Ligand: P49

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2WIPA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2WIPA P24941 1 298 298.0 P49:61299 Type1 Inactive DFGin 6.213 14.953 BLAminus -142.46, 178.98 56.18, 81.9 -99.03, 23.63 283.85, 66.21 -56.05, -33.18 in-in in 8.634 Saltbr-in 2.853 HRD-in -72.23, -57.81 81.71, -8.44 in-in-out SNCiio in-out ActLoopNT-in 2.799 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -130.17, 149.32 APE9-dihe-na -61.56, 147.19 APE8-dihe-in -53.43, 148.35 APE8-rot-out 180.82 APE67-dihe-in -63.04, -20.64 -55.16, -41.78 APE12-dist-in 10.952 APE11-dist-out 6.172 APE10-dist-out 9.445 APE9-dist-in 3.754 None None None XRAY 2.8 0.221 0.258 A 309 293 5 0 0 0 [[4, 286]] 1.0 2wip CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2WIPC P24941 1 296 298.0 P49:61297 Type1 Inactive DFGin 6.239 14.98 BLAminus -141.29, -179.48 53.82, 83.38 -100.32, 23.88 283.87, 67.06 -55.38, -33.16 in-in in 8.625 Saltbr-in 2.839 HRD-in -72.71, -56.85 82.33, -8.67 in-in-out SNCiio in-out ActLoopNT-in 2.807 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -114.79, -53.2 APE9-dihe-na -69.06, 145.9 APE8-dihe-in -52.62, 147.98 APE8-rot-out 180.17 APE67-dihe-in -61.14, -22.34 -56.62, -40.71 APE12-dist-in 13.16 APE11-dist-in 12.121 APE10-dist-in 6.699 APE9-dist-in 3.739 None None None XRAY 2.8 0.221 0.258 C 309 291 5 0 0 0 [[4, 286]] 1.0 2wip CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: P49

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2WIPA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2WIPA P24941 1 298 298.0 P49:61299 Type1 Inactive DFGin 6.213 14.953 BLAminus -142.46, 178.98 56.18, 81.9 -99.03, 23.63 283.85, 66.21 -56.05, -33.18 in-in in 8.634 Saltbr-in 2.853 HRD-in -72.23, -57.81 81.71, -8.44 in-in-out SNCiio in-out ActLoopNT-in 2.799 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -130.17, 149.32 APE9-dihe-na -61.56, 147.19 APE8-dihe-in -53.43, 148.35 APE8-rot-out 180.82 APE67-dihe-in -63.04, -20.64 -55.16, -41.78 APE12-dist-in 10.952 APE11-dist-out 6.172 APE10-dist-out 9.445 APE9-dist-in 3.754 None None None XRAY 2.8 0.221 0.258 A 309 293 5 0 0 0 [[4, 286]] 1.0 2wip Homo sapiens CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2WIPC P24941 1 296 298.0 P49:61297 Type1 Inactive DFGin 6.239 14.98 BLAminus -141.29, -179.48 53.82, 83.38 -100.32, 23.88 283.87, 67.06 -55.38, -33.16 in-in in 8.625 Saltbr-in 2.839 HRD-in -72.71, -56.85 82.33, -8.67 in-in-out SNCiio in-out ActLoopNT-in 2.807 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -114.79, -53.2 APE9-dihe-na -69.06, 145.9 APE8-dihe-in -52.62, 147.98 APE8-rot-out 180.17 APE67-dihe-in -61.14, -22.34 -56.62, -40.71 APE12-dist-in 13.16 APE11-dist-in 12.121 APE10-dist-in 6.699 APE9-dist-in 3.739 None None None XRAY 2.8 0.221 0.258 C 309 291 5 0 0 0 [[4, 286]] 1.0 2wip Homo sapiens CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: P49

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name