.66, 135.69 APE8-dihe-in -57.1, 135.94 APE8-rot-na 330.01 APE67-dihe-in -67.74, -17.88 -57.22, -36.2 APE12-dist-na 12.9625 APE11-dist-na 8.9549 APE10-dist-na 7.3407 APE9-dist-in 5.6683 None None None XRAY 2.75 0.217 0.277 B 314.0 274.0 31 30 20 10 [[724, 1007]] 1.0 7du8 TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7JU6B P07949 705 1012 1114.0 Q6G:61101 Type1.5_Front Inactive DFGin 6.8529 14.5584 BLAminus -133.87, -179.77 59.88, 75.8 -96.18, 17.81 292.2, 77.2 -56.92, -30.18 in-in in 7.6759 Saltbr-in 2.7169 HRD-in -72.4, -43.27 78.98, -30.91 in-in-out SNCiio in-out ActLoopNT-in 2.9097 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -109.34, 21.56 APE9-dihe-in -92.4, 131.54 APE8-dihe-in -51.97, 128.7 APE8-rot-na 329.4 APE67-dihe-in -67.8, -13.47 -45.61, -41.79 APE12-dist-na 13.2461 APE11-dist-na 9.2191 APE10-dist-na 7.6073 APE9-dist-in 5.405 None None None XRAY 2.06 0.199 0.249 B 314.0 286.0 22 30 21 9 [[724, 1007]] 1.0 7ju6 TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret

Ligand: Q6G

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7JU6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR RET RET_HUMAN 7JU6A P07949 713 1012 1114.0 Q6G:61101 Type1 Inactive DFGin 6.6701 14.4363 BLAminus -139.89, -172.14 61.42, 74.93 -98.48, 13.7 281.47, 79.28 -58.44, -32.24 in-in in 7.4861 Saltbr-in 3.2537 HRD-in -72.27, -46.5 78.36, -28.92 in-in-out SNCiio in-out ActLoopNT-in 2.8734 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.29, 18.11 APE9-dihe-in -88.63, 134.88 APE8-dihe-in -53.93, 130.96 APE8-rot-na 329.57 APE67-dihe-in -69.22, -8.74 -44.38, -43.95 APE12-dist-na 13.3173 APE11-dist-na 9.0405 APE10-dist-na 7.4649 APE9-dist-in 5.4815 None None None XRAY 2.06 0.199 0.249 A 314.0 288.0 12 30 30 0 [[724, 1007]] 1.0 7ju6 Homo sapiens TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7DU8A P07949 714 1012 1114.0 Q6G:61101 Type1.5_Front Inactive DFGin 6.9592 14.0888 BLAminus -139.9, -176.36 61.28, 71.22 -96.57, 22.61 290.51, 82.58 -62.34, -43.12 in-in in 7.2461 Saltbr-in 2.7254 HRD-in -70.49, -42.48 76.18, -46.1 in-in-out SNCiio in-out ActLoopNT-in 2.9561 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -109.78, 19.85 APE9-dihe-in -91.59, 136.68 APE8-dihe-in -57.27, 135.39 APE8-rot-na 326.69 APE67-dihe-in -68.65, -17.13 -56.96, -36.43 APE12-dist-na 13.4723 APE11-dist-na 9.2178 APE10-dist-na 7.2999 APE9-dist-in 5.6339 None None None XRAY 2.75 0.217 0.277 A 314.0 286.0 13 30 30 0 [[724, 1007]] 1.0 7du8 Homo sapiens TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7DU8B P07949 705 1012 1114.0 Q6G:61101 Type1.5_Front Inactive DFGin 6.8661 14.4573 BLAminus -139.37, -177.62 63.4, 72.86 -98.32, 23.3 293.23, 81.57 -64.12, -44.29 in-in in 7.3489 Saltbr-in 3.2265 HRD-in -70.76, -41.16 77.27, -46.88 in-in-out SNCiio in-out ActLoopNT-in 2.9481 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -119.72, 24.05 APE9-dihe-in -92.66, 135.69 APE8-dihe-in -57.1, 135.94 APE8-rot-na 330.01 APE67-dihe-in -67.74, -17.88 -57.22, -36.2 APE12-dist-na 12.9625 APE11-dist-na 8.9549 APE10-dist-na 7.3407 APE9-dist-in 5.6683 None None None XRAY 2.75 0.217 0.277 B 314.0 274.0 31 30 20 10 [[724, 1007]] 1.0 7du8 Homo sapiens TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7JU6B P07949 705 1012 1114.0 Q6G:61101 Type1.5_Front Inactive DFGin 6.8529 14.5584 BLAminus -133.87, -179.77 59.88, 75.8 -96.18, 17.81 292.2, 77.2 -56.92, -30.18 in-in in 7.6759 Saltbr-in 2.7169 HRD-in -72.4, -43.27 78.98, -30.91 in-in-out SNCiio in-out ActLoopNT-in 2.9097 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -109.34, 21.56 APE9-dihe-in -92.4, 131.54 APE8-dihe-in -51.97, 128.7 APE8-rot-na 329.4 APE67-dihe-in -67.8, -13.47 -45.61, -41.79 APE12-dist-na 13.2461 APE11-dist-na 9.2191 APE10-dist-na 7.6073 APE9-dist-in 5.405 None None None XRAY 2.06 0.199 0.249 B 314.0 286.0 22 30 21 9 [[724, 1007]] 1.0 7ju6 Homo sapiens TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret

Ligand: Q6G

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name