Ligand: NF5

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4D2WD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK MELK MELK_HUMAN 4D2WA Q14680 1 333 651.0 NF5:1334 Type1 Inactive DFGin 6.8296 15.8487 BLAminus -125.83, 179.01 60.38, 71.2 -91.14, 19.27 280.32, 83.34 -59.66, -12.38 in-in in 9.216 Saltbr-in 2.7476 HRD-in -75.99, -44.93 74.79, -3.19 in-in-out SNCiio in-out ActLoopNT-in 3.4636 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoi APE10-dihe-na 999.0, -2.63 APE9-dihe-na -81.94, -156.44 APE8-dihe-in -43.49, 125.45 APE8-rot-none 999.0 APE67-dihe-in -58.36, -22.97 -57.41, -41.21 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 8.2268 APE9-dist-in 4.1644 T167A,S171A,N213T,V214A,M215A,Y218V,K219A None None XRAY 1.92 0.203 0.247 A 356.0 314.0 19 29 16 13 [[11, 263]] 1.0 4d2w CAMK_MELK_HUMAN CAMK 4.6e-87 297.7 1.0 256.0 256.0 149 150 151 153 155 40 57 61 129 131 130 132.0 191 178 173 172 171 170 169 168 167 87 Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2WB Q14680 1 333 651.0 NF5:1334 Type1 Inactive DFGin 6.7685 16.0738 BLAminus -125.1, -179.85 60.72, 70.54 -91.12, 19.55 280.74, 84.12 -68.55, -21.97 in-in in 9.7978 Saltbr-in 2.89 HRD-in -70.01, -49.15 73.95, -4.32 in-in-out SNCiio in-out ActLoopNT-in 2.8093 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoi APE10-dihe-na 999.0, -40.67 APE9-dihe-na 98.2, 159.82 APE8-dihe-in -49.9, 128.2 APE8-rot-none 999.0 APE67-dihe-in -59.11, -23.33 -59.28, -43.21 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 8.7768 APE9-dist-in 4.7388 T167A,S171A,N213T,V214A,M215A,Y218V,K219A None None XRAY 1.92 0.203 0.247 B 356.0 323.0 10 29 23 6 [[11, 263]] 1.0 4d2w CAMK_MELK_HUMAN CAMK 4.6e-87 297.7 1.0 256.0 256.0 149 150 151 153 155 40 57 61 129 131 130 132.0 191 178 173 172 171 170 169 168 167 87 Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2WC Q14680 1 333 651.0 NF5:1334 Type1 None DFGin 6.8567 15.6417 BLAminus -123.79, 178.59 60.65, 71.55 -90.39, 19.57 282.34, 80.84 -69.3, -20.74 in-in in 8.998 Saltbr-in 2.7431 HRD-in -74.38, -48.87 73.02, -0.95 in-in-none SNCiin in-none ActLoopNT-in 3.019 ActLoopCT-none nonTYR APEdihe_aaini APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 151.96 APE8-dihe-in -49.29, 128.09 APE8-rot-none 999.0 APE67-dihe-in -59.65, -22.66 -56.52, -44.97 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.7473 T167A,S171A,N213T,V214A,M215A,Y218V,K219A None None XRAY 1.92 0.203 0.247 C 356.0 313.0 20 29 16 13 [[11, 263]] 1.0 4d2w CAMK_MELK_HUMAN CAMK 4.6e-87 297.7 1.0 256.0 256.0 149 150 151 153 155 40 57 61 129 131 130 132.0 191 178 173 172 171 170 169 168 167 87 Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2WD Q14680 1 333 651.0 NF5:1334 Type1 Inactive DFGin 6.7568 16.1285 BLAminus -128.17, -179.29 58.65, 70.87 -91.82, 22.28 279.98, 81.85 -70.97, -17.86 in-out in 9.9127 Saltbr-out 4.0327 HRD-in -75.62, -48.39 73.85, -2.17 out-in-none SNCoin in-none ActLoopNT-in 2.7897 ActLoopCT-none nonTYR APEdihe_aaini APEdist_nnii APE10-dihe-na 999.0, 100.44 APE9-dihe-na 72.37, -170.19 APE8-dihe-in -42.49, 122.48 APE8-rot-none 999.0 APE67-dihe-in -59.49, -22.83 -54.25, -42.44 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 5.9529 APE9-dist-in 4.8323 T167A,S171A,N213T,V214A,M215A,Y218V,K219A None None XRAY 1.92 0.203 0.247 D 356.0 326.0 7 29 22 7 [[11, 263]] 1.0 4d2w CAMK_MELK_HUMAN CAMK 4.6e-87 297.7 1.0 256.0 256.0 149 150 151 153 155 40 57 61 129 131 130 132.0 191 178 173 172 171 170 169 168 167 87 Maternal embryonic leucine zipper kinase

