Ligand: MTZ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2UUEA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2UUEA P24941 1 296 298.0 MTZ:1297 Type1 Inactive DFGin 6.668 15.552 BLAminus -136.51, -179.65 55.04, 76.1 -99.46, 27.06 276.81, 66.03 -71.99, -20.9 in-in in 8.424 Saltbr-in 2.99 HRD-in -83.38, -47.65 80.14, -16.01 in-in-out SNCiio in-out ActLoopNT-in 2.883 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oioi APE10-dihe-na -101.45, 44.37 APE9-dihe-na -136.17, 15.14 APE8-dihe-out 83.13, 148.34 APE8-rot-out 226.35 APE67-dihe-in -65.4, -22.8 -105.43, -48.8 APE12-dist-out 14.683 APE11-dist-in 11.62 APE10-dist-out 9.277 APE9-dist-in 5.446 None None None XRAY 2.06 0.197 0.244 A 298 296 0 0 0 0 [[4, 286]] 1.0 2uue CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2UUEC P24941 1 297 298.0 MTZ:1298 Type1 Inactive DFGin 6.549 15.634 BLAminus -139.6, 174.69 63.14, 72.39 -91.13, 24.55 277.59, 65.12 -71.23, -27.72 in-in in 8.585 Saltbr-in 2.887 HRD-in -84.99, -51.24 81.34, -14.94 in-in-out SNCiio in-out ActLoopNT-in 2.846 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oioi APE10-dihe-na -103.79, 100.15 APE9-dihe-na -148.09, 37.68 APE8-dihe-out 71.12, 132.14 APE8-rot-in 268.33 APE67-dihe-in -63.15, -29.14 -103.73, -38.08 APE12-dist-out 14.954 APE11-dist-in 10.215 APE10-dist-out 10.31 APE9-dist-in 5.642 None None None XRAY 2.06 0.197 0.244 C 298 297 0 0 0 0 [[4, 286]] 1.0 2uue CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: MTZ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2UUEA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2UUEA P24941 1 296 298.0 MTZ:1297 Type1 Inactive DFGin 6.668 15.552 BLAminus -136.51, -179.65 55.04, 76.1 -99.46, 27.06 276.81, 66.03 -71.99, -20.9 in-in in 8.424 Saltbr-in 2.99 HRD-in -83.38, -47.65 80.14, -16.01 in-in-out SNCiio in-out ActLoopNT-in 2.883 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oioi APE10-dihe-na -101.45, 44.37 APE9-dihe-na -136.17, 15.14 APE8-dihe-out 83.13, 148.34 APE8-rot-out 226.35 APE67-dihe-in -65.4, -22.8 -105.43, -48.8 APE12-dist-out 14.683 APE11-dist-in 11.62 APE10-dist-out 9.277 APE9-dist-in 5.446 None None None XRAY 2.06 0.197 0.244 A 298 296 0 0 0 0 [[4, 286]] 1.0 2uue Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2UUEC P24941 1 297 298.0 MTZ:1298 Type1 Inactive DFGin 6.549 15.634 BLAminus -139.6, 174.69 63.14, 72.39 -91.13, 24.55 277.59, 65.12 -71.23, -27.72 in-in in 8.585 Saltbr-in 2.887 HRD-in -84.99, -51.24 81.34, -14.94 in-in-out SNCiio in-out ActLoopNT-in 2.846 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oioi APE10-dihe-na -103.79, 100.15 APE9-dihe-na -148.09, 37.68 APE8-dihe-out 71.12, 132.14 APE8-rot-in 268.33 APE67-dihe-in -63.15, -29.14 -103.73, -38.08 APE12-dist-out 14.954 APE11-dist-in 10.215 APE10-dist-out 10.31 APE9-dist-in 5.642 None None None XRAY 2.06 0.197 0.244 C 298 297 0 0 0 0 [[4, 286]] 1.0 2uue Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: MTZ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name