Ligand: MTW

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 2C5XA
DFGin BLBminus 1 33.3% 2C5YA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2C5XA P24941 1 296 298.0 MTW:1297 Type1 Inactive DFGin 6.456 15.49 BLAminus -147.14, 173.63 64.88, 81.13 -99.82, 31.9 280.01, 44.97 -72.1, -29.12 in-in in 8.351 Saltbr-in 3.421 HRD-in -95.4, -39.54 63.25, -15.18 in-in-out SNCiio in-out ActLoopNT-in 2.869 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oioi APE10-dihe-na -84.91, 67.81 APE9-dihe-na -125.9, -36.28 APE8-dihe-out 122.49, 156.35 APE8-rot-out 176.62 APE67-dihe-out 57.5, -47.85 -96.74, -115.33 APE12-dist-out 14.12 APE11-dist-in 11.374 APE10-dist-out 9.051 APE9-dist-in 5.854 None None None XRAY 2.9 0.203 0.264 A 298 296 0 0 0 0 [[4, 286]] 1.0 2c5x CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2C5XC P24941 1 296 298.0 MTW:1297 Type1 Inactive DFGin 6.478 15.536 BLAminus -137.8, 171.4 74.5, 81.98 -98.98, 18.7 276.64, 65.26 -59.32, -18.19 in-in in 8.872 Saltbr-in 3.325 HRD-in -99.79, -42.03 69.9, -20.79 in-in-out SNCiio in-out ActLoopNT-in 2.841 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -106.41, 92.79 APE9-dihe-na -94.18, -148.42 APE8-dihe-in -127.45, 167.08 APE8-rot-out 106.98 APE67-dihe-in -21.73, -45.61 -109.0, -46.95 APE12-dist-out 14.979 APE11-dist-in 9.273 APE10-dist-out 11.28 APE9-dist-out 6.942 None None None XRAY 2.9 0.203 0.264 C 298 296 0 0 0 0 [[4, 286]] 1.0 2c5x CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2C5YA P24941 1 297 298.0 MTW:1298 Type1 Inactive DFGin 9.4 16.657 BLBminus -119.33, 163.14 63.9, 25.09 -37.93, 176.97 281.77, 102.48 32.41, -5.42 out-out out 15.829 Saltbr-out 18.808 HRD-in -83.1, -53.31 80.34, -18.94 out-out-out SNCooo out-out ActLoopNT-out 5.984 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -76.09, 126.86 APE9-dihe-na -82.0, 122.2 APE8-dihe-in -67.98, 138.89 APE8-rot-out 178.11 APE67-dihe-in -60.87, -23.53 -96.51, 2.32 APE12-dist-out 19.365 APE11-dist-out 17.172 APE10-dist-out 18.356 APE9-dist-out 10.546 None None None XRAY 2.25 0.172 0.295 A 298 290 7 0 0 0 [[4, 286]] 1.0 2c5y CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: MTW

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 2C5XA
DFGin BLBminus 1 33.3% 2C5YA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2C5XA P24941 1 296 298.0 MTW:1297 Type1 Inactive DFGin 6.456 15.49 BLAminus -147.14, 173.63 64.88, 81.13 -99.82, 31.9 280.01, 44.97 -72.1, -29.12 in-in in 8.351 Saltbr-in 3.421 HRD-in -95.4, -39.54 63.25, -15.18 in-in-out SNCiio in-out ActLoopNT-in 2.869 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oioi APE10-dihe-na -84.91, 67.81 APE9-dihe-na -125.9, -36.28 APE8-dihe-out 122.49, 156.35 APE8-rot-out 176.62 APE67-dihe-out 57.5, -47.85 -96.74, -115.33 APE12-dist-out 14.12 APE11-dist-in 11.374 APE10-dist-out 9.051 APE9-dist-in 5.854 None None None XRAY 2.9 0.203 0.264 A 298 296 0 0 0 0 [[4, 286]] 1.0 2c5x Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2C5XC P24941 1 296 298.0 MTW:1297 Type1 Inactive DFGin 6.478 15.536 BLAminus -137.8, 171.4 74.5, 81.98 -98.98, 18.7 276.64, 65.26 -59.32, -18.19 in-in in 8.872 Saltbr-in 3.325 HRD-in -99.79, -42.03 69.9, -20.79 in-in-out SNCiio in-out ActLoopNT-in 2.841 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -106.41, 92.79 APE9-dihe-na -94.18, -148.42 APE8-dihe-in -127.45, 167.08 APE8-rot-out 106.98 APE67-dihe-in -21.73, -45.61 -109.0, -46.95 APE12-dist-out 14.979 APE11-dist-in 9.273 APE10-dist-out 11.28 APE9-dist-out 6.942 None None None XRAY 2.9 0.203 0.264 C 298 296 0 0 0 0 [[4, 286]] 1.0 2c5x Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2C5YA P24941 1 297 298.0 MTW:1298 Type1 Inactive DFGin 9.4 16.657 BLBminus -119.33, 163.14 63.9, 25.09 -37.93, 176.97 281.77, 102.48 32.41, -5.42 out-out out 15.829 Saltbr-out 18.808 HRD-in -83.1, -53.31 80.34, -18.94 out-out-out SNCooo out-out ActLoopNT-out 5.984 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -76.09, 126.86 APE9-dihe-na -82.0, 122.2 APE8-dihe-in -67.98, 138.89 APE8-rot-out 178.11 APE67-dihe-in -60.87, -23.53 -96.51, 2.32 APE12-dist-out 19.365 APE11-dist-out 17.172 APE10-dist-out 18.356 APE9-dist-out 10.546 None None None XRAY 2.25 0.172 0.295 A 298 290 7 0 0 0 [[4, 286]] 1.0 2c5y Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: MTW

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name