Ligand: NF5

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4D2WD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK MELK MELK_HUMAN 4D2WA Q14680 1 333 651.0 NF5:1334 Type1 Inactive DFGin 6.8296 15.8487 BLAminus -125.83, 179.01 60.38, 71.2 -91.14, 19.27 280.32, 83.34 -59.66, -12.38 in-in in 9.216 Saltbr-in 2.7476 HRD-in -75.99, -44.93 74.79, -3.19 in-in-out SNCiio in-out ActLoopNT-in 3.4636 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoi APE10-dihe-na 999.0, -2.63 APE9-dihe-na -81.94, -156.44 APE8-dihe-in -43.49, 125.45 APE8-rot-none 999.0 APE67-dihe-in -58.36, -22.97 -57.41, -41.21 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 8.2268 APE9-dist-in 4.1644 T167A,S171A,N213T,V214A,M215A,Y218V,K219A None None XRAY 1.92 0.203 0.247 A 356.0 314.0 19 29 16 13 [[11, 263]] 1.0 4d2w Homo sapiens CAMK_MELK_HUMAN CAMK 4.6e-87 297.7 1.0 256.0 256.0 149 150 151 153 155 40 57 61 129 131 130 132.0 191 178 173 172 171 170 169 168 167 87 Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2WB Q14680 1 333 651.0 NF5:1334 Type1 Inactive DFGin 6.7685 16.0738 BLAminus -125.1, -179.85 60.72, 70.54 -91.12, 19.55 280.74, 84.12 -68.55, -21.97 in-in in 9.7978 Saltbr-in 2.89 HRD-in -70.01, -49.15 73.95, -4.32 in-in-out SNCiio in-out ActLoopNT-in 2.8093 ActLoopCT-out nonTYR APEdihe_aaini APEdist_nnoi APE10-dihe-na 999.0, -40.67 APE9-dihe-na 98.2, 159.82 APE8-dihe-in -49.9, 128.2 APE8-rot-none 999.0 APE67-dihe-in -59.11, -23.33 -59.28, -43.21 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 8.7768 APE9-dist-in 4.7388 T167A,S171A,N213T,V214A,M215A,Y218V,K219A None None XRAY 1.92 0.203 0.247 B 356.0 323.0 10 29 23 6 [[11, 263]] 1.0 4d2w Homo sapiens CAMK_MELK_HUMAN CAMK 4.6e-87 297.7 1.0 256.0 256.0 149 150 151 153 155 40 57 61 129 131 130 132.0 191 178 173 172 171 170 169 168 167 87 Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2WC Q14680 1 333 651.0 NF5:1334 Type1 None DFGin 6.8567 15.6417 BLAminus -123.79, 178.59 60.65, 71.55 -90.39, 19.57 282.34, 80.84 -69.3, -20.74 in-in in 8.998 Saltbr-in 2.7431 HRD-in -74.38, -48.87 73.02, -0.95 in-in-none SNCiin in-none ActLoopNT-in 3.019 ActLoopCT-none nonTYR APEdihe_aaini APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 151.96 APE8-dihe-in -49.29, 128.09 APE8-rot-none 999.0 APE67-dihe-in -59.65, -22.66 -56.52, -44.97 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.7473 T167A,S171A,N213T,V214A,M215A,Y218V,K219A None None XRAY 1.92 0.203 0.247 C 356.0 313.0 20 29 16 13 [[11, 263]] 1.0 4d2w Homo sapiens CAMK_MELK_HUMAN CAMK 4.6e-87 297.7 1.0 256.0 256.0 149 150 151 153 155 40 57 61 129 131 130 132.0 191 178 173 172 171 170 169 168 167 87 Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 4D2WD Q14680 1 333 651.0 NF5:1334 Type1 Inactive DFGin 6.7568 16.1285 BLAminus -128.17, -179.29 58.65, 70.87 -91.82, 22.28 279.98, 81.85 -70.97, -17.86 in-out in 9.9127 Saltbr-out 4.0327 HRD-in -75.62, -48.39 73.85, -2.17 out-in-none SNCoin in-none ActLoopNT-in 2.7897 ActLoopCT-none nonTYR APEdihe_aaini APEdist_nnii APE10-dihe-na 999.0, 100.44 APE9-dihe-na 72.37, -170.19 APE8-dihe-in -42.49, 122.48 APE8-rot-none 999.0 APE67-dihe-in -59.49, -22.83 -54.25, -42.44 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 5.9529 APE9-dist-in 4.8323 T167A,S171A,N213T,V214A,M215A,Y218V,K219A None None XRAY 1.92 0.203 0.247 D 356.0 326.0 7 29 22 7 [[11, 263]] 1.0 4d2w Homo sapiens CAMK_MELK_HUMAN CAMK 4.6e-87 297.7 1.0 256.0 256.0 149 150 151 153 155 40 57 61 129 131 130 132.0 191 178 173 172 171 170 169 168 167 87 Maternal embryonic leucine zipper kinase

Ligand: NF5

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